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At the forefront of precision medicine, the CAP/CLIA Clinical Genomics Laboratory brings together decades of expertise through the integration of the Cytogenetics & Molecular Pathology Laboratory and Genomics and Pathology Services (GPS).

Overview

The Clinical Genomics Core provides a comprehensive menu of cytogenetic tests for human and mouse tissues (for example mouse embryonic stem cells, cancer cell lines, skin, peripheral blood, buccal cells, bone marrow etc).

The core also provides consultancy on designing projects involving karyotyping, custom FISH probe design, FFPE FISH, analyses of data from chromosomal microarrays. We also help in performing high resolution genomic scans that provide insight into regions of the genome that are pathogenic in various neoplasms, leading to an understanding of the molecular pathways that play a role in the biology of cancer. We also help with genomics assays, and can help with analysis of research NGS as well.

We are currently engaged in the chromosome analysis of various primate species, allowing us to extend our research beyond human and mouse studies. While we have previously worked with chimpanzee cell lines, this information is not listed on our website. For inquiries regarding other species, please consult the director.

We offer consultation and support for clinical trials/studies for which CAP/CLIA certification is needed.

Services are available for human and mouse tissues. For inquiries regarding other species, please consult the director.

  • Chromosome analysis (karyotyping)
  • Tissue culture
  • FISH analysis
  • Chromosomal Microarray Analysis

Phone: 314-747-2086 | Fax: 314-747-5642
Email: ampcorelab@path.wustl.edu

Location: Cortex Building, Room 209

Additional Contacts

Laboratory Director:

Julie A. Neidich, MD

Professor, Pathology & Immunology

Labs

Clinical Genomics Laboratory – Cytogenetics, Clinical Genomics Laboratory – Sequencing

Divisions

Genomic and Molecular Pathology

Division: Genomic & Molecular Pathology

Clinical Laboratory Manager:

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Clinical Laboratory Manager

Kevin Bowling, PhD

Associate Professor, Pathology & Immunology

Divisions

Genomic and Molecular Pathology

Division: Genomic & Molecular Pathology

Microscope

Equipment

If you have a question, chances are you’ll find the answer here. Your understanding matters to us, and we’re here to help simplify your journey.

10 Olympus BX51, 5 Ziess light microscopes, 3 Olympus and 1 Ziess fluorescent microscopes (FISH), 3 Nikon inverted microscopes and 2 Nikon dissection microscopes

17 Cytovision imaging workstations, 4 of which are FISH and 1 is an automated GSL-120 scanner

Hanabi 2 automated harvester

1 Bio Rad PCR machine

Miltenyi cell separater

3 Thermobrite FISH hybridization units

1 dual chamber and 1 single chamber Thermo CO2 incubator, 1 single chamber Fisher CO2 incubator and 2 dual chamber NuAire CO2 incubators

Slide drying chamber in a high humidity cytogenetics slide making room

Genomic & Molecular Pathology

The Division of Genomic and Molecular Pathology is committed to developing genetic tests that detect specific therapeutic targets in cancer. This is a crucial step in the application of precision medicine for individual patients, and is a significant contribution to the long and celebrated history in molecular and genomic discovery and analysis at the School of Medicine.

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