Melanie L. Yarbrough, PhD

Associate Professor, Pathology & Immunology
Medical Director, Microbiology, Barnes Jewish Hospital

Additional Titles

  • Director, Medical & Public Health Microbiology Fellowship

Related Links


  • BS Veterinary Biomedical and Clinical Sciences: Texas A&M University, College Station, TX (2004)
  • PhD Microbiology: University of Texas Southwestern Medical Center, Dallas, TX (2009)
  • Fellowship, Clinical Chemistry: Washington University, St. Louis, MO (2015)
  • Fellowship, Clinical Microbiology: Washington University, St. Louis, MO (2017)

Board Certifications

  • Diplomate, American Board of Clinical Chemistry, 2015
  • Diplomate, American Board of Medical Microbiology, 2017


  • Washington University Laboratory and Genomic Medicine Fellow Teacher of the Year
  • American Association for Clinical Chemistry (AACC) Outstanding Speaker Award

Clinical Interests

  • Microbiology
  • Bacteriology
  • Urinary tract infection
  • Sexually transmitted infection
  • Antimicrobial resistance

Research Interests

My research focuses on the evaluation of methods for isolation and identification of urinary pathogens, including multi-drug resistant organisms. Additional studies aim to characterize the urinary microbiome to explore links between characteristic microbial communities and the presence of sexually transmitted infections (STI) and UTI. Together, these studies will provide opportunities for improvement of both diagnostic and antimicrobial stewardship of genitourinary diseases that have a major impact on public health.


PubMed Search

Yarbrough ML, Kwon JH, Wallace MA, Hink T, Shupe A, Fraser VJ, Dubberke ER, Burnham C-AD for the CDC Prevention Epicenter Program. Frequency of instrument, environment, and laboratory technologist contamination during routine diagnostic testing of infectious specimens. J Clin Microbiol. 2018 56(6) (PMID 29679555)
Yarbrough ML, Briden KE, Mitsios JV, Weindel AL, Terrill CM, Hunstad DA, and Dietzen DJ. Mass spectrometric measurement of urinary kynurenine-to-tryptophan ratio in children with and without urinary tract infection. Clinical Biochemistry. 2018 56: 83-88 (PMID 29679555)
Tesfazghi MT, Anderson NW, Gronowski AM, Yarbrough ML. Clinical performance of the BioPlex 2200 Syphilis Total & RPR assay at a tertiary medical center with a high rate of syphilis. J Clin Microbiol. 2018 Nov 14. pii: JCM.01487-18. doi: 10.1128/JCM.01487-18. (PMID 30429251)
Yarbrough ML, Lainhart W, McMullen AR, Anderson NW, MD, Burnham C-AD. Impact of Total Laboratory Automation on Workflow and Specimen Processing Time for Culture of Urine Specimens. Eur J Clin Microbiol Infect Dis. 2018. doi: 10.1007/s10096-018-3391-7 (PMID 30269180)
Yarbrough ML, Lainhart W, Burnham CA. Identification of Nocardia, Streptomyces, and Tsukamurella using MALDI-TOF MS with the Bruker Biotyper. Diagnositic Micobiology and Infectious Disease. 2017. (PMID 28811116)
Yarbrough ML, Wallace MA, Marshall C, Mathias E, Burnham CA. Culture of Urine Specimens Using chromID CPS Elite Medium Can Expedite Escherichia coli Identification and Reduce Hands-On Time in the Clinical Laboratory. J Clin Microbiol. 2016. 54(11): 2767-2773. (PMID 27582518)

Dionne Brierton
BJCIH Room 5800