$60,000 in grants awarded to faculty in Pathology & Immunology Grants Rafa Sanguinetti Czepielewski, PhD, Postdoc Research Associate in the Randolph Lab, received a one-year $60,000 grant from the Lawrence C. Pakula, MD IBD Education, and Innovation Fund, entitled “Role of Mesenteric Tertiary Lymphoid Organs in Inflammatory Bowel Disease Progression and Anti-TNF Resistance”. Noteworthy Jack […]
Author: Alexis
Gordon Lab Featured in Science Magazine (Links to an external site)
Work from the lab of Jeffery Gordon, MD was recently featured in Science as a runner up for Breakthrough of The Year. This title is awarded yearly by the journal Science to recognize significant discoveries or developments in scientific research. The journal highlighted work by Arjun Raman, MD, PhD (PGY3 Clinical Pathology Resident) and others […]
Our Trainees Have the Opportunity to Attend a Multitude of Conferences
In the Department of Pathology and Immunology, we strongly support our trainees and any opportunities that come along to further their knowledge and experiences. Recently some of our trainees had the opportunity to attend the AABB and AMP conferences.
Grants & Notables Update: September-October 2019
Over $3 million in grants awarded to faculty in Pathology & Immunology. GRANTS Cole John Ferguson, MD, Instructor in Pathology and Immunology, received a five-year $164,015 grant from The National Institutes of Health, entitled “Ubiquitin Signaling in Epigenetic Regulation of Neuronal Development”. Chang Liu, MD, PhD, Assistant Professor of Pathology and Immunology, received a two-year […]
Kipnis named BJC Investigator (Links to an external site)
Jonathan Kipnis, PhD, an internationally recognized scientific leader in how the nervous and immune systems interact in neurodegenerative, neuroinflammatory and neurodevelopmental disorders, has been named a BJC Investigator at Washington University School of Medicine in St. Louis. He will join the Department of Pathology and Immunology, with secondary appointments in the neurology, neuroscience and neurosurgery departments.
Clues to improve cancer immunotherapy revealed (Links to an external site)
Cancer immunotherapy drugs trigger the body’s immune system to attack tumors and have revolutionized the treatment of certain cancers, such as lymphoma, lung cancer and melanoma. Yet, while some patients respond well to the drugs, others don’t respond at all. Cancer immunologists want to change that.
Flu antibody protects against numerous and wide-ranging strains (Links to an external site)
Researchers have found an antibody that protects mice against a wide range of lethal influenza viruses, according to a study from Washington University School of Medicine in St. Louis, Icahn School of Medicine at Mount Sinai in New York City, and Scripps Research in La Jolla, Calif. The antibody could serve as a template to […]
Trainees & Faculty Attend American Society of Dermatopathology
A number of Pathology & Immunology trainees and a faculty member had the amazing opportunity to present research at this year’s annual meeting of the American Society of Dermatopathology. The meeting was held October 17-20 in San Diego, CA. The experience, according to one trainee, was very educational, with lots of feedback on their work […]
Human gut microbes could make processed foods healthier (Links to an external site)
A specific microbe can break down a chemical common in manufactured foods
Annual CAP19 Meeting Informative for Trainees & Faculty
The College of American Pathologists Annual Meeting (CAP19) recently took place in Orlando, Florida and a number of faculty and trainees from the Pathology & Immunology department were in attendance.
Brestoff, Theunissen recognized by NIH for innovative research (Links to an external site)
Obesity expert Jonathan R. Brestoff, MD, PhD, and regenerative medicine specialist Thorold Theunissen, PhD, both of Washington University School of Medicine in St. Louis, have received High-Risk, High-Reward Research awards from the National Institutes of Health (NIH).
Ronald Jackups Jr., MD, PhD is a recipient of the 2019 AABB President’s Award
Ronald Jackups, MD, PhD, will receive the AABB President’s Award at the 2019 AABB Annual Meeting on October 19.
For gut microbes, not all types of fiber are created equal (Links to an external site)
Certain human gut microbes with links to health thrive when fed specific types of ingredients in dietary fibers, according to a new study from Washington University School of Medicine in St. Louis.
Jonathan Heusel, MD, PhD Presenting at Inauguration Symposium (Links to an external site)
Jonathan Heusel, MD, PhD will be one of several panelists discussing various topics at the upcoming inauguration of Andrew D. Martin on October 3, 2019.
Faculty and trainees recognized at 71st AACC Annual Scientific Meeting & Clinical Lab Expo
At the beginning of August, members from the Department of Pathology & Immunology attended the 71st AACC Annual Scientific Meeting & Clinical Lab Expo in Anaheim, CA.
Grants & Notables Update: May-June 2019
Over $800,000 in grants awarded to faculty in Pathology & Immunology.
For malnourished children, new therapeutic food boosts gut microbes, healthy development (Links to an external site)
A new type of therapeutic food, specifically designed to repair the gut microbiomes of malnourished children, is superior to standard therapy in an initial clinical trial conducted in Bangladesh.
Residents Receive Awards at Academy of Clinical Laboratory Physicians and Scientists Meeting
Eight trainees were awarded the Paul E. Strandjord Young Investigator Award, including Adam Bailey and Jonathan Brestoff who were recognized for their outstanding presentations.
Awardees Announced for Trainee Research Day 2019
The Department of Pathology & Immunology hosted its annual Trainee Research Day which celebrates research by residents and clinical fellows. It featured presentations both oral and poster from trainees.
Grants & Notables Update: March and April 2019
Over $8 million in grants were awarded to faculty in Pathology & Immunology.
Flaw in many home pregnancy tests can return false negative results (Links to an external site)
Each year, women in the U.S. rely on some 20 million home pregnancy tests to learn potentially life-altering news.
Colonna, Ley elected to National Academy of Sciences
Two physician-scientists at Washington University School of Medicine in St. Louis are among the 100 new members and 25 foreign associates elected to the National Academy of Sciences this year.
Grants & Notables Update: January and February 2019
Almost $7 million in grants awarded to faculty in Pathology & Immunology Paul Allen, PhD, Robert L. Kroc Professor of Pathology and Immunology and Interim Division Chief, Immunobiology, received five-year $2,349,441grant from The National Institutes of Health / National Institute of Allergy and Infectious Diseases, entitled “Strength of TCR:self-pMHC Interactions in the Periphery Instructs CD4+ […]
Probiotic bacteria evolve inside mice’s GI tracts
Probiotics – which are living bacteria taken to promote digestive health – can evolve once inside the body and have the potential to become less effective and sometimes even harmful, according to a new study from Washington University School of Medicine in St. Louis.
Trailblazer Award Brings Washington Univeristy Faculty Together
Eynav Klechevsky, assistant professor of pathology and immunology and Amit Pathak assistant professor of mechanical engineering & material science in the McKelvey School of Engineering at Washington University were awarded a three-year, $610,000 Trailblazer Award, from the National Institutes of Health’s National Institute of Biomedical Imaging and Bioengineering. This award provides funding to continue their […]
Grants & Notables Update: November and December 2018
Over $4.5 million in grants awarded to faculty in Pathology & Immunology Paul Allen, PhD, Robert L. Croc Professor of Pathology and Immunology and Interim Division Chief, Immunology, received a two-year $502,139 grant from National Institutes of Health / National Institute of Allergy and Infectious Diseases, entitled “Immune Regulation by Bacteroides Polysaccharide Capsules”. Ali Ellebedy, […]
Drug target identified for chemotherapy-resistant ovarian, breast cancer
Study finds mimic for BRCA genes that could be targeted to improve treatment.
Grant Updates and Notables – September & October 2018
Close to $9 million in grants awarded to faculty in Pathology & Immunology Gautam Dantas, PhD, Professor of Pathology and Immunology, of Biomedical Engineering, and of Molecular Microbiology, received a one-year $486,849 contract from Centers for Disease Control and Prevention (CDC) entitled “Impact of Early Life Antibiotic Treatment in Preterm Infants on Subsequent MDRO Colonization […]
$3.5 Million Grant Awarded to Dr. Gautam Dantas and Dr. Thaddeus Stappenbeck
The National Center for Complementary and Integrative Health of the National Institutes of Health (NIH) has awarded a $3.5 million grant to study how live bacteria can be used for drug delivery to Gautam Dantas, professor of pathology and immunology, and Thaddeus Stappenbeck, the Conan Professor of Laboratory and Genomic Medicine, both at the School of Medicine, and Tae Seok Moon, associate […]
Cordell Institute signs ‘Paris Call for Trust and Security in Cyberspace’
Washington University in St. Louis’ newly launched Cordell Institute for Policy in Medicine & Law has signed on as one of the early signatories of French President Emmanuel Macron’s “Paris Call for Trust and Security in Cyberspace,” announced Nov. 12 as part of the peace forum commemorating 100 years since the ending of World War I.
Link between autoimmune, heart disease explained in mice
People with autoimmune diseases such as psoriasis, lupus and rheumatoid arthritis are at high risk of developing cardiovascular disease, even though none of these conditions seem to target the cardiovascular system directly. Now, researchers at Washington University School of Medicine in St. Louis believe they have begun to understand the link between the two.
Grant Updates: July and August
Over $7 million in grants awarded to faculty in Pathology & Immunology Gautam Dantas, PhD, Professor of Pathology and Immunology, of Biomedical Engineering, and of Molecular Microbiology, received a five-year $3,484,069 grant from the National Institutes of Health, entitled “Tunable Therapeutic Modulation of the Gut Microbiome by Engineered Probiotics”. Paul Li-Hao Huang, PhD, Instructor in […]
Viruses in blood lead to digestive problems
While studying viruses best known for infecting the brain, researchers at Washington University School of Medicine in St. Louis stumbled upon clues to a conundrum involving a completely different part of the anatomy: the bowel, and why some people possibly develop digestive problems seemingly out of the blue.
Genetic testing helps predict disease recurrence in myelodysplastic syndrome
A DNA-based analysis of blood cells soon after a stem cell transplant can predict likelihood of disease recurrence in patients with myelodysplastic syndrome (MDS), a group of cancerous disorders characterized by dysfunctional blood cells, according to new research at Washington University School of Medicine in St. Louis. Such a practice could help doctors identify patients […]
Gordon receives Luminary Award
Jeffrey I. Gordon, MD, of Washington University School of Medicine in St. Louis, has received a 2018 Luminary Award from the Precision Medicine World Conference. He is being honored for his pioneering work in founding the field of gut microbiome research and for fundamentally altering the understanding of the origins of human health and disease, especially as […]
Grant Updates: May and June
Over $500,000 in grants awarded to faculty in Pathology & Immunology Takeshi Egawa, M.D., Ph.D., Associate Professor of Pathology and Immunology, received a two-year $155,875 grant from the National Institutes of Health, entitled “The Role of TH1 CD4 T Cells in Control of Viral Infection. Ali Ellebedy, Ph.D., Assistant Professor, Pathology & Immunology, received a […]
Burnham & Dantas Receive Distinguished Faculty Awards
Each year, Washington University School of Medicine faculty members have the opportunity to nominate their peers for Distinguished Faculty Awards.
Laboratory Outreach at Barnes Jewish Hospital and Beyond
The faculty in the Division of Laboratory and Genomic Medicine (LGM) serve as medical directors for the clinical laboratories at Barnes Jewish Hospital (BJH); however, they also provide medical direction and clinical consulting services to hospital laboratories in the St. Louis region and beyond.
Virology Testing at Barnes Jewish Hospital
Virology testing previously performed at the St. Louis Children’s Hospital (SLCH) Virology Laboratory officially transitioned to the Barnes Jewish Hospital (BJH) Molecular Infectious Disease Laboratory (MIDL) on January 29, 2018.
New Heparin-Induced Thromboctyopenia (HIT) Screening Test Method
Beginning May 1st, the Core Lab will transition from the current ELISA anti-PF4/heparin antibody test to a latex immunoturbidimetric assay (LIA) performed on the TOPS coagulation analyzer. The test will be available 24/7 with an in-lab turnaround time of 1-2 hours. Laboratory comparisons to SRA send out results show a sensitivity of 100% and a […]
Microbiology Update: Availability of Antimicrobial Susceptibility Testing for New Antimicrobial Agents
Infections due to antibiotic resistant bacteria are a global public health crisis. To help combat infections with multi-drug resistant bacteria, there has been a recent surge in the development of antimicrobial agents. The Barnes Jewish Hospital Microbiology Laboratory is now able to perform susceptibility testing for a number of these new antibiotics. Information regarding this […]
Featured Colleague: Stephen Roper, PhD
Stephen Roper joined Washington University as Assistant Professor of Pathology and Immunology and Assistant Director, Pediatric Laboratory Services in the Division of Laboratory and Genomic Medicine in August, 2017. He is NRCC (National Registry Certified Chemists) certified in Clinical Chemistry. Dr. Roper obtained his BS and MS at Texas Tech University and his PhD at […]
Gordon receives British Royal Society’s highest honor
Jeffrey I. Gordon, MD, of Washington University School of Medicine in St. Louis, has received the 2018 Copley Medal from the Royal Society in Britain. He is being honored for his studies of human gut microbial communities, which have led to a fundamental shift in the way scientists understand the relationship between microbes, health and […]
Grant Updates: March & April 2018
Nearly $3.9 million in grants awarded to faculty in Immunobiology and Laboratory & Genomic Medicine Carey-Ann Burnham, Ph.D., Associate Professor of Pathology and Immunology, of Pediatrics, and of Molecular Microbiology, and Medical Director, Clinical Microbiology Laboratory, received a five-month $10,568 grant from the National Institutes of Health, entitled “A Cloud-Based WGS Platform for Routine Surveillance […]
Cellular Therapy Laboratory Transplant Milestone
As highlighted in BJC Today in December 2017, the Bone Marrow and Stem Cell Transplant Program met a milestone of 7,500 transplants!
Testing For Insulin, C-Peptide and DHEAS To Be Performed at Barnes Jewish Hospital
Effective May 1st, Insulin and C-peptide and Dehydroepiandrosterone sulfate (DHEAS) (effective May 1st) will no longer be sent to Mayo Laboratories.
Bacteria’s appetite may be key to cleaning up antibiotic contamination
Gautam Dantas, PhD is senior author on a study showing antibiotics in the environment contribute to drug resistance.
Psoriasis treated with compound derived from immune cells
A study lead by Maxim Artyomov, PhD shows that a compound derived from the body’s own immune cells can treat psoriasis in mice and holds promise for other autoimmune diseases.
How highly contagious norovirus infection gets its start
Virus infects rare intestinal cells in mice; findings point to therapeutic strategy
Antibiotic use increases risk of severe viral disease in mice
Senior author Michael Diamond, MD, PhD reports that killing gut bacteria with drugs weakens the immune response