Division chief: Charles S. Eby, MD
The Division of Laboratory and Genomic Medicine at Washington University is home to 17 research laboratories that work in broad areas of basic, translational and clinical research.
Genomics and diagnostics
The sequencing of the human genome and the genomes of many pathogens has ushered in the era of genomics in diagnostic clinical medicine. Gene sequencing and microarray technology are now central approaches in diagnostic clinical pathology. We expect the 21st century to bring new clinical tests centered on epigenomics and proteomics, and we plan on being at the forefront of test development and application using these approaches.
In addition, new recombinant antibody technologies will make multiplexed, ultra-sensitive and nanotechnology immuno-based assays possible that will revolutionize the field. Future trainees in laboratory and genomic medicine may expect to further the field of medical laboratory diagnostics in many exciting ways.
Key research areas
Research areas in the division include:
- Immune system development and function
- Pathogenesis of neurodegenerative disorders
- Host-microbe interactions
- Genetic testing for inherited disorders
- Bioinformatics and medical informatics
- Laboratory diagnostics of endocrinology and reproductive physiology
- Genomics in cancer research.
A broad range of flexible training opportunities
The division offers a competitive, three-year residency that integrates clinical training with basic or applied research experience, and clinical fellowships in transfusion medicine, clinical chemistry, clinical microbiology, and molecular pathology.
Our mission is to train the next generation of leaders in academic clinical pathology through excellence in education, clinical care, basic science, and translational research.
The residency and fellowship training programs in the Division of Laboratory and Genomic Medicine integrate strong clinical training with basic science or translational research training. These programs are appropriate for trainees with MD degrees, MD/PhD degrees, and for some programs, PhD degrees.
The underlying goal of all of our training programs is to train the next generation of leaders in academic clinical pathology. To do so, we have designed all of our programs to have the maximum amount of flexibility in clinical and research training so that they can accommodate the very diverse career goals of our trainees. In addition, in some cases, we can combine fellowships to allow trainees to become experts in more than one area of clinical pathology.
All training programs have research components with trainees taking advantage of research opportunities with mentors throughout the School of Medicine and the university as a whole.
In the early 1970s, trainees in laboratory medicine were challenged to integrate new computer technology and automation into the hospital laboratory environment. The results are highly automated, high-throughput medical laboratories operating today.
In the early 1980s, clinical pathologists utilized monoclonal antibody technology originally developed in the basic science laboratory to develop numerous new medical tests in endocrinology, cardiology and oncology.
In the 1990s, the recognition of new pathogens and human identification of the genes associated with disease processes led to the development of new molecular assays to effectively monitor and treat patients.
Learn more about the history of the department.
Division contact information
Division of Laboratory and Genomic Medicine
Department of Pathology and Immunology
660 South Euclid Avenue
Campus Box 8118
St. Louis, MO 63110
BJC Institute of Health (BJCIH) Building
425 South Euclid Avenue
5th floor, Room 5800
St. Louis, MO 63110
Read past LGM newsletters.