Changqing (Cathy) Ma, MD, PhD

Changqing (Cathy) Ma, MD, PhD

Associate Professor, Pathology & Immunology


  • Anatomic & Molecular Pathology


  • MB, Beijing Medical University, Beijing, China
  • PhD, Cellular and Molecular Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA
  • Residency, Washington University School of Medicine, St. Louis, MO
  • Fellowship, Gastrointestinal and Liver Pathology, Johns Hopkins University School of Medicine, Baltimore, MD


  • Gastrointestinal, pancreatobiliary, and liver pathology

Board Certification

  • The American Board of Pathology (ABP) Certification in Anatomic Pathology (AP) and Clinical Pathology (CP)

Clinical Interests

  • Gastrointestinal pathology
  • Pancreatobiliary pathology
  • Liver pathology

Research Interests

The overarching goal of my research is to harness genetics in studying GI inflammatory and neoplastic diseases.

Selected Publications

Ma C, Lowenthal BM, and Pai RK. SATB2 is superior to CDX2 in distinguishing signet ring cell carcinoma of the upper gastrointestinal tract and lower gastrointestinal tract. Am J Surg Pathol. 2018, 42(12):1715-1722. Corresponding author. PMID: 30212392
Gozález I, Goyal B, Xia MD, Pai RK, and Ma C. DNA mismatch repair deficiency but not ARID1A loss is associated with improved prognosis in small intestinal adenocarcinoma. Human Pathol. 2019, 85:18-26. PMID: 30381262
Ma C, Olevian D, Miller C, Herbst C, Jayachandran P, Kozak MM, Chang DT, and Pai RK. SATB2 and CDX2 are prognostic biomarkers in DNA mismatch repair protein deficient colon cancer. Mod Pathol. 2019, 32(8):1217-1231. PMID: 30962505
Ma C, Henn P, Miller C, Herbst C, Hartman DJ, and Pai RK. Loss of SATB2 expression is a biomarker of inflammatory bowel disease-associated colorectal dysplasia and adenocarcinoma. Am J Surg Pathol. 2019, 43(10):1314-1322. PMID: 31318711
Lowenthal BM, Nason KS, Pennathur A, Luketich JD, Pai RK, Davison JM, and Ma C. Loss of ARID1A expression is associated with DNA mismatch repair protein deficiency and favorable prognosis in advanced stage surgically resected esophageal adenocarcinoma. Hum Pathol. 2019, 94:1-10. PMID: 31655170
Villatoro TM, Ma C, and Pai RK. SWI / SNF nucleosome complex-deficient colorectal carcinomas have distinct clinicopathologic features. Hum Pathol. 2020, 99:53-61. PMID: 32222462
Trinh VQ, Shi C, and Ma C. Gastric neuroendocrine tumors from long-term proton pump inhibitor users are indolent tumors with good prognosis. Histopathology. 2020, 77(6):865-876. PMID: 32702178
Farhat L, Hartman DJ, Ma C, Celebrezze J, Medich D, Bahary N, Frank M, Pantanowitz L, Pai RK. Intratumoral budding and automated CD8-positive T-cell density in pre-treatment biopsies can predict response to neoadjuvant therapy in rectal adenocarcinoma. Mod Pathol. 2021, 34(1):171-183. PMID: 32661298
Setia N, Wang C, Lager A, Maron S, Shroff S, Arndt N, Peterson B, Kupfer S, Ma C, Misdraji J, Catenacci D, and Hart J. Morphologic and molecular analysis of early-onset gastric cancer. Cancer. 2021, 127(1):103-114. PMID: 33048355
Ma C, Storer C, Chandran U, LaFramboise WA, Frank M, Hartman DJ, Pantanowitz L, Haritunians T, Head R, and Liu TC. Crohn’s disease-associated ATG16L1 T300A genotype is associated with improved survival in gastric cancer. EbioMedicine. 2021, 67:103347. Co-corresponding author. PMID: 33906066

Lisa Schreiber
Office: 314-273-4843
Fax: 314-747-2663
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