#LC2025 at WashU Medicine
September 3-5, 2025

We are proud to announce that the 18th International Workshop on Langerhans Cells (LC2025) will take place from September 3-5, 2025, hosted on the campus of Washington University School of Medicine in St. Louis, Missouri.

Since its inception in 1984, this biannual workshop has established itself as the premier international convention in the field of Langerhans cell (LC) research and a sister meeting to the international Dendritic Cell (DC) conference. LC2025 continues this rich tradition, bringing together the world’s leading experts, the brightest young researchers, and key industry partners for three days of groundbreaking science and collaboration.

The scientific program will highlight the latest insights into the biology and translational relevance of LCs and related myeloid cells of the skin. Topics include: Ontogeny and differentiation, Tissue homeostasis and migration, Interaction with microbiota and pathogens, Neuroimmunology, Cancer and immunotherapy.

LC2025 is designed to foster robust dialogue across disciplines and career stages, during the sessions and social events ensuring ample opportunities for young investigators to share their work and connect with global leaders in the field.

Join us in St. Louis for an inspiring and interactive scientific gathering that advances the field of skin immunology and myeloid cell biology.

We look forward to welcoming you to LC2025!

Eynav Klechevsky
LC2025 Chair

Click here for past meetings


Submit an Abstract

Register Now
The abstract submission deadline has been extended to JULY 1st!

Registration

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Social Events

Event Info

Meet me in St. Louis

Local Attractions


Location

Eric P. Newman Education Center (EPNEC)
Washington University Medical Campus
Open map »


Speakers

Carl E. Allen
Baylor College of Medicine
Niro Anandasabapathy
Weill Cornell Medicine 
Clare Bennett
University College London
Bjorn Clausen
Johannes Gutenberg-University Mainz
Marco Colonna
WashU Medicine
Diana Dudziac
Universitätsklinikum Jena
Vincent Flacher
Vincent Flacher
Institute of Molecular and Cellular Biology
Yonatan Ganor
Institut Cochin 
Michel  Giliet
University of Lausanne
Florent Ginhoux
Gustave Roussy
Andrew Harman
University of Sydney
Avi-Hai Hovav
Hebrew University of Jerusalem
Juliana Idoyaga
UC San Diego
Kenji Kabashima
Kyoto University
Dan Kaplan
University of Pittsburgh
Jonathan Kipnis
WashU Medicine
Eynav Klechevsky
WashU Medicine
Kenneth Murphy

WashU Medicine
Gwendalyn Randolph
WashU Medicine
Kodi Ravichandran
WashU Medicine
Franca Ronchese
Malaghan Institute
Herbert Strobl
Medical University Graz
Roxane Tussiwand
NIH/NIDCR

Program

Day 1 – Wednesday, September 3

8:00–9:30 AM – Registration and Breakfast

9:45–10:00 AM – Opening Remarks
Eynav Klechevsky (Chair)

Session 1: Development and Subsets

Chair: TBD

10:00–10:30 AM – Ken Murphy
“DCs, poor little LC wannabes”

10:30–10:45 AM – Herbert Strobl
“New data on transcription factor dependency of normal skin LCs, and recently established a human CRISPR model for LCH, which we currently use for molecular studies”

10:45–11:15 AM – Selected Talk 1

11:15–11:30 AM – Clare L. Bennett
“Defining Langerhans cell identity”

11:30–12:00 PM – Selected Talk 2

12:00–12:30 PM – Florent Ginhoux
“Ontogeny of Dendritic Cells”

12:30–1:30 PM – Lunch Break and Poster Viewing

Session 2: Special Session

Moderated by: TBD

1:30–3:00 PM – Panel Discussion and/or Workshop

Panelists and additional abstract talks to be announced.

3:00–3:45 PM – Coffee Break and Poster Viewing

Session 3: Migration

Chair: TBD

3:45–4:15 PM – Gwen Randolph
“Cellular and molecular trafficking from the skin to lymph nodes and beyond”

4:15–4:45 PM – Juli Idoyaga (Title TBD)

4:45–5:00 PM – Selected Talk 3

5:00–5:30 PM – Björn Clausen
“Cellular anchors and microtubules: Regulation of Langerhans cells by E-cadherin and post-translational tubulin modifications”

7:00–8:30 PM – Welcome Dinner at the Missouri Botanical Garden

Day 2 – Thursday, September 4

8:00–9:00 AM – Registration and Breakfast

Session 4: Cutaneous Responses

Chair: TBD

9:00–9:30 AM – Marco Colonna
 “Immune tolerance: a role for Rorgt DC”

9:30–10:00 AM – Franca Ronchese
“Allergy induction by dermal dendritic cells”

10:00–10:30 AM – Vincent Flacher
“Epidermal maintenance of Langerhans cells relies on autophagy-regulated lipid metabolism”

10:30–11:00 AM – Kodi Ravichandran
“Dendritic cells, efferocytosis, and wound repair”

11:30–12:00 PM – Kenji Kabashima
“Immune–nonimmune cell interaction in the development of inducible skin-associated lymphoid tissue (iSALT)”

12:00–12:15 PM – Selected Talk 4

12:15–1:30 PM – Lunch Break and Poster Viewing

Session 5: Infections and Skin Responses to Pathogens

Chair: TBD

1:30–2:00 PM – Robert Modlin (Title TBD)

2:00–2:15 PM – Diana Dudziac (Title TBD)

2:15–2:45 PM – Andrew Harman
“Epithelial Langerhans cells vs dendritic cells in antigen presentation and viral transmission”

2:45–3:00 PM – Selected Talk 5

3:00–3:45 PM – Coffee Break and Poster Viewing

Session 6: Neuroimmunology

Chair: TBD

3:45–4:15 PM – Avi-Hai Hovav
“Regulation of Oral Intraepithelial Innervation by Langerhans Cells”

4:15-4:45 PM – Yonatan Ganor
“Neuroimmune interactions between LCs and nociceptors in health and disease”                                                                                                                           

4:45–5:15 PM – Dan Kaplan (Title TBD)

5:15–5:30 PM – Selected Talk 6

5:30–6:00 PM – Jonathan Kipnis (Title TBD)

7:15–11:00 PM – Maryland House Dinner & Party

Day 3 – Friday, September 5

8:30–9:30 AM – Registration and Breakfast

Session 7 – Myeloid cells in cutaneous tumor immunology and immunotherapy

Chair: TBD

9:30–10:00 AM – Michel Giliet (TBD)

10:00–10:30 AM – Carl Allen
“Langerhans Cell Histiocytosis: 2025 Update on Origins and Differentiation”

10:30–10:45 AM – Selected Talk 7

10:45–11:15 AM – Niroshana Anandasabapathy
“Architecting DC maturation towards tolerance and immunity.”

11:15–11:45 AM – Eynav Klechevsky (Title TBD)

11:45–12:00 PM – Closing Remarks

Afternoon Networking Activities

1:00–3:00 PM – Self-Guided Tour at the St. Louis Art Museum

3:30–6:30 PM – Informal Closing Gathering at the Four Seasons St. Louis with Light Hors d’Oeuvres

Social Events

Wednesday, September 3

Join us for dinner and drinks at the Spink Pavilion at the Missouri Botanical Garden overlooking the award-winning Garden grounds, Lily Ponds and Milles sculpture garden. This is a worldwide destination location and a crowned jewel of St Louis. Registration is required to attend. 

Thursday, September 4

Join us at The Maryland House with an open bar, a DJ, dancing and appetizers from 7:00 – 11:00pm. Registration is required to attend. 

Friday, September 5

Self-Guided Tours at the St. Louis Art Museum

*This event will take place on the last day and run from approximately 1:00pm – 3:00pm. The Saint Louis Art Museum collects, presents, interprets, and conserves works of art of the highest quality across time and cultures; educates, inspires discovery, and elevates the human spirit; preserves a legacy of artistic achievement for the people of St. Louis and the world; and engages, includes, and represents the full diversity of the St. Louis community supporting it. Registration is required to attend. 

Lodging

The Chase Park Plaza Royal Sonesta St. Louis (a 10 min walk from EPNEC Auditorium)
212 Kingshighway Blvd.
St. Louis, MO 63108 USA | map
Reserve now: LC2025 Group Rate/Chase

Click here to view directions from the airport.

DoubleTree by Hilton (just steps from EPNEC Auditorium)
4550 Forest Park Ave.
St. Louis, Missouri 63108 USA | map
Reserve now: LC2025 Group Rate/DoubleTree
*Complimentary Parking ($15/day value)
*Their 3rd floor connects to EPNEC
Auditorium

Click here to view directions from the airport.

St. Louis, MO

St. Louis, located along the Mississippi River in Missouri, offers a blend of historical charm and modern attractions. Notable landmarks include the iconic Gateway Arch, the lush Missouri Botanical Garden, and the stunning Cathedral Basilica of St. Louis. Visitors can explore the bustling Delmar Loop and historic Soulard district to enjoying the serene beauty of Forest Park (near WashU Medicine campus), which houses institutions like the St. Louis Art Museum, the Missouri History Museum, and the St. Louis Zoo. The city is also famous for its culinary delights, including St. Louis-style barbecue and toasted ravioli. With a blend of modern innovation and historical charm, St. Louis is a destination that promises engaging experiences for all.


Sponsors

Diamond

Gold

silver

patron


How to sponsor this event

We are asking you to join us in supporting this incredibly important workshop including both early-career and established researchers. Sponsors will be well publicized at the workshop by having their logo on our meeting website. In addition, exhibitor booths will be available to display your printed materials. Your support will directly contribute to the success of LC2025 and its mission to advance research and collaboration in this critical field.

Sponsorship tiers:

Patron Sponsor Level

  • Silver Logo placement in during-event slideshow
  • Silver Logo placement on in-person programs or signage
  • Name listed on email invitations and event webpage

Silver Sponsor Level

  • Silver Logo placement in during-event slideshow
  • Silver Logo placement on in-person programs or signage
  • Name listed on email invitations and event webpage
  • Opportunity to host a table at the event

Gold Sponsor Level

  • Gold Logo placement during-event slideshow
  • Gold Logo placement on in-person programs or signage
  • Name listed on email invitations and event webpage
  • Opportunity to host a table at the event

Diamond Sponsor Level

  • Distinguished-tier logo placement in during-event slideshow
  • Recognition before featured scientific speaker as a sponsor of that segment
  • Logo placement on in-person programs or signage
  • Name listed on email invitations and the event webpage
  • Opportunity to host a table at the event

Please contact our Events Manager Randi Lee for more information at lee.r@wustl.edu


Past Langerhans Cell Workshops

1984   Oslo, Norway
1988   Lyon, France
1991   Dallas, TX, USA
1995   Scheveningen, The Netherlands
1997   Fuschl / Salzburg, Austria
1999   New York, USA
2001   Stresa, Italy
2003   Tokyo, Japan
2005   Funchal, Madeira, Portugal
2007   Berne, Switzerland
2009   Funchal, Madeira, Portugal
2011   Innsbruck, Austria
2013   Amsterdam, The Netherlands
2015   Kyoto, Japan
2017   New York, USA
2019   Mainz, Germany
2023  Paris, France


Contact the Conference Coordinator

Randi Lee
Administrative Professional – Pathology and Immunology
314-273-1733
lee.r@wustl.edu