January
- Marco Colonna, MD
$172,500 from Cure Alzheimer’s Fund for “Understanding the Role of Natural Ab-Specific B Cell Responses in AD Progression”
$107,258 from Aclaris Therapeutics for “Study of Gut-Selective vs. Systemic Jak Inhibitors in Pre-Clinical Models of IBD” - Kodi Ravichandran, PhD
$583,731 from NIH for “Solute carrier proteins in efferocytosis and inflammation”
$334,393 from NIH for “Mechanisms regulating apoptotic cell clearance in health and disease” - Steven L. Teitelbaum, MD
$457,219 from NIH for “Hepatic steatosis promotes liver metastasis” - Parker Wilson, MD, PhD
$167,826 from NIH for “The Single Cell Landscape of Early Human Diabetic Nephropathy”
February
- Marco Colonna, MD
$624,511 from NIH for “Ontogenetic niche of B cells at the CNS borders in homeostasis, aging and autoimmunity” - Ali Ellebedy, PhD
$354,375 from NIH for “Structural interrogation of vaccine- and infection-induced B cell responses” - Gwendalyn Randolph, PhD
$544,177 from NIH for “Mechanisms that alter lymphatic transport in inflammatory bowel disease” - Emil Unanue, MD
$471,535 from NIH for “ADMR – Autoimmune Diabetes: Macrophage Responses”
March
- Maxim Artyomov, PhD
$128,178 from Genentech for “Stochastic simulations of TCR-MHC interactions”
$321,271 from Aging Biology Foundation for “Aging Human Tissues Systems Level Dissection of Immune Aging”
$446,357 from Aging Biology Foundation for “Personnel Systems Level Dissection of Human Aging” - Ali Ellebedy, PhD
$148,226 from NIH for “Understanding the Impact of Imprinting and Repeat Antigen Exposure on Durability of Antibody Responses to the Influenza Virus” - Ta-Chiang Liu, MD, PhD
$34,085 from NIH for “Paneth Cell Heterogeneity in Infection and Inflammation”
$160,001 from Interline Therapeutics for “Developing a translational understanding of high impact genetic variants in inflammatory bowel disease” - Bernd H. Zinselmeyer, PhD
$30,000 from Genentech for “Characterizing the impact of CD2AP and CIN85 on Leucocyte motility in real time in vivo”
April
- Gautam Dantas, PhD
$60,000 from The Foundation For Barnes-Jewish Hospital for “CTRFP Strain tracking and genomic characterization of Pseudomonas aeruginosa across clinical and environmental samples in the BJH healthcare system” - Brian Edelson, MD, PhD
$236,250 from NIH for “Selective induction of alloantigen-specific humoral tolerance by MHC-Fc fusion proteins” - Jonathan Kipnis, PhD
$345,000 from Cure Alzheimer’s Fund for “Berg Brain Entry & Exit Consortium: Crosstalk of CNS barriers and clearance routes in homeostasis and Alzheimer’s disease” - Melanie L. Yarbrough, PhD
$110,076 from bioMerieux for “bioMerieux IIR Program”
May
- Gaya K. Amarasinghe, PhD
$59,999 from Alzheimer’s Association for “DEVi Engineered decoy viral inhibitors (DEVi) to prevent Tau spread by Lrp1” - Marco Colonna, MD
$430,655 from NIH for “Soluble TREM2 regulation of microglial function in Alzheimer disease”
$196,875 from NIH for “Impact of polyamines on ILC3 function at steady state and in preclinical model of colitis” - Brian Edelson, MD, PhD
$176,889 from National Multiple Sclerosis Society for “T cell-intrinsic roles for the ZFP36 family proteins in MS and EAE”
June
- Marco Colonna, MD
$149,999 from Kenneth Rainin Foundation for “How intraepithelial TCRgd T cell subsets maintain intestinal homeostasis” - Brian Edelson, MD, PhD
$319,584 from NIH for “Role of Intestinal Parasites on Regulating Immune Responses to Gut Antigens” - Ta-Chiang Liu, MD, PhD
$149,999 from Kenneth Rainin Foundation for “Autophagy shapes Debaryomyces hansenii invasion in Crohn’s disease” - Kenneth Murphy, MD, PhD
$559,854 from NIH for “Molecular Basis of cDC1 Development” - Steve Persaud, MD, PhD
One-year, $70,000 Developmental Research Program award from the Washington University Specialized Program of Research Excellence (SPORE) in Leukemia for his project entitled: “Maximizing antileukemia effect and minimizing toxicity of antibody-based HSCT conditioning”
July
- Robert Schreiber, PhD
$401,129 from NIH for “Training in the Immunobiology and Molecular Cell Biology of Cancer” - Steven L. Teitelbaum, MD
$1,000 from The Foundation For Barnes-Jewish Hospital for “Avioli Lecture Award”
$39,413 for The Foundation For Barnes-Jewish Hospital for “Sonnenwirth Lecture Award”
August
- Gaya K. Amarasinghe, PhD
$393,750 from NIH for “Development and Characterization of Engineering Therapeutic Antibodies Against SARS-CoV-2” - Jonathan Kipnis, PhD
$585,577 from NIH for “Aged T-cell-derived cytokines impact meningeal lymphatics and contribute to AD”
$827,228 from NIH for “Neuroimmunology of AD and CAA with focus on innate immunity and lymphatics” - Katherine Schwetye, MD, PhD
$410,984 from NIH for “Human in vivo stable isotope labeling kinetics (iSILK) to quantify brain amyloid plaque kinetics”
September
- Eric Duncavage, MD
$261,450 from NIH for “Whole Genome Sequencing for Genomic Evaluation and Risk Stratification of Patients with Myelodysplastic Syndromes” - Steve Persaud, MD, PhD
One-year, $204,944 research supplement to Dr. John DiPersio’s R35 grant for the project entitled “Optimizing Hematopoietic Stem Cell Transplantation for the Treatment of Hematological Malignancies”
July
- Ali Ellebedy, PhD
$110,000 from Bill & Melinda Gates Foundation for “Early Events and Role of FcR Pathways in Immunity to mRNA Vaccines” - Steven L. Teitelbaum, MD
$10,000 from The Foundation For Barnes-Jewish Hospital for “Avioli Lecture Award”
August
- Gautam Dantas, PhD
$748,687 from CDC for “Interrogating the Phylogenomics and Mobilome of Colonizing Multidrug Resistant Organisms (MDROs) in Hospitalized Patients and Community-Dwellers in Pakistan”
September
- Daved Fremont, PhD
$1.39M from NIH for “B Cell Epitope Discovery and Mechanisms of Antibody Protection” - Jonathan Kipnis, PhD
$249,999 from Carol and Gene Ludwig Family Foundation for “Exhibit B-3 Meningeal lymphatic vessels in Alzheimer’s disease” - Nima Mosammaparast, MD, PhD
$45,000 from NIH for “Structural Cell Biology of DNA Repair Machines”
October
- Kathleen Sheehan, PhD
$300,000 from NGM Biopharmaceuticals for “Elucidating the Role of LAIR1 in Controlling Tumor Immunity”
November
- Gautam Dantas, PhD
$123,589 from bioMerieux for “Validation of bioMerieux EPISEQ CS and EPISEQ 16S using Wash U whole bacterial genomes and metagenomics 16S rRNA gene sequence databases” - Takeshi Egawa, MD, PhD
$78,750 from NIH for “Developing tools to study relationship between oxidative stress in T cell dysfunction” - Jeffrey Gordon, MD
$824,113 from Bill & Melinda Gates Foundation for “Maternal Microbiome directed therapeutic foods development”
December
- Ali Ellebedy, PhD
$735,765 from Moderna Therapeutics for “Defining the Cross-Reactivity and Durability of Human B Cell Responses to SARS-CoV-2 Variants-Based mRNA Vaccination”
$1.13M from Moderna Therapeutics for “Defining the Diversity and Specificity of Human B Cell Response to Influenza Virus mRNA-Based Vaccines” - Scott Handley, PhD
$52,838 from The Leona M. and Harry B. Helmsley Charitable Trust for “Anti-phage Antibodies in Stratifying Crohn’s Disease Diagnosis and Treatment Response” - Jonathan Kipnis, PhD
$172,500 from Cure Alzheimer’s Fund for “Contribution of skull bone marrow-derived cells to Alzheimer’s disease”
$300,000 from anonymous foundation for “Contribution of skull bone marrow-derived cells to Alzheimer’s disease”