Publications

Please see below for recent publications from members of our department.

• Engineered Escherichia coli Nissle with an inducible phenylalanine degrading cassette and a multi-input kill switch

  December 25, 2026

  Engineered Escherichia coli Nissle with an inducible phenylalanine degrading cassette and a multi-input kill switch

  Evbuomwan, E. M., Khanna, S., Xi, C., Rottinghaus, A. G., Ferreiro, A., Kwak, S., Butler, B., Ning, J., Najari, J., Liao, J., Diao, H., Moon, T. S. & Dantas, G., Dec 25 2026, In: New Biotechnology. 96, p. 86-96 11 p.

  Research output: Contribution to journal › Article › peer-review

  Publication

• CSF1R regulates monocyte subset differentiation and intracellular metabolism

  December 1, 2026

  CSF1R regulates monocyte subset differentiation and intracellular metabolism

  Gallerand, A., Merlin, J., Caillot, Z., Delaby, C., Bord, E., Han, J., Dolfi, B., Chang, M. D., Thierry, G. R., Castiglione, A., Grenet, S., Goës, E., Franceschini, M., Jarretou, G., Zair, F. N., Boré, E., Tuffin, F., Dombrowicz, D., Chinetti, G. & Guinamard, R. R. & 12 others, Artyomov, M. N., Wakkach, A., Pisani, D. F., Randolph, G. J., Bertola, A., Auberger, P., Jacquel, A., Hume, D. A., Williams, J. W., Bajénoff, M., Neels, J. G. & Ivanov, S., Dec 2026, In: Nature communications. 17, 1, 8315.

  Research output: Contribution to journal › Article › peer-review

  Publication

• Proteomic profiling reveals age-related changes in transporter proteins in the human blood–brain barrier

  December 1, 2026

  Proteomic profiling reveals age-related changes in transporter proteins in the human blood–brain barrier

  Zhou, X., Azimi, M., Handin, N., Riselli, A., Vora, B., Chun, E., Dang, Z., Huang, E., Yee, S. W., Artursson, P. & Giacomini, K. M., Dec 2026, In: Scientific reports. 16, 1, 1698.

  Research output: Contribution to journal › Article › peer-review

  Publication

• Transplantation of human iPSC-derived microglia ameliorates neuropathology and circuit dysfunction in progranulin-deficient mice

  December 1, 2026

  Transplantation of human iPSC-derived microglia ameliorates neuropathology and circuit dysfunction in progranulin-deficient mice

  Davtyan, H., Naguib, S., Voskobiynyk, Y., Chadarevian, J. P., Capocchi, J. K., Giacchino, J. L., Eskandari-Sedighi, G., DeNittis, V., Ford, J. B., Agababian, A., Nguyen, J., Chadarevian, A. L., Sutherland, M. S., Shabestari, S. K., Tran, K., Holt, B., Nana, A. L., Zhang, J., Spina, S. & Wong, M. Y. & 9 others, Grinberg, L. T., Seeley, W. W., Huang, E., Clelland, C. D., Gong, S., Fan, L., Paz, J. T., Blurton-Jones, M. & Gan, L., Dec 2026, In: Molecular neurodegeneration. 21, 1, 64.

  Research output: Contribution to journal › Article › peer-review

  Publication

• Validation of a tissue-based predictive RNA test for immunotherapy benefit in NSCLC: the PREDAPT study

  December 1, 2026

  Validation of a tissue-based predictive RNA test for immunotherapy benefit in NSCLC: the PREDAPT study

  Flanagan, K. C., Earls, J., Hiken, J., Wellinghoff, R. L., Ponder, M. M., Pemberton, K., Macdonald, O. K., Welaya, K., Pippas, A. W., D’Silva, K., Sui, X., Alexander, W. L., Slim, J., Saccaro, S. J., Shenkenberg, T. D., Bailey, S. D., Sonnier, S. A., Azzi, G., Bank, B. & Kossman, S. E. & 6 others, Gonzales, P., Wade, J., Hellyer, J. A., McLeod, H. L., Duncavage, E. J. & Glasscock, J. I., Dec 2026, In: npj Precision Oncology. 10, 1, 369.

  Research output: Contribution to journal › Article › peer-review

  Publication

• Broadly reactive human monoclonal antibodies targeting influenza a nucleoprotein lack protective activity in vivo

  December 1, 2026

  Broadly reactive human monoclonal antibodies targeting influenza a nucleoprotein lack protective activity in vivo

  Harrington, W. N., Brice, D. C., Schmitz, A. J., Turner, J., Brent, R., Mudd, P., Ellebedy, A. H. & Webby, R. J., Dec 2026, In: Scientific reports. 16, 1, 27561.

  Research output: Contribution to journal › Article › peer-review

  Publication

• A computational model to describe multi-regional brain architecture during neurodegeneration in Alzheimer’s disease

  December 1, 2026

  A computational model to describe multi-regional brain architecture during neurodegeneration in Alzheimer’s disease

  Alzheimer’s Disease Neuroimaging Initiative (ADNI) & Australian Imaging Biomarkers and Lifestyle (AIBL) Study, Dec 2026, In: Scientific reports. 16, 1, 27168.

  Research output: Contribution to journal › Article › peer-review

  Publication

• SHIP1 is required for T cell surveillance of occult malignancies

  December 1, 2026

  SHIP1 is required for T cell surveillance of occult malignancies

  Fernandes, S., Srivastava, N., Pedicone, C., Sudan, R., Engelman, R. W. & Kerr, W. G., Dec 2026, In: Cellular and Molecular Life Sciences. 83, 1, 352.

  Research output: Contribution to journal › Article › peer-review

  Publication

• Infectious complications in kidney transplant recipients across Africa: a scoping review of epidemiology, microbiology, and prophylaxis strategies

  December 1, 2026

  Infectious complications in kidney transplant recipients across Africa: a scoping review of epidemiology, microbiology, and prophylaxis strategies

  Arthur, S. E., Sankofi, A. M., Laryea, M. N. A. A., Owusu, R., Aboagye, J. O., Omosule, C. L. & Kyei, G. B., Dec 2026, In: BMC Infectious Diseases. 26, 1, 1818.

  Research output: Contribution to journal › Review article › peer-review

  Publication

• Distinct molecular subgroups in pediatric and young-onset meningiomas require age-adapted risk stratification

  December 1, 2026

  Distinct molecular subgroups in pediatric and young-onset meningiomas require age-adapted risk stratification

  Berghaus, N., Tauziède-Espariat, A., Hielscher, T., Savran, D., Schrimpf, D., Göbel, K., Stutheit-Zhao, E., Friedrich, L., Keller, F., Aras, F. K., Nozzoli, F., Sturm, D., White, C. L., Schmid, S., Mawrin, C., Neumann, J. E., Acker, T., Beschorner, R., Hartmann, C. & Saribiyik, I. & 28 others, Inan, A., Erşen-Danyeli, A., Kranendonk, M. E. G., Maas, S. L. N., Bos, E. M., Aronica, E., Peerdeman, S. M., Thuijs, N. B., Mühlebner, A., Kusters, B., den Dunnen, W. F. A., Lavarino, C. E., Puget, S., Chiang, J., Dahiya, S., Pekmezci, M., Perry, A., Akanji, O., Ratliff, M., Herold-Mende, C., Krieg, S. M., Wick, W., Pfister, S. M., Wesseling, P., von Deimling, A., Varlet, P., Sahm, F. & Sievers, P., Dec 2026, In: Nature communications. 17, 1, 6188.

  Research output: Contribution to journal › Article › peer-review

  Publication

• An Agreement Study of Stromal Cellularity, Stromal Cell Atypia, and Tumor Border of Phyllodes Tumors of the Breast

  November 1, 2026

  An Agreement Study of Stromal Cellularity, Stromal Cell Atypia, and Tumor Border of Phyllodes Tumors of the Breast

  Li, X., Haw, Y., Liu, Y., Iqbal, J., Ahmed, S. S., Guo, H., Wei, S., Yasmeen, S., Ye, J., Hou, Y., Eshraghi, R., Zhang, H., Ai, D., Zhang, G., Nayak, A., Jalali Farahani, S., Rosa, M., Zhan, H., Buttars, P. & Bakkar, R. & 8 others, Schnitt, S., Brogi, E., Allison, K., Collins, L. C., Sahin, A., Siziopikou, K. P., Chen, Y. Y. & Khoury, T., Nov 2026, In: Modern Pathology. 39, 11, 101079.

  Research output: Contribution to journal › Article › peer-review

  Publication

• Current status of genetic testing and mosaic variant assessment in somatic overgrowth and vascular anomalies: Insights from the Cancer Genomics Consortium Working Group

  November 1, 2026

  Current status of genetic testing and mosaic variant assessment in somatic overgrowth and vascular anomalies: Insights from the Cancer Genomics Consortium Working Group

  Dharmadhikari, A. V., Myers, C. T., King, K. A., Mojarad, B., Claire Hou, Y. C., Liu, J., Hernandez, P. V., Surrey, L. F., Fisher, K. E., Hammill, A., Adams, D., Paschal, C., Phung, T. L., Cottrell, C. & Cao, Y., Nov 2026, In: Genetics in Medicine. 28, 11, 102686.

  Research output: Contribution to journal › Review article › peer-review

  Publication

• Utility of the SCVP consensus statement of temporal artery biopsy for arteritis

  November 1, 2026

  Utility of the SCVP consensus statement of temporal artery biopsy for arteritis

  Duan, X., Bernadt, C. T., Ritter, J. H. & Lin, C. Y., Nov 1 2026, In: Cardiovascular Pathology. 85, 107850.

  Research output: Contribution to journal › Article › peer-review

  Publication

• SNX17 facilitates entry and infection of Rift Valley fever virus and related bunyaviruses

  October 27, 2026

  SNX17 facilitates entry and infection of Rift Valley fever virus and related bunyaviruses

  Ganaie, S., Fatma, F., Hu, Z., Grodzki, M., Rush, R. E., Clees, J., Brown, G., Barreca, O., Cui, X., Cho, B. K., Goo, Y. A., Hartman, A. L., Leung, D. & Amarasinghe, G. K., Oct 27 2026, In: Cell Reports. 45, 10, 118082.

  Research output: Contribution to journal › Article › peer-review

  Publication

• Somatic mutations reveal the ontogeny of microglia in human ageing

  October 22, 2026

  Somatic mutations reveal the ontogeny of microglia in human ageing

  Belk, J. A., Zhang, Y., Reilly, E. E., Shi, Q., Liu, D. D., Womack-Gambrel, N., van der Linde, M., Ma, L., Paul, D., Enciso, A. M., Kalluru, R., Weiss, J., Li, R., Eastman, A. E., Zhu, C., Chakravarthy, A., Bukhari, S., Bhattacharya, D., Raj, S. & Richard, D. & 26 others, Brioschi, S., Chrostek, M. R., Nachun, D. C., Arends, C. M., Gopakumar, J., Tengesdal, I. W., Bynum, A., Mitchell, S., Sandor, K., Zhang, W., Vardarajan, B. N., Cobos, I., Born, D. E., West, R. B., Brunet, A., Colonna, M., Bharani, K. L., Vogel, H., Montine, T. J., Latimer, C. S., Weissman, I. L., Matusiak, M., Hooper, J. E., Keene, C. D., Chang, H. Y. & Jaiswal, S., Oct 22 2026, In: Nature. 658, 8137, p. 963-971 9 p.

  Research output: Contribution to journal › Article › peer-review

  Publication

• Epidemiologic Study of Transfusion-Related Alpha-Gal Syndrome

  October 5, 2026

  Epidemiologic Study of Transfusion-Related Alpha-Gal Syndrome

  Kaufman, R. M., Hoen, A. G., Khan, J., Knudson, C. M., Metcalf, R. A., Mindiola Romero, A. E., Mo, A., Schäfer, R., Takanashi, M., Dunbar, N. M., Afraz, S., Allen, E. S., Andrews, J., Aurich, K., Casey, J., Cohn, C. S., Cone Sullivan, J. K., Cousins, C. C., Crowe, E. P. & De Giorgi, V. & 35 others, Delaney, M., Delbaugh, R. M., Gilstad, C. W., Gofton, A., Hendrickson, J. E., Hill, K., Hogan, K. O., Humbrecht, C., Ikeda, K., Jacquot, C., Javanbakht, A., Juskewitch, J. E., Lu, W., Menzies Wojtowicz, M. M., Miller, M. J., Mills, G., Nelson, A. C., Pagano, M. B., Pauly, M. C., Poisson, J. L., Raval, J. S., Saifee, N. H., Samy, N., Sato, T., Takeda, Y., Thibodeaux, S. R., Tiberghien, P., Van Nunen, S., Virk, M. S., West-Mitchell, K., Wood, E. M., Yamanouchi, J., Yoshihara, S., Zheng, X. L. & Ziman, A., Oct 5 2026, In: JAMA Internal Medicine. 186, 10, p. 1202-1211 10 p.

  Research output: Contribution to journal › Article › peer-review

  Publication

• ID2 secures cDC1 specification by antagonizing E proteins at a pleiotropic Zeb2 enhancer

  October 1, 2026

  ID2 secures cDC1 specification by antagonizing E proteins at a pleiotropic Zeb2 enhancer

  Ou, F., Liu, T., Du, S., Chen, J., Kraft, M., Nam, G., Bhattarai, B., Shin, H., Koch, A. R., Murphy, T. L. & Murphy, K. M., Oct 2026, In: Nature immunology. 27, 10, p. 2043-2057 15 p.

  Research output: Contribution to journal › Article › peer-review

  Publication

• High-grade astrocytoma with piloid features: A clinical and genomic analysis of prognostic factors using a large cohort

  October 1, 2026

  High-grade astrocytoma with piloid features: A clinical and genomic analysis of prognostic factors using a large cohort

  Zhang, S., Singh, O., Dazelle, K., Quezado, M., Cimino, P. J., Abdullaev, Z., Wu, J., Lucas, C. H., Schreck, K. C., Holdhoff, M., Pytel, P., Goodwill, V., Macaulay, R., McDonald, W., Seidman, R., Wood, M., Bharani, K., Neltner, J., Richard, H. & Chang, K. & 62 others, Szymanski, L., Yip, S., Mukherjee, A., Lopes Abath Neto, O., Sharma, S. J., Green, R., Brown, D., Gubbiotti, M. A., Ballester, L. Y., Eschbacher, J., Smith-Cohn, M., Gokden, M., Vincentelli, C., Yong, W., Lee, J., Mount, C., Fulmer, J., Sun, M., Ligon, K., Santi, M., Pai, E. L. L., Yeaney, G., Alexandrescu, S., Raghavan, R., Fernandes, I., Reis, G. F., Mandel, J., Caccamo, D., Rao, S., Butt, O. H., Dahiya, S., Stone, S., Conway, K., Nasrallah, M. P., Fuller, C., Toland, A., Lukas, R. V., Cachia, D., Uhlmann, E. J., McCord, M., Helgager, J., Han, K., Perry, A., Perez, S., Daoud, E., BeDell, D., Highfield, H., Kobalka, P., Nix, J. S., Nduom, E., Neill, S., Gilbert, M. R., Lakis, N., Fonseca, A., Shen, C., Yoda, R., Monterroza, L., Cohen, A. L., Cathcart, S., Al Amin, M., Campian, J. & Aldape, K., Oct 2026, In: Neuro-oncology. 28, 10, p. 2435-2448 14 p.

  Research output: Contribution to journal › Article › peer-review

  Publication

• Study of blood linear RNA nominates CD55 and DLD as early-stage biomarkers for Parkinson's disease

  October 1, 2026

  Study of blood linear RNA nominates CD55 and DLD as early-stage biomarkers for Parkinson’s disease

  Beric, A., Sahin, S., Sanchez, S., Yang, Z., Kumar, R., Alfradique-Dunham, I., Sanford, J., Western, D., Phillips, B., Budde, J. P., Perrin, R., Kotzbauer, P. T., Perlmutter, J. S., Norris, S., Cruchaga, C. & Ibanez, L., Oct 2026, In: Brain. 149, 10, p. 3509-3523 15 p.

  Research output: Contribution to journal › Article › peer-review

  Publication

• Antisense Oligonucleotide Tofersen Distribution in the Central Nervous System of <em>SOD1</em>-ALS Autopsy Tissue Donors

  September 14, 2026

  Antisense Oligonucleotide Tofersen Distribution in the Central Nervous System of SOD1-ALS Autopsy Tissue Donors

  Guise, A. J., Sellon, M. T., Roemer, S. F., Monine, M., Comfort Harris, N. T., Bartlett, D., David, E., Xu, S., Jandreski, L., Malek, S., Garafalo, S., Nestorov, I., Ireland, M. D., King, A., Bowser, R. P., Korben, V. A., Ravits, J., Shaw, P. J., Highley, J. R. & Ferguson, T. A. & 15 others, Fradette, S., Graham, D. L., Sorenson, E. J., Oskarsson, B., Reichard, R. R., Dickson, D. W., Paganoni, S., Babu, S., Oakley, D. H., Frosch, M. P., Miller, T., Bucelli, R. C., Perrin, R., Ly, C. & Plowey, E. D., Sep 14 2026, In: JAMA Neurology. 83, 9, p. 884-893 10 p.

  Research output: Contribution to journal › Article › peer-review

  Publication