Ali Ellebedy, PhD

Ali Ellebedy, PhD

Leo Loeb Endowed Professor, Pathology & Immunology

Division

  • Immunobiology

Lab Website

Education

  • BS: Pharmaceutical Sciences, Cairo University School of Pharmacy, Cairo, Egypt (1999-2004)
  • PhD: University of Tennessee Health Science Center, Memphis, TN (2006-2011)

Research Interests

  • Defining the cellular and molecular mechanisms that regulate memory B cell heterogeneity and fate.
  • Understanding the rules for eliciting broadly neutralizing B cell responses against rapidly evolving pathogens, such as influenza viruses.

DBBS Affilation List

  • Immunology
  • Molecular Microbiology
  • Molecular Cell Biology

Selected Publications

Alsoussi WB, Turner JS, Case JB, Zhao H, Schmitz AJ, Zhou JQ, Chen RE, Lei T, Rizk AA, McIntire KM, Winkler ES, Fox JM, Kafai NM, Thackray LB, Hassan AO, Amanat F, Krammer F, Watson CT, Kleinstein SH, Fremont DH, Diamond MS, Ellebedy AH. A Potently Neutralizing Antibody Protects Mice against SARS-CoV-2 Infection. J Immunol. 2020. (https://pubmed.ncbi.nlm.nih.gov/32591393/)
Stadlbauer D, Zhu X, McMahon M, Turner JS, Wohlbold TJ, Schmitz AJ, Strohmeier S, Yu W, Nachbagauer R, Mudd PA, Wilson IA*, Ellebedy AH*, Krammer F*. Broadly protective human antibodies that target the active site of influenza virus neuraminidase. Science. 2019;366(6464):499-504. (https://pubmed.ncbi.nlm.nih.gov/31649200/)
Nachbagauer R, Shore D, Yang H, Johnson SK, Gabbard JD, Tompkins SM, Wrammert J, Wilson PC, Stevens J, Ahmed R, Krammer F*, Ellebedy AH*. Broadly Reactive Human Monoclonal Antibodies Elicited following Pandemic H1N1 Influenza Virus Exposure Protect Mice against Highly Pathogenic H5N1 Challenge. J Virol. 2018;92(16). (https://pubmed.ncbi.nlm.nih.gov/31649200/)

Assistant
Christina Grantham
314-454-8463
granthamc@wustl.edu
Office Location: BJC-IOH Building, Room 11611