Grants & Notables

March

• Cathy Ma, MD, PhD
  $50,000, one-year Clinical and Translational Research Funding Program (CTRFP) award for “Define the Utility of Autophagy-Associated ATG16L1 T300A Genotype in Prognostic Stratification of Hepatocellular Carcinoma”

January

• Marco Colonna, MD
  $172,500 from Cure Alzheimer’s Fund for “Understanding the Role of Natural Ab-Specific B Cell Responses in AD Progression”
  $107,258 from Aclaris Therapeutics for “Study of Gut-Selective vs. Systemic Jak Inhibitors in Pre-Clinical Models of IBD”
• Kodi Ravichandran, PhD
  $583,731 from NIH for “Solute carrier proteins in efferocytosis and inflammation”
  $334,393 from NIH for “Mechanisms regulating apoptotic cell clearance in health and disease”
• Steven L. Teitelbaum, MD
  $457,219 from NIH for “Hepatic steatosis promotes liver metastasis”
• Parker Wilson, MD, PhD
  $167,826 from NIH for “The Single Cell Landscape of Early Human Diabetic Nephropathy”

February

• Marco Colonna, MD
  $624,511 from NIH for “Ontogenetic niche of B cells at the CNS borders in homeostasis, aging and autoimmunity”
• Ali Ellebedy, PhD
  $354,375 from NIH for “Structural interrogation of vaccine- and infection-induced B cell responses”
• Gwendalyn Randolph, PhD
  $544,177 from NIH for “Mechanisms that alter lymphatic transport in inflammatory bowel disease”
• Emil Unanue, MD
  $471,535 from NIH for “ADMR – Autoimmune Diabetes: Macrophage Responses”

March

• Maxim Artyomov, PhD
  $128,178 from Genentech for “Stochastic simulations of TCR-MHC interactions”
  $321,271 from Aging Biology Foundation for “Aging Human Tissues Systems Level Dissection of Immune Aging”
  $446,357 from Aging Biology Foundation for “Personnel Systems Level Dissection of Human Aging”
• Ali Ellebedy, PhD
  $148,226 from NIH for “Understanding the Impact of Imprinting and Repeat Antigen Exposure on Durability of Antibody Responses to the Influenza Virus”
• Ta-Chiang Liu, MD, PhD
  $34,085 from NIH for “Paneth Cell Heterogeneity in Infection and Inflammation”
  $160,001 from Interline Therapeutics for “Developing a translational understanding of high impact genetic variants in inflammatory bowel disease”
• Bernd H. Zinselmeyer, PhD
  $30,000 from Genentech for “Characterizing the impact of CD2AP and CIN85 on Leucocyte motility in real time in vivo”

April

• Gautam Dantas, PhD
  $60,000 from The Foundation For Barnes-Jewish Hospital for “CTRFP Strain tracking and genomic characterization of Pseudomonas aeruginosa across clinical and environmental samples in the BJH healthcare system”
• Brian Edelson, MD, PhD
  $236,250 from NIH for “Selective induction of alloantigen-specific humoral tolerance by MHC-Fc fusion proteins”
• Jonathan Kipnis, PhD
  $345,000 from Cure Alzheimer’s Fund for “Berg Brain Entry & Exit Consortium: Crosstalk of CNS barriers and clearance routes in homeostasis and Alzheimer’s disease”
• Melanie L. Yarbrough, PhD
  $110,076 from bioMerieux for “bioMerieux IIR Program”

May

• Marco Colonna, MD
  $430,655 from NIH for “Soluble TREM2 regulation of microglial function in Alzheimer disease”
  $196,875 from NIH for “Impact of polyamines on ILC3 function at steady state and in preclinical model of colitis”
• Brian Edelson, MD, PhD
  $176,889 from National Multiple Sclerosis Society for “T cell-intrinsic roles for the ZFP36 family proteins in MS and EAE”

June

• Marco Colonna, MD
  $149,999 from Kenneth Rainin Foundation for “How intraepithelial TCRgd T cell subsets maintain intestinal homeostasis”
• Brian Edelson, MD, PhD
  $319,584 from NIH for “Role of Intestinal Parasites on Regulating Immune Responses to Gut Antigens”
• Ta-Chiang Liu, MD, PhD
  $149,999 from Kenneth Rainin Foundation for “Autophagy shapes Debaryomyces hansenii invasion in Crohn’s disease”
• Kenneth Murphy, MD, PhD
  $559,854 from NIH for “Molecular Basis of cDC1 Development”
• Steve Persaud, MD, PhD
  One-year, $70,000 Developmental Research Program award from the Washington University Specialized Program of Research Excellence (SPORE) in Leukemia for his project entitled: “Maximizing antileukemia effect and minimizing toxicity of antibody-based HSCT conditioning”

July

• Robert Schreiber, PhD
  $401,129 from NIH for “Training in the Immunobiology and Molecular Cell Biology of Cancer”
• Steven L. Teitelbaum, MD
  $1,000 from The Foundation For Barnes-Jewish Hospital for “Avioli Lecture Award”
  $39,413 for The Foundation For Barnes-Jewish Hospital for “Sonnenwirth Lecture Award”

August

• Jonathan Kipnis, PhD
  $585,577 from NIH for “Aged T-cell-derived cytokines impact meningeal lymphatics and contribute to AD”
  $827,228 from NIH for “Neuroimmunology of AD and CAA with focus on innate immunity and lymphatics”
• Abraham Qavi, MD, PhD
  $761,686, 4-year, Mentored Clinical Scientist Research Career Development Award (K08 award) from NIH for “Development of Optofluidic Resonators for Filoviral Detection”
• Katherine Schwetye, MD, PhD
  $410,984 from NIH for “Human in vivo stable isotope labeling kinetics (iSILK) to quantify brain amyloid plaque kinetics”

September

• Eric Duncavage, MD
  $261,450 from NIH for “Whole Genome Sequencing for Genomic Evaluation and Risk Stratification of Patients with Myelodysplastic Syndromes”
• Steve Persaud, MD, PhD
  One-year, $204,944 research supplement to Dr. John DiPersio’s R35 grant for the project entitled “Optimizing Hematopoietic Stem Cell Transplantation for the Treatment of Hematological Malignancies”

December

• Marco Colonna, MD
  $499,998 from NIH for “Impact of Meningeal B Cells in Central Nervous System Autoimmunity”
• Takeshi Egawa, MD, PhD
  $300,000 from NIH for “CD8 T cell fate decision instructed by IL-2”

July

• Ali Ellebedy, PhD
  $110,000 from Bill & Melinda Gates Foundation for “Early Events and Role of FcR Pathways in Immunity to mRNA Vaccines”
• Steven L. Teitelbaum, MD
  $10,000 from The Foundation For Barnes-Jewish Hospital for “Avioli Lecture Award”

August

• Gautam Dantas, PhD
  $748,687 from CDC for “Interrogating the Phylogenomics and Mobilome of Colonizing Multidrug Resistant Organisms (MDROs) in Hospitalized Patients and Community-Dwellers in Pakistan”

September

• Daved Fremont, PhD
  $1.39M from NIH for “B Cell Epitope Discovery and Mechanisms of Antibody Protection”
• Jonathan Kipnis, PhD
  $249,999 from Carol and Gene Ludwig Family Foundation for “Exhibit B-3 Meningeal lymphatic vessels in Alzheimer’s disease”
• Nima Mosammaparast, MD, PhD
  $45,000 from NIH for “Structural Cell Biology of DNA Repair Machines”

October

• Kathleen Sheehan, PhD
  $300,000 from NGM Biopharmaceuticals for “Elucidating the Role of LAIR1 in Controlling Tumor Immunity”

November

• Gautam Dantas, PhD
  $123,589 from bioMerieux for “Validation of bioMerieux EPISEQ CS and EPISEQ 16S using Wash U whole bacterial genomes and metagenomics 16S rRNA gene sequence databases”
• Takeshi Egawa, MD, PhD
  $78,750 from NIH for “Developing tools to study relationship between oxidative stress in T cell dysfunction”
• Jeffrey Gordon, MD
  $824,113 from Bill & Melinda Gates Foundation for “Maternal Microbiome directed therapeutic foods development”

December

• Ali Ellebedy, PhD
  $735,765 from Moderna Therapeutics for “Defining the Cross-Reactivity and Durability of Human B Cell Responses to SARS-CoV-2 Variants-Based mRNA Vaccination”
  $1.13M from Moderna Therapeutics for “Defining the Diversity and Specificity of Human B Cell Response to Influenza Virus mRNA-Based Vaccines”
• Scott Handley, PhD
  $52,838 from The Leona M. and Harry B. Helmsley Charitable Trust for “Anti-phage Antibodies in Stratifying Crohn’s Disease Diagnosis and Treatment Response”
• Jonathan Kipnis, PhD
  $172,500 from Cure Alzheimer’s Fund for “Contribution of skull bone marrow-derived cells to Alzheimer’s disease”
  $300,000 from anonymous foundation for “Contribution of skull bone marrow-derived cells to Alzheimer’s disease”