Please see below for the latest grants and other notables in the Department of Pathology & Immunology.
January
- Sarah Ackerman, PhD
$70,000 for 2023 NARSAD Young Investigator Grant from Brain & Behavior Research Foundation
February
- Ali Ellebedy, PhD
$3.29 million, multi-year award from NIAID for “Programming Durable Immune Responses To Vaccination” - Scott Handley, PhD
$575,000 from PolyBio Research Foundation for Long COVID research (in collaboration with Yale School of Medicine researchers)
February
- Marco Colonna, MD, Tom Hannan, DVM, PhD
$3.1 million, multi-year award from NIH for “Mucosal Immune Defense Mechanisms of the Urinary Bladder”
March
- Jasmin Herz, PhD
$201,248 from the Cure Alzheimer’s Agency for “Antiviral T cell infiltration to the meninges and brain influences neurodegeneration in Alzheimer’s disease.” - Liang-I Kang, MD, PhD
Recipient of K12 Paul Calabresi Career Development Award in Clinical Oncology - Cathy Ma, MD, PhD
$50,000, one-year Clinical and Translational Research Funding Program (CTRFP) award for “Define the Utility of Autophagy-Associated ATG16L1 T300A Genotype in Prognostic Stratification of Hepatocellular Carcinoma” - Steffen Storck, PhD
$200,000 from the Alzheimer’s Association to study how the systems involved in controlling how fluid flows into, through and out of the brain interact with each other and affect the development of Alzheimer’s disease
April
- Ta-Chiang Liu, MD, PhD
$1,015,114 from Helmsley Charitable Trust for “Cellular biomarkers for pediatric Crohn’s disease” - Steven Van Dyken, PhD
$4.1 million, 5-year grant from NIH for “Defining the role of IL-18 in atopic dermatitis”
May
- Eric Duncavage, MD, David Spencer, MD, PhD
$1,162,416, multi-year grant from NIH for “A Rapid and Comprehensive Approach for Clinical Genomic Profiling in Lung Cancer”
July
- Martina Molgora, PhD
$300,000, 3-year, 2023 AGA-Gastric Cancer Foundation Ben Feinstein Memorial Research Scholar Award in Gastric Cancer from the AGA Research Foundation - Steven Van Dyken, PhD
$427,834, 2-year, R21 grant from NIAID for “Chitin and chitinases in SARS-CoV-2 infection”
August
- Gaya Amaransinghe, PhD
$16.8 million, 5-year, P01 grant renewal from NIAID for “Molecular Mechanisms of Filoviral-host Interactions” - Viviana Simon, MD, PhD, and Ali Ellebedy, PhD
$13 million, 5-year grant from the National Institute of Allergy and Infectious Diseases for “Programming Long-Lasting Immunity to Coronaviruses (PLUTO)” - Xiaoxiao Wan, PhD
$3 million, 5-year R01 award from National Institute of Diabetes and Digestive and Kidney Diseases for “The role of beta-cell crinophagy in generating diabetogenic neoepitopes”
September
- Ta-Chiang Liu, MD, PhD
$2.13 million, 4-year grant from NIH’s National Institute of Diabetes and Digestive and Kidney for “Dietary modulation of Paneth cells”
November
- Ali Ellebedy, PhD
$1.3 million award from the Gates Foundation for “Impact of pre-existing antibodies on durability of B Cell responses”
December
- Takeshi Egawa, MD, PhD and Kenneth Murphy, MD, PhD
$525,256 from NIH for “Molecular mechanisms of CD8 T cell fate decision instructed by cytokine signaling”
January
- Marco Colonna, MD
$172,500 from Cure Alzheimer’s Fund for “Understanding the Role of Natural Ab-Specific B Cell Responses in AD Progression”
$107,258 from Aclaris Therapeutics for “Study of Gut-Selective vs. Systemic Jak Inhibitors in Pre-Clinical Models of IBD” - Kodi Ravichandran, PhD
$583,731 from NIH for “Solute carrier proteins in efferocytosis and inflammation”
$334,393 from NIH for “Mechanisms regulating apoptotic cell clearance in health and disease” - Steven L. Teitelbaum, MD
$457,219 from NIH for “Hepatic steatosis promotes liver metastasis” - Parker Wilson, MD, PhD
$167,826 from NIH for “The Single Cell Landscape of Early Human Diabetic Nephropathy”
February
- Marco Colonna, MD
$624,511 from NIH for “Ontogenetic niche of B cells at the CNS borders in homeostasis, aging and autoimmunity” - Ali Ellebedy, PhD
$354,375 from NIH for “Structural interrogation of vaccine- and infection-induced B cell responses” - Gwendalyn Randolph, PhD
$544,177 from NIH for “Mechanisms that alter lymphatic transport in inflammatory bowel disease” - Emil Unanue, MD
$471,535 from NIH for “ADMR – Autoimmune Diabetes: Macrophage Responses” - Xiaoxiao Wan, PhD
$471,535 from NIH for “Autoimmune Diabetes: Macrophage Responses”
March
- Maxim Artyomov, PhD
$128,178 from Genentech for “Stochastic simulations of TCR-MHC interactions”
$321,271 from Aging Biology Foundation for “Aging Human Tissues Systems Level Dissection of Immune Aging”
$446,357 from Aging Biology Foundation for “Personnel Systems Level Dissection of Human Aging” - Ali Ellebedy, PhD
$148,226 from NIH for “Understanding the Impact of Imprinting and Repeat Antigen Exposure on Durability of Antibody Responses to the Influenza Virus” - Ta-Chiang Liu, MD, PhD
$34,085 from NIH for “Paneth Cell Heterogeneity in Infection and Inflammation”
$160,001 from Interline Therapeutics for “Developing a translational understanding of high impact genetic variants in inflammatory bowel disease” - Bernd H. Zinselmeyer, PhD
$30,000 from Genentech for “Characterizing the impact of CD2AP and CIN85 on Leucocyte motility in real time in vivo”
April
- Gautam Dantas, PhD
$60,000 from The Foundation For Barnes-Jewish Hospital for “CTRFP Strain tracking and genomic characterization of Pseudomonas aeruginosa across clinical and environmental samples in the BJH healthcare system” - Brian Edelson, MD, PhD
$236,250 from NIH for “Selective induction of alloantigen-specific humoral tolerance by MHC-Fc fusion proteins” - Jonathan Kipnis, PhD
$345,000 from Cure Alzheimer’s Fund for “Berg Brain Entry & Exit Consortium: Crosstalk of CNS barriers and clearance routes in homeostasis and Alzheimer’s disease” - Melanie L. Yarbrough, PhD
$110,076 from bioMerieux for “bioMerieux IIR Program”
May
- Marco Colonna, MD
$430,655 from NIH for “Soluble TREM2 regulation of microglial function in Alzheimer disease”
$196,875 from NIH for “Impact of polyamines on ILC3 function at steady state and in preclinical model of colitis” - Brian Edelson, MD, PhD
$176,889 from National Multiple Sclerosis Society for “T cell-intrinsic roles for the ZFP36 family proteins in MS and EAE”
June
- Marco Colonna, MD
$149,999 from Kenneth Rainin Foundation for “How intraepithelial TCRgd T cell subsets maintain intestinal homeostasis” - Brian Edelson, MD, PhD
$319,584 from NIH for “Role of Intestinal Parasites on Regulating Immune Responses to Gut Antigens” - Ta-Chiang Liu, MD, PhD
$149,999 from Kenneth Rainin Foundation for “Autophagy shapes Debaryomyces hansenii invasion in Crohn’s disease” - Kenneth Murphy, MD, PhD
$559,854 from NIH for “Molecular Basis of cDC1 Development” - Steve Persaud, MD, PhD
One-year, $70,000 Developmental Research Program award from the Washington University Specialized Program of Research Excellence (SPORE) in Leukemia for his project entitled: “Maximizing antileukemia effect and minimizing toxicity of antibody-based HSCT conditioning”
July
- Robert Schreiber, PhD
$401,129 from NIH for “Training in the Immunobiology and Molecular Cell Biology of Cancer” - Steven L. Teitelbaum, MD
$1,000 from The Foundation For Barnes-Jewish Hospital for “Avioli Lecture Award”
$39,413 for The Foundation For Barnes-Jewish Hospital for “Sonnenwirth Lecture Award”
August
- Jonathan Kipnis, PhD
$585,577 from NIH for “Aged T-cell-derived cytokines impact meningeal lymphatics and contribute to AD”
$827,228 from NIH for “Neuroimmunology of AD and CAA with focus on innate immunity and lymphatics” - Abraham Qavi, MD, PhD
$761,686, 4-year, Mentored Clinical Scientist Research Career Development Award (K08 award) from NIH for “Development of Optofluidic Resonators for Filoviral Detection” - Katherine Schwetye, MD, PhD
$410,984 from NIH for “Human in vivo stable isotope labeling kinetics (iSILK) to quantify brain amyloid plaque kinetics”
September
- Eric Duncavage, MD
$261,450 from NIH for “Whole Genome Sequencing for Genomic Evaluation and Risk Stratification of Patients with Myelodysplastic Syndromes” - Steve Persaud, MD, PhD
One-year, $204,944 research supplement to Dr. John DiPersio’s R35 grant for the project entitled “Optimizing Hematopoietic Stem Cell Transplantation for the Treatment of Hematological Malignancies”
December
- Marco Colonna, MD
$499,998 from NIH for “Impact of Meningeal B Cells in Central Nervous System Autoimmunity” - Takeshi Egawa, MD, PhD
$300,000 from NIH for “CD8 T cell fate decision instructed by IL-2”
July
- Ali Ellebedy, PhD
$110,000 from Bill & Melinda Gates Foundation for “Early Events and Role of FcR Pathways in Immunity to mRNA Vaccines” - Steven L. Teitelbaum, MD
$10,000 from The Foundation For Barnes-Jewish Hospital for “Avioli Lecture Award”
August
- Gautam Dantas, PhD
$748,687 from CDC for “Interrogating the Phylogenomics and Mobilome of Colonizing Multidrug Resistant Organisms (MDROs) in Hospitalized Patients and Community-Dwellers in Pakistan”
September
- Daved Fremont, PhD
$1.39M from NIH for “B Cell Epitope Discovery and Mechanisms of Antibody Protection” - Jonathan Kipnis, PhD
$249,999 from Carol and Gene Ludwig Family Foundation for “Exhibit B-3 Meningeal lymphatic vessels in Alzheimer’s disease” - Nima Mosammaparast, MD, PhD
$45,000 from NIH for “Structural Cell Biology of DNA Repair Machines”
October
- Kathleen Sheehan, PhD
$300,000 from NGM Biopharmaceuticals for “Elucidating the Role of LAIR1 in Controlling Tumor Immunity”
November
- Gautam Dantas, PhD
$123,589 from bioMerieux for “Validation of bioMerieux EPISEQ CS and EPISEQ 16S using Wash U whole bacterial genomes and metagenomics 16S rRNA gene sequence databases” - Takeshi Egawa, MD, PhD
$78,750 from NIH for “Developing tools to study relationship between oxidative stress in T cell dysfunction” - Jeffrey Gordon, MD
$824,113 from Bill & Melinda Gates Foundation for “Maternal Microbiome directed therapeutic foods development”
December
- Ali Ellebedy, PhD
$735,765 from Moderna Therapeutics for “Defining the Cross-Reactivity and Durability of Human B Cell Responses to SARS-CoV-2 Variants-Based mRNA Vaccination”
$1.13M from Moderna Therapeutics for “Defining the Diversity and Specificity of Human B Cell Response to Influenza Virus mRNA-Based Vaccines” - Scott Handley, PhD
$52,838 from The Leona M. and Harry B. Helmsley Charitable Trust for “Anti-phage Antibodies in Stratifying Crohn’s Disease Diagnosis and Treatment Response” - Jonathan Kipnis, PhD
$172,500 from Cure Alzheimer’s Fund for “Contribution of skull bone marrow-derived cells to Alzheimer’s disease”
$300,000 from anonymous foundation for “Contribution of skull bone marrow-derived cells to Alzheimer’s disease”