Liang-I Kang, MD, PhD

Liang-I Kang, MD, PhD

Instructor, Anatomic and Molecular Pathology


  • Anatomic & Molecular Pathology

Additional Titles

  • Instructor, Anatomic & Molecular Pathology


  • BS Biological Sciences, Minor in Chemistry: University of Delaware, Newark, DE (2002-2006)
  • PhD Cellular and Molecular Pathology: University of Pittsburgh School of Medicine, Pittsburgh, PA (2006-2013)
  • MD: University of Pittsburgh School of Medicine, Pittsburgh, PA (2006-2014)
  • Anatomic Pathology Residency – WashU/BJH/SLCH Consortium Residency Program, St. Louis, MO (2015-2018)
  • Liver and Gastrointestinal Pathology Clinical Fellowship, Washington University in St. Louis School of Medicine (2018-2019)


  • University of Delaware Scholar Award (2002)
  • Women of Promise Distinction Award, University of Delaware (2003)
  • Barry M. Goldwater Scholar Award, Barry Goldwater Scholarship and Excellence in Education Foundation (2004)
  • Beckman Scholar Award, Arnold and Mabel Beckman Foundation (2004) 
  • Richard M. Johnson Memorial Award, University of Delaware (2005)
  • AAAS Student Poster Competition Winner for the Molecular and Cellular Biology category (2006)
  • AAUP Undergraduate Student Award (2006)
  • American Society for Clinical Pathology Award for Academic Excellence and Achievement (2008)
  • Pre-doctoral Fellowship in Clinical and Translational Research, University of Pittsburgh CTSI (Mentors: Wendy Mars, PhD and David Geller, MD; 2009-2011)
  • A.D. Sobel – ASIP Education Fund Trainee Travel Award (2011)
  • ASIP Marcos Rojkind Travel Award (2013)
  • MSTP Service Award, University of Pittsburgh Medical Scientist Training Program (2014)
  • Resident of the Month, WashU/BJH/SLCH Consortium Residency Program (2016)
  • Anatomic Pathology Co-Chief Resident, WashU/BJH/SLCH Consortium Residency Program (2017-2018)
  • AP Trainee of the Month, WashU/BJH/SLCH Consortium Residency Program (2019)
  • Postdoctoral Fellow in Training Opportunities in Translational Imaging Education and Research (TOP-TIER T32), Washington University School of Medicine Mallinckrodt Institute of Radiology (2019-2021)
  • K12 Paul Calabresi Career Development Award in Clinical Oncology (2023)

Board Certifications

  • Board Certification in Anatomic Pathology, American Board of Pathology

Honor Society Memberships

  • Member, American Society for Investigative Pathology, 2008-present
  • Member, United States and Canadian Academy of Pathology, 2015-present
  • Associate Member, Hans Popper Hepatopathology Society, 2017-present
  • Associate Member, Rodger C. Haggitt Gastrointestinal Pathology Society, 2017-present
  • Associate Member, Pancreatobiliary Pathology Society, 2018-present

Clinical Interests

  • Hepatobiliary, Pancreatic, and Gastrointestinal Pathology

Research Interests

Pre-metastatic niche of liver metastasis, tumor microenvironment, liver metastasis risk factors, liver injury and fibrosis, pancreatic cancer, GI malignancies, deep learning algorithms, image analysis

Selected Publications

Kang, L.I., Wang, Y., Suckow, A.T., Czymmek, K.J., Cooke, V.G., Naik, U.P., Duncan, M.K. Deletion of JAM-A causes morphological defects in the corneal epithelium. Int. J. Biochem. Cell. Biol. 2007; 39: 576-85. [PMID: 17118692]
Isse, K., Specht, S., Lunz, J.G. III, Kang, L.I., Mizuguchi, Y., Demetris, A.J. Estrogen stimulates female biliary epithelial cell IL-6 expression in mice and humans. Hepatology. 2010; 51(3): 869-80. [PMID: 20043322]
Norris C.A., He M., Kang L.I., Ding M.Q., Radder J.E., Haynes M.M., Yang Y., Paranjpe S., Bowen W.C., Orr A., Michalopoulos G.K., Stolz D.B., Mars W.M. (2014) Synthesis of IL-6 by Hepatocytes Is a Normal Response to Common Hepatic Stimuli. PLoS ONE. 9(4): e96053. [PMID: 24763697] *co-first authors
Kang, L.I., Isse, K., Koral, K., Bowen, W.C., Muratoglu, S.C., Strickland, D.K., Michalopoulos, G.K, Mars, W.M. (2015). Tissue-type plasminogen activator suppresses activated stellate cells through low-density lipoprotein receptor-related protein 1. Lab Invest. 95(10):1117-29. [PMID: 26237273]
Bhatt, N.K., Kang, L.I., El-Mofty, S., Nuseenbaum, B., Pipkorn, P. (2018). Emergent parotidectomy after parotid lymphatic malformation hematoma. Otolaryngology Case Reports. 7: 16-18.
González, I.A., Kang, L.I., Williams, G.A., Liu, J., DeNardo, D.G., Hawkins, W.G., Chatterjee, D. Tumor-Insular Complex in Neoadjuvant Treated Pancreatic Ductal Adenocarcinoma Is Associated With Higher Residual Tumor. Am J Surg Pathol. 2020 Jun;44(6):817-825. [PMID: 32091434]
Alpert, L., Al-Sabti, R., Graham, R.P., Pai, R.K., Gonzalez, R.S., Zhang, X., Smith, V., Wang, H.L., Westbrook, L., Goldblum, J.R., Bakhshwin, A., Shetty, S., Klimstra, D.S., Shia, J., Askan, G., Robert, M.E., Thomas, C., Frankel, W.L., Alsomali, M., Hagen, C., Mostafa, M.E., Feely, M.M., Assarzadegan, N., Misdraji, J., Shih, A.R., Agostini-Vulaj, D., Meis, J.M., Tang, S., Chatterjee, D., Kang, L.I., Hart, J., Lee, S.M., Smith, T., Yantiss, R.K., Hissong, E.M., Gao Z.H., Wu, J., Resnick, M.B., Wu, E.Y., Pai, R.K., Zhao, L., Doyle, L.A., Chopra, S., Panarelli, N.C., Hu, S., Longacre, T.A., Raghavan, S.S., Lauwers, G.Y., Ghayouri, M., Cooper, H.S., Nagarathinam, R., Bellizzi, A.M., Kakar, S., Hosseini, M., Rong, J., Greenson, J.K., Lamps, L.W., Dong, Z., Bronner, M.P. Smooth muscle tumors of the gastrointestinal tract: an analysis of prognostic features in 407 cases. Mod Pathol. 2020 Jul;33(7):1410-1419. [PMID: 32051556]
Winkler, E.S., Bailey, A.L., Kafai, N.M., Nair, S., McCune, B.T., Yu, J., Fox, J.M, Chen, R.E., Earnest, J.T., Keeler, S.P, Ritter, J.H., Kang, L.I., Dort, S., Robichaud, A., Head, R., Holtzman, M.J., Diamond, M.S. SARS-CoV-2 infection of human ACE2-transgenic mice causes severe lung inflammation and impaired function [published online ahead of print, 2020 Aug 24]. Nat Immunol. 2020;10.1038/s41590-020-0778-2. doi:10.1038/s41590-020-0778-2 [PMID: 32839612]
Bailey A.L., Kang L.I., de Assis Barros D’Elia Zanella L.G.F., Silveira C.G.T., Ho Y.L., Foquet L., Bial G., McCune B.T., Duarte-Neto A.N., Thomas A., Raué H.P., Byrnes K., Kallas E.G., Slifka M.K., Diamond M.S. Consumptive coagulopathy of severe yellow fever occurs independently of hepatocellular tropism and massive hepatic injury. Proc Natl Acad Sci U S A. 2020 Dec 22;117(51):32648-32656. doi: 10.1073/pnas.2014096117. Epub 2020 Dec 2. [PMID: 33268494; PMCID: PMC7768776.]
Bigley, T.M., Yang, L. , Kang, L.I., Saenz, J.B., Victorino, F., Yokoyama, W.M. Disruption of thymic central tolerance by infection with murine roseolovirus induces autoimmune gastritis. J Exp Med. 2022 Mar 7;219(3):e20211403. [PMID: 35226043; PMCID: PMC8932538]

Lisa Schreiber
BJCIH Room 3422