Publications

Please see below for recent publications from members of our department.

• Dual orexin receptor antagonism with lemborexant enhances microglial clearance of β-amyloid in mice

  December 1, 2026

  Dual orexin receptor antagonism with lemborexant enhances microglial clearance of β-amyloid in mice

  Sharma, A., Segawa, E., Chen, X., Park, S., Wang, S., Irmen, R. E., Constantino, N. J., Wang, C., Kanan, M. F., Colonna, M., Macauley, S. L., Cheng, J. Y., Hatanaka, K., Moline, M. & Musiek, E. S., Dec 2026, In: Molecular neurodegeneration. 21, 1, 28.

  Research output: Contribution to journal › Article › peer-review

  Publication

• Optical coherence tomography enables optical biopsy of endometrial tissue for early cancer detection

  December 1, 2026

  Optical coherence tomography enables optical biopsy of endometrial tissue for early cancer detection

  Thakur, S., Lin, Y., Xu, J., Nie, H., Badwan, S., Wang, L., Sanders, B., Thaker, P. H., Hagemann, A. R., McCourt, C., Khabele, D. M., Powell, M., Mutch, D. G., Kuroki, L. M., Hagemann, I. S. & Zhu, Q., Dec 2026, In: NPJ Imaging. 4, 1, 39.

  Research output: Contribution to journal › Article › peer-review

  Publication

• A case of Heart Transplant After Bartonella henselae Infective Endocarditis Associated with an Implantable Cardioverter-Defibrillator

  December 1, 2026

  A case of Heart Transplant After Bartonella henselae Infective Endocarditis Associated with an Implantable Cardioverter-Defibrillator

  Chen, M. Z., Vasiloudes, K. P., Flores, J. M., Gaut, J. P. & Czapka, M. T., Dec 2026, In: SN Comprehensive Clinical Medicine. 8, 1, 175.

  Research output: Contribution to journal › Article › peer-review

  Publication

• Three-dimensional ex-vivo visualization of normal and inflamed small intestine and colonic tissue using optical coherence tomography

  December 1, 2026

  Three-dimensional ex-vivo visualization of normal and inflamed small intestine and colonic tissue using optical coherence tomography

  Matt, A., Li, Y., Song, A., Nix, B. D., Huang, K., Jain, U., Ma, C., Zhou, C. & Deepak, P., Dec 2026, In: Scientific reports. 16, 1, 15568.

  Research output: Contribution to journal › Article › peer-review

  Publication

• Electron microscopy visualization of cell-free mitochondrial DNA-associated vesicular structures in human plasma, serum, and saliva

  November 1, 2026

  Electron microscopy visualization of cell-free mitochondrial DNA-associated vesicular structures in human plasma, serum, and saliva

  Volos, A., Franklin, S. G., Michelson, J., Rausser, S., Brestoff, J. R. & Picard, M., Nov 2026, In: Mitochondrion. 91, 102169.

  Research output: Contribution to journal › Article › peer-review

  Publication

• Direct-to-definitive urine drug screening in children unmasks false-negative immunoassay screening

  September 15, 2026

  Direct-to-definitive urine drug screening in children unmasks false-negative immunoassay screening

  Lin, Y., El-Khoury, J. M., Garg, U. C., Jones, P. M., Lo, S. F., Patel, K., Roper, S. M. & Dietzen, D., Sep 15 2026, In: Clinica Chimica Acta. 591, 121136.

  Research output: Contribution to journal › Article › peer-review

  Publication

• Biophysical Characterization of Ebola VP35 Protein Binding to Host Mindbomb Protein 2

  September 1, 2026

  Biophysical Characterization of Ebola VP35 Protein Binding to Host Mindbomb Protein 2

  Kuang, X. C., Uwase, G., Wagner, N. D., Gross, M. L., Leung, D. W. & Amarasinghe, G. K., Sep 1 2026, In: Journal of Molecular Biology. 438, 17, 169875.

  Research output: Contribution to journal › Article › peer-review

  Publication

• Immune cells in cardiac homeostasis and disease

  September 1, 2026

  Immune cells in cardiac homeostasis and disease

  Axelrod, M. L., Lavine, K. & Lin, C.-Y., Sep 1 2026, In: Cardiovascular Pathology. 84, 107835.

  Research output: Contribution to journal › Review article › peer-review

  Publication

• Validating a Human Cell Model of Null Galactosylceramidase (GALC) Enzyme Activity That Recapitulates Krabbe Disease

  July 1, 2026

  Validating a Human Cell Model of Null Galactosylceramidase (GALC) Enzyme Activity That Recapitulates Krabbe Disease

  Starosta, R. T., Khatoon, N., Roberts, M. S., Le, S. Q., Austin, G., Cui, X., Strout, G., Schmidt, R., Jiang, X., Sands, M. & Dickson, P. I., Jul 2026, In: Journal of Inherited Metabolic Disease. 49, 4, e70212.

  Research output: Contribution to journal › Article › peer-review

  Publication

• R17 Drives Heparan Sulfate Clearance via Endolysosomal Trafficking

  July 1, 2026

  R17 Drives Heparan Sulfate Clearance via Endolysosomal Trafficking

  Bedekar, P., Lin, A., Reeves, A. E., Critcher, M., Yang, G. S., Hui, S., Fremont, D. H. & Huang, M. L., Jul 2026, In: Israel Journal of Chemistry. 66, 4, e70016.

  Research output: Contribution to journal › Article › peer-review

  Publication

• Diagnostic and therapeutic applications of the glycan biomarker H3N2b in GM1 Gangliosidosis

  July 1, 2026

  Diagnostic and therapeutic applications of the glycan biomarker H3N2b in GM1 Gangliosidosis

  Kell, P., Mishra, S., D’Souza, P., Tifft, C. J., Dietzen, D. J., Lasio, L. D., Carson, J. P., Hong, X., Schiffmann, R., Ledesma, M. D., Tayebi, N., Dickson, P. I., Porter, F. D., Ory, D. S. & Jiang, X., Jul 2026, In: Molecular genetics and metabolism. 148, 3, 110159.

  Research output: Contribution to journal › Article › peer-review

  Publication

• Neuronal responses to cytokines limit intestinal hypermotility and systemic effects of colonic inflammation

  June 19, 2026

  Neuronal responses to cytokines limit intestinal hypermotility and systemic effects of colonic inflammation

  Jung, J., Wehmeier, A., Xie, Z., Horton, D., Russler-Germain, E. V., Schill, E. M., Miller, M., Brestoff, J. R., Newberry, R., Kim, B., Hu, H. & Hsieh, C., Jun 19 2026, In: iScience. 29, 6, 116291.

  Research output: Contribution to journal › Article › peer-review

  Publication

• Reply to Wang et al. Linking microbial metabolites and gut epithelial responses to microbiome-directed therapeutic foods

  June 16, 2026

  Reply to Wang et al. Linking microbial metabolites and gut epithelial responses to microbiome-directed therapeutic foods

  Wang, Y., Chang, H.-W., Barratt, M. J. & Gordon, J., Jun 16 2026, In: Proceedings of the National Academy of Sciences of the United States of America. 123, 24, e2613406123.

  Research output: Contribution to journal › Letter › peer-review

  Publication

• Tumor-draining lymph nodes in ovarian cancer lack germinal centers but harbor tumor-reactive memory B cells clonally linked to intra-tumoral B cells

  June 9, 2026

  Tumor-draining lymph nodes in ovarian cancer lack germinal centers but harbor tumor-reactive memory B cells clonally linked to intra-tumoral B cells

  Nathan, N., Paparoditis, P., Sarusi-Portuguez, A., Stoler-Barak, L., Horn, H. M., Milo, I., Mazor, R. D., Levy-Barda, A., Yanichkin, N., Borcherding, N., Blecher-Gonen, R., Ronen, R., Nachman, I. B., Goliand, I., Fellus-Alyagor, L., Salame, T. M., Sagi, I., Siloni, G. H., Gross, M. & Tenenbaum, A. & 5 others, Kent, I., Keren, L., Raban, O., Eitan, R. & Shulman, Z., Jun 9 2026, In: Immunity. 59, 6, p. 1743-1757.e10

  Research output: Contribution to journal › Article › peer-review

  Publication

• Case Report: Synchronous Manifestations of Kaposi Sarcoma Herpesvirus-Associated Disorders

  June 1, 2026

  Case Report: Synchronous Manifestations of Kaposi Sarcoma Herpesvirus-Associated Disorders

  Roberts, K., Valiño Ramos, P., Jindal, S., Prasad, V., Lee, Y.-S., Khanfar, M., Griffith, O., Griffith, M., Jiang, J., Cesarman, E., Rauch, D., Simonson, P., Odeny, T. & Ratner, L., Jun 2026, In: Cancer Reports. 9, 6, e70589.

  Research output: Contribution to journal › Article › peer-review

  Publication

• Astrocytic cholesterol jams brain clearance in AD

  June 1, 2026

  Astrocytic cholesterol jams brain clearance in AD

  Verhaege, D. & Kipnis, J., Jun 2026, In: Nature neuroscience. 29, 6, p. 1272-1274 3 p.

  Research output: Contribution to journal › Comment/debate

  Publication

• Inter-Instrument Imprecision Complements Bias in Evaluating LDL-C Method Performance

  June 1, 2026

  Inter-Instrument Imprecision Complements Bias in Evaluating LDL-C Method Performance

  Huggler, K. S., Mensah, I. K., Dajles, A. D., Roper, S. M. & Farnsworth, C. W., Jun 2026, In: Clinical chemistry. 72, 6, p. 703-704 2 p.

  Research output: Contribution to journal › Letter › peer-review

  Publication

• Proactive identification of candidates for newly approved targeted therapies using a clinical decision support program

  June 1, 2026

  Proactive identification of candidates for newly approved targeted therapies using a clinical decision support program

  Feldman, R., Abdulla, F., Hinton, A., Hamrick, J., Hill, B., Fernandez, J., Walton, A., Shah, N., Appleberry, G., El Shawa, H., Sheridan, R. L., Geist, B. M., Coleman, J., Duncavage, E., Arnal, S., Vacirca, J. & Holloway, J., Jun 2026, In: Oncologist. 31, 6, oyag169.

  Research output: Contribution to journal › Article › peer-review

  Publication

• A Matter of Comparison: Hematocrit Measurement

  June 1, 2026

  A Matter of Comparison: Hematocrit Measurement

  Morse, P. & Jackups, R., Jun 2026, In: Clinical chemistry. 72, 6, p. 707-708 2 p.

  Research output: Contribution to journal › Article › peer-review

  Publication

• Challenges in identifying HER2-low metastatic breast cancer: Real-world perspectives from a nationwide pathologist survey.

  June 1, 2026

  Challenges in identifying HER2-low metastatic breast cancer: Real-world perspectives from a nationwide pathologist survey.

  Meisel, J. L., Sidiropoulos, N., Hagemann, I. S., Valla, K., Anderson, C., Alexander, C., Dooyema, S., Carter, J. D., Heggen Ladda, C. & McKinnon, K. E., Jun 2026, In: Journal of Clinical Oncology. 44, 16, p. e13138-e13138

  Research output: Contribution to journal › Article › peer-review

  Publication