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Three researchers at Washington University School of Medicine in St. Louis including Steffen Storck, PhD, a postdoctoral researcher in the Department of Pathology & Immunology, recently received funding from the Alzheimer’s Association for projects that aim to study and make progress against the disease.
New research from scientists at Washington University School of Medicine in St. Louis suggests that updated booster shots will be important for shoring up population immunity as new variants emerge – but there’s a caveat. Their research, published April 3 in Nature, shows that vaccinating people against the original strain of the virus and then […]
The Department of Pathology & Immunology at Washington University School of Medicine shined at the USCAP Annual Meeting in 2023. Notably, Dr. Sanica Bhele and Dr. Hansini Laharwani, were honored with awards at the meeting, which was held March 11 – 16 in New Orleans, LA. Several faculty and trainees presented posters at the event, […]
Researchers at Washington University School of Medicine in St. Louis including Ali Ellebedy, PhD, an associate professor of pathology & immunology, of medicine and of molecular microbiology; and Daved Fremont, PhD, a professor of pathology & immunology, of biochemistry & molecular biophysics and of molecular microbiology, are working to reduce the risk of another devastating […]
The Colonna Lab recently had a paper published in Cell Reports, “Transcriptomic atlas and interaction networks of brain cells in mouse CNS demyelination and remyelination.” The paper by co-first authors JinChao Hou, PhD, and Yingyue Zhou, PhD, postdoctoral researchers in the Colonna Lab, presents a high-resolution single-nucleus RNA sequencing (snRNA-seq) analysis of gene expression changes […]
Liang-I Kang, MD, PhD, Instructor of Anatomic and Molecular Pathology in the Department of Pathology & Immunology at Washington University School of Medicine, has received a K12 Paul Calabresi Career Development Award in Clinical Oncology from NIH’s National Cancer Institute (NCI). The award is meant to “increase the number of clinicians (MDs, DOs, PharmDs, nurses […]
Erika Crouch, MD, PhD, Professor of Pathology & Immunology and Vice Chair of the Office of Education at Washington University School of Medicine, has received the Diversity Distinguished Service Teaching Award. The award, which honors Dr. Crouch’s teaching in the 2021-2022 academic year, is from the Washington University School of Medicine entering class of 2021. […]
Nearly two dozen experimental therapies targeting the immune system are in clinical trials for Alzheimer’s disease, a reflection of the growing recognition that immune processes play a key role in driving the brain damage that leads to confusion, memory loss and other debilitating symptoms. Many of the immunity-focused Alzheimer’s drugs under development are aimed at […]
Vincent Peng, an MD/PhD student in the Colonna Lab in the Department of Pathology & Immunology at Washington University School of Medicine, and Renee Wu, an MD/PhD student in the Murphy Lab in the Department of Pathology & Immunology at Washington University School of Medicine, were recently selected as Olin Fellows. Olin Fellowships are presented […]
Jeffrey I. Gordon, MD, explores the “vast, mysterious world” of the gut microbiome to develop innovative therapies for treating childhood malnutrition and restoring kids’ healthy growth. In recognition of his groundbreaking research, Gordon, who is the director of the Center for Genome Sciences and Systems Biology at Washington University School of Medicine in St. Louis, […]
ChromoSeq, an advanced diagnostic assay developed in the Department of Pathology & Immunology at Washington University School of Medicine in St. Louis, was recently approved for reimbursement by The Centers for Medicare & Medicaid Services (CMS), a milestone for test developers and a win for patients with myeloid malignancies. The test is based on whole […]
Sonika Dahiya, MD, Professor of Pathology & Immunology and Head of Neuro-Oncology in the Department of Pathology & Immunology at Washington University School of Medicine, was recently named to the Working Committee of the Consortium to Inform Molecular and Practical Approaches to CNS Tumor Taxonomy (cIMPACT-NOW). This prestigious consortium was established under the sponsorship of […]
Nicholas Borcherding, MD, PhD, resident in Clinical Pathology and a member of the Physician Science Training Program (PSTP) in the Department of Pathology & Immunology at Washington University School of Medicine, recently received a 2023 Emerging Generation Award from The American Society for Clinical Investigation (ASCI). The award recognizes post-MD, pre-faculty appointment physician-scientists who are […]
Immunotherapy has transformed cancer care. In advanced melanoma, for example, the most fatal form of skin cancer, the five-year survival rate has risen from less than 10% to more than 50% since immunotherapy was introduced in 2011. Still, only about half of melanoma patients respond to immunotherapy, and those who do not respond face a […]
The Department of Pathology & Immunology at Washington University School of Medicine is pleased to announce ten physicians have been named Castle Connolly Top Doctors in 2023. “The recognition of these physicians is a testament to the high quality of our entire faculty, whose work benefits patients across our entire region,” said Richard J. Cote, […]
Stephen Persaud, MD, PhD, Instructor of Pathology & Immunology in the Department of Pathology & Immunology at Washington University School of Medicine, was recently named an American Society of Hematology (ASH) Scholar for 2023. One of ASH’s most prestigious research award programs, the ASH Scholar Awards support early career investigators dedicated to careers in hematology […]
Kenneth Murphy, MD, PhD, Eugene Opie First Centennial Professor in the Department Pathology & Immunology at Washington University School of Medicine, was named a Distinguished Fellow by the American Association of Immunologists (AAI). The program annually recognizes members of AAI “for distinguished careers and outstanding scientific contributions as well as their service to AAI and […]
Jeffrey I. Gordon, MD, the Dr. Robert J. Glaser Distinguished University Professor and director of the Edison Family Center for Genome Sciences & Systems Biology at Washington University School of Medicine in St. Louis, has been named this year’s recipient of the Dr. Paul Janssen Award for Biomedical Research. The honor recognizes Gordon’s groundbreaking studies of the […]
S. Joshua Swamidass, MD, PhD, Associate Professor of Pathology & Immunologyat Washington University School of Medicine and Associate Professor of Biomedical Engineering at Washington University in St. Louis, was recently elected a Fellow of the American Association for the Advancement of Science (AAAS). Dr. Swamidass is recognized by AAAS “for distinguished contributions to the field […]
Richard J. Cote, MD, FRCPath, FCAP, Professor and Chair, Department of Pathology & Immunology at Washington University School of Medicine and Pathologist-in-Chief at Barnes-Jewish Hospital, was named a Castle Connolly Top Doctor in 2023. Every year, Castle Connolly accepts peer-only nominations for physicians at leading health centers including Washington University School of Medicine. The Castle […]
A growing pile of evidence indicates that the tens of trillions of microbes that normally live in our intestines — the so-called gut microbiome — have far-reaching effects on how our bodies function. Members of this microbial community produce vitamins, help us digest food, prevent the overgrowth of harmful bacteria and regulate the immune system, […]
Emil Raphael Unanue, MD, an internationally renowned immunologist at Washington University School of Medicine in St. Louis, died Dec. 16, 2022, surrounded by family in St. Louis after a two-year battle with glioblastoma. He was 88. Head of the Department of Pathology & Immunology at the School of Medicine from 1985 to 2006, Unanue built […]
The cancer therapy known as CAR-T has revolutionized treatment of some blood cancers since it was introduced in 2017. The therapy uses genetically altered immune cells to home in on cancer cells and destroy them. Now, studying mice with an autoimmune disease similar to multiple sclerosis (MS), researchers at Washington University School of Medicine in […]
Alzheimer’s, Parkinson’s and many other neurodegenerative diseases are marked by damaging clusters of proteins in the brain. Scientists have expended enormous effort searching for ways to treat such conditions by clearing these toxic clusters but have had limited success. Now, researchers at Washington University School of Medicine in St. Louis have found an innovative way […]
Gary Grajales-Reyes, MD, PhD, an assistant professor of pathology & immunology at Washington University School of Medicine in St. Louis, has received an Early Independence Award from the National Institutes of Health (NIH). The award supports outstanding junior scientists with the intellect, scientific creativity, drive, and maturity to bypass or shorten the traditional postdoctoral training […]
Four faculty members at Washington University School of Medicine in St. Louis have been elected to the National Academy of Medicine, a part of the National Academy of Sciences. They are Opeolu M. Adeoye, MD; Farshid Guilak, PhD; David H. Gutmann, MD, PhD; and Jonathan Kipnis, PhD. Membership in the academy is considered one of the […]
Robert D. Schreiber, the Andrew M. and Jane M. Bursky Distinguished Professor at Washington University School of Medicine in St. Louis, has received the 2023 Richard V. Smalley Memorial Award from the Society for Immunotherapy of Cancer. He joins three other scientists recognized by the society this year for outstanding contributions to the field of […]
An innovative project from the Department of Pathology & Immunology at Washington University School of Medicine and Barnes Jewish Hospital (BJH) won a 2022 QUEST (Quality, Excellence and Safety Team) Award, an accolade that recognizes contributions made to improve organization performance and quality of care through the use of process and outcome measures. The WashU […]
Suzanne R. Thibodeaux, MD, PhD, Associate Professor of Pathology & Immunology at Washington University School of Medicine, was selected as Associate Scientific Member of the BEST Collaborative. The BEST (Biomedical Excellence for Safer Transfusion) Collaborative is an international collaborative of blood providers, industry and academic experts who undertake studies, publish guidance and recommend procedures, to improve the […]
Jeffrey I. Gordon, MD, the Dr. Robert J. Glaser Distinguished University Professor and director of the Edison Family Center for Genome Sciences & Systems Biology at Washington University School of Medicine in St. Louis, will be the inaugural recipient of the David and Beatrix Hamburg Award for Advances in Biomedical Research and Clinical Medicine, a […]
The Corbo Lab recently had a paper published in Current Biology, “A mechanism for red coloration in vertebrates.” In the paper, researchers define the enzymatic mechanism through which vertebrates make red color by studying the photoreceptors of chickens. This mechanism plays a fundamental role in animal coloration and color vision, said Joe Corbo, MD, PhD, […]
The Brestoff Lab had a paper published in Cell Metabolism. The paper, “Dietary lipids inhibit mitochondria transfer to macrophages to divert adipocyte-derived mitochondria into the blood,” summarizes three key findings: Adipocytes transfer their mitochondria to tissue-specific networks of cells in white, beige and brown fat, with macrophages being the dominant recipient cells in each tissue. […]
We are thrilled to announce our residency program has been named among the best in the nation. According to a new ranking published by professional medical network Doximity, the Pathology & Immunology Residency Program at Washington University School of Medicine ranks number one in size, number six in research output, and number eleven in overall […]
Three faculty members in the Department of Pathology & Immunology at Washington University School of Medicine were recently awarded a multi-year, multi-million dollar grant to research the aging brain. The group, which comprises Jonathan Kipnis, PhD, BJC Investigator, Alan A. and Edith L. Wolff Distinguished Professor of Pathology and Immunology; Gwen Randolph, PhD, Emil R. […]
About 18 million children under age 5 suffer from severe acute malnutrition, and over 3 million children die from it each year. Treatment with high-calorie supplemental foods and antibiotics can prevent deaths, but these interventions often have limited impact on the long-term effects of severe acute malnutrition, such as persistent stunted growth, disrupted immune function […]
Jeffrey I. Gordon, MD, of Washington University School of Medicine in St. Louis, has been named the 2022 Senior Scientist Winner of the Innovators in Science Award administered by the New York Academy of Sciences and sponsored by Takeda Pharmaceuticals.
Dr. Melanie Yarbrough is the recipient of the 2022 Ellis Benson Award, given by the Academy of Clinical Laboratory Physicians and Scientists (ACLPS) in recognition of her work in advancing diagnostic methods for infectious diseases such as bloodstream and urinary tract infections. The Ellis Benson Award is the premier award of ACLPS to a young faculty member in […]
The director of the Centers for Disease Control and Prevention, Rochelle P. Walensky, MD, will participate in a conversation about the pandemic Thursday, March 3, from 8 to 9 a.m. at Washington University School of Medicine in St. Louis. The virtual event, available via livestream, will be geared toward faculty, staff, students and trainees on the […]
Following departmental strategic planning, the Pathology & Immunology Office of Faculty Development (OFD) was founded in 2020. OFD supports our departmental core values (excellence, respect, inclusion, and diversity), and the mission of the OFD is to support a thriving and diverse department with professionally happy and healthy faculty who are productive, well recognized, and respected […]
For at least six months after COVID-19 vaccination, antibodies produced by immune cells become steadily more formidable and more precisely targeted against the virus that causes COVID-19, according to a study of the antibody response to the Pfizer-BioNTech vaccine by researchers at Washington University School of Medicine in St. Louis.
When South African scientists announced in November that they had identified a new variant of the virus that causes COVID-19, they also reported two worrying details: one, that this new variant’s genome was strikingly different from that of any previous variant, containing dozens of mutations compared with the original virus that emerged in 2019; and […]
The Association for the Advancement of Blood & Biotherapies recently honored Brenda J. Grossman, MD, and Jeffrey P. Henderson, MD, PhD, noted researchers at Washington University School of Medicine in St. Louis, with a 2021 President’s Award.
The American Society for Clinical Investigation recently announced their list of 2022 Young Scientist Awardees, and Jonathan Brestoff, MD, PhD is among those being recognized. The ASCI Council Young Physician-Scientist Awards recognize physician-scientists who are early in their first faculty appointment and have made notable achievements in their research. With these awards, the ASCI seeks to encourage and inspire […]
A new episode of the School of Medicine podcast, “Show Me the Science,” has been posted. This episode of ‘Show Me the Science’ features, Ali Ellebedy, PhD and looks at how vaccines and prior infections provide some immunity as omicron continues to spread.
The first two vaccines created with mRNA vaccine technology — the Pfizer/BioNTech and Moderna COVID-19 vaccines — are arguably two of the most effective COVID vaccines developed to date. In clinical trials, both were more than 90% effective at preventing symptomatic infection, easily surpassing the 50% threshold the Food and Drug Administration had set for […]
The Centers for Disease Control and Prevention (CDC) has awarded $22 million to nearly 30 organizations in 50 countries for efforts to combat antimicrobial resistance and other infection-related threats to health. Part of that funding will support 11 short-term research projects aimed at identifying new solutions to help prevent antimicrobial-resistant infections and their spread, including two such […]
Jonathan Kipnis, PhD, the Alan A. and Edith L. Wolff Distinguished Professor of Pathology & Immunology and a BJC Investigator at Washington University School of Medicine in St. Louis, has been named an academic editor of the Journal of Experimental Medicine, a high-impact journal that publishes papers on immunology, cancer biology, vascular biology, microbial pathogenesis, neuroscience and […]
People who received two doses of the Pfizer COVID-19 vaccine while on TNF inhibitors — a class of immunosuppressants used to treat rheumatoid arthritis and other autoimmune conditions — generated less powerful and shorter-lived antibodies against the virus that causes COVID-19 than healthy people and those on other kinds of immunosuppressants, according to a study […]
Ann M. Gronowski, PhD, has agreed to serve as the interim Clinical Co-Chief of the Division of Laboratory and Genomic Medicine (LGM) in the Department of Pathology and Immunology (P&I), and CLIA Medical Director of Barnes-Jewish Hospital Clinical Laboratories, starting January 1, 2022. Ann is currently Vice Chair of Faculty Affairs & Development and Medical […]
For hard-to-treat leukemias, lymphomas and other blood cancers, stem cell transplantation is the gold standard of care. The procedure involves replacing a patient’s own blood-forming stem cells with a donor’s stem cells and, in the process, eradicating cancer cells in the blood, lymph nodes and bone marrow.