
18th International Workshop of Langerhans Cells
and Related Myeloid Cells of the Skin
#LC2025 at WashU Medicine
September 3-5, 2025
We are proud to announce that the 18th International Workshop on Langerhans Cells (LC2025) will take place from September 3-5, 2025, hosted on the campus of Washington University School of Medicine in St. Louis, Missouri.
Since its inception in 1984, this biannual workshop has established itself as the premier international convention in the field of Langerhans cell (LC) research and a sister meeting to the international Dendritic Cell (DC) conference. LC2025 continues this rich tradition, bringing together the world’s leading experts, the brightest young researchers, and key industry partners for three days of groundbreaking science and collaboration.
The scientific program will highlight the latest insights into the biology and translational relevance of LCs and related myeloid cells of the skin. Topics include: Ontogeny and differentiation, Tissue homeostasis and migration, Interaction with microbiota and pathogens, Neuroimmunology, Cancer and immunotherapy.
LC2025 is designed to foster robust dialogue across disciplines and career stages, during the sessions and social events ensuring ample opportunities for young investigators to share their work and connect with global leaders in the field.
Join us in St. Louis for an inspiring and interactive scientific gathering that advances the field of skin immunology and myeloid cell biology.
We look forward to welcoming you to LC2025!
Eynav Klechevsky
LC2025 Chair
Click here for past meetings
Submit an Abstract
Register Now
The abstract submission deadline has been extended to JULY 1st!
Registration
Program
Sponsors
Social Events
Meet me in St. Louis
Location
Eric P. Newman Education Center (EPNEC)
Washington University Medical Campus
Open map »

Speakers

Baylor College of Medicine

Weill Cornell Medicine

University College London

Johannes Gutenberg-University Mainz

WashU Medicine

Universitätsklinikum Jena

Institute of Molecular and Cellular Biology

Institut Cochin

University of Lausanne

Gustave Roussy

University of Sydney

Hebrew University of Jerusalem

UC San Diego

Kyoto University

University of Pittsburgh

WashU Medicine

WashU Medicine

UCLA

WashU Medicine

WashU Medicine

WashU Medicine

Malaghan Institute

Medical University Graz

NIH/NIDCR
Program
8:00–9:30 AM – Registration and Breakfast
9:45–10:00 AM – Opening Remarks
Eynav Klechevsky (Chair)
Session 1: Development and Subsets
Chair: TBD
10:00–10:30 AM – Ken Murphy
“DCs, poor little LC wannabes”
10:30–10:45 AM – Herbert Strobl
“New data on transcription factor dependency of normal skin LCs, and recently established a human CRISPR model for LCH, which we currently use for molecular studies”
10:45–11:15 AM – Selected Talk 1
11:15–11:30 AM – Clare L. Bennett
“Defining Langerhans cell identity”
11:30–12:00 PM – Selected Talk 2
12:00–12:30 PM – Florent Ginhoux
“Ontogeny of Dendritic Cells”
12:30–1:30 PM – Lunch Break and Poster Viewing
Session 2: Special Session
Moderated by: TBD
1:30–3:00 PM – Panel Discussion and/or Workshop
Panelists and additional abstract talks to be announced.
3:00–3:45 PM – Coffee Break and Poster Viewing
Session 3: Migration
Chair: TBD
3:45–4:15 PM – Gwen Randolph
“Cellular and molecular trafficking from the skin to lymph nodes and beyond”
4:15–4:45 PM – Juli Idoyaga (Title TBD)
4:45–5:00 PM – Selected Talk 3
5:00–5:30 PM – Björn Clausen
“Cellular anchors and microtubules: Regulation of Langerhans cells by E-cadherin and post-translational tubulin modifications”
7:00–8:30 PM – Welcome Dinner at the Missouri Botanical Garden
8:00–9:00 AM – Registration and Breakfast
Session 4: Cutaneous Responses
Chair: TBD
9:00–9:30 AM – Marco Colonna
“Immune tolerance: a role for Rorgt DC”
9:30–10:00 AM – Franca Ronchese
“Allergy induction by dermal dendritic cells”
10:00–10:30 AM – Vincent Flacher
“Epidermal maintenance of Langerhans cells relies on autophagy-regulated lipid metabolism”
10:30–11:00 AM – Kodi Ravichandran
“Dendritic cells, efferocytosis, and wound repair”
11:30–12:00 PM – Kenji Kabashima
“Immune–nonimmune cell interaction in the development of inducible skin-associated lymphoid tissue (iSALT)”
12:00–12:15 PM – Selected Talk 4
12:15–1:30 PM – Lunch Break and Poster Viewing
Session 5: Infections and Skin Responses to Pathogens
Chair: TBD
1:30–2:00 PM – Robert Modlin (Title TBD)
2:00–2:15 PM – Diana Dudziac (Title TBD)
2:15–2:45 PM – Andrew Harman
“Epithelial Langerhans cells vs dendritic cells in antigen presentation and viral transmission”
2:45–3:00 PM – Selected Talk 5
3:00–3:45 PM – Coffee Break and Poster Viewing
Session 6: Neuroimmunology
Chair: TBD
3:45–4:15 PM – Avi-Hai Hovav
“Regulation of Oral Intraepithelial Innervation by Langerhans Cells”
4:15-4:45 PM – Yonatan Ganor
“Neuroimmune interactions between LCs and nociceptors in health and disease”
4:45–5:15 PM – Dan Kaplan (Title TBD)
5:15–5:30 PM – Selected Talk 6
5:30–6:00 PM – Jonathan Kipnis (Title TBD)
7:15–11:00 PM – Maryland House Dinner & Party
8:30–9:30 AM – Registration and Breakfast
Session 7 – Myeloid cells in cutaneous tumor immunology and immunotherapy
Chair: TBD
9:30–10:00 AM – Michel Giliet (TBD)
10:00–10:30 AM – Carl Allen
“Langerhans Cell Histiocytosis: 2025 Update on Origins and Differentiation”
10:30–10:45 AM – Selected Talk 7
10:45–11:15 AM – Niroshana Anandasabapathy
“Architecting DC maturation towards tolerance and immunity.”
11:15–11:45 AM – Eynav Klechevsky (Title TBD)
11:45–12:00 PM – Closing Remarks
Afternoon Networking Activities
1:00–3:00 PM – Self-Guided Tour at the St. Louis Art Museum
3:30–6:30 PM – Informal Closing Gathering at the Four Seasons St. Louis with Light Hors d’Oeuvres
Social Events
Join us for dinner and drinks at the Spink Pavilion at the Missouri Botanical Garden overlooking the award-winning Garden grounds, Lily Ponds and Milles sculpture garden. This is a worldwide destination location and a crowned jewel of St Louis. Registration is required to attend.
Join us at The Maryland House with an open bar, a DJ, dancing and appetizers from 7:00 – 11:00pm. Registration is required to attend.
Self-Guided Tours at the St. Louis Art Museum
*This event will take place on the last day and run from approximately 1:00pm – 3:00pm. The Saint Louis Art Museum collects, presents, interprets, and conserves works of art of the highest quality across time and cultures; educates, inspires discovery, and elevates the human spirit; preserves a legacy of artistic achievement for the people of St. Louis and the world; and engages, includes, and represents the full diversity of the St. Louis community supporting it. Registration is required to attend.
Lodging
The Chase Park Plaza Royal Sonesta St. Louis (a 10 min walk from EPNEC Auditorium)
212 Kingshighway Blvd.
St. Louis, MO 63108 USA | map
Reserve now: LC2025 Group Rate/Chase
Click here to view directions from the airport.
DoubleTree by Hilton (just steps from EPNEC Auditorium)
4550 Forest Park Ave.
St. Louis, Missouri 63108 USA | map
Reserve now: LC2025 Group Rate/DoubleTree
*Complimentary Parking ($15/day value)
*Their 3rd floor connects to EPNEC
Auditorium
Click here to view directions from the airport.





St. Louis, MO
St. Louis, located along the Mississippi River in Missouri, offers a blend of historical charm and modern attractions. Notable landmarks include the iconic Gateway Arch, the lush Missouri Botanical Garden, and the stunning Cathedral Basilica of St. Louis. Visitors can explore the bustling Delmar Loop and historic Soulard district to enjoying the serene beauty of Forest Park (near WashU Medicine campus), which houses institutions like the St. Louis Art Museum, the Missouri History Museum, and the St. Louis Zoo. The city is also famous for its culinary delights, including St. Louis-style barbecue and toasted ravioli. With a blend of modern innovation and historical charm, St. Louis is a destination that promises engaging experiences for all.
Sponsors
Diamond
Gold
silver
patron

We are asking you to join us in supporting this incredibly important workshop including both early-career and established researchers. Sponsors will be well publicized at the workshop by having their logo on our meeting website. In addition, exhibitor booths will be available to display your printed materials. Your support will directly contribute to the success of LC2025 and its mission to advance research and collaboration in this critical field.
Sponsorship tiers:
Patron Sponsor Level
- Silver Logo placement in during-event slideshow
- Silver Logo placement on in-person programs or signage
- Name listed on email invitations and event webpage
Silver Sponsor Level
- Silver Logo placement in during-event slideshow
- Silver Logo placement on in-person programs or signage
- Name listed on email invitations and event webpage
- Opportunity to host a table at the event
Gold Sponsor Level
- Gold Logo placement during-event slideshow
- Gold Logo placement on in-person programs or signage
- Name listed on email invitations and event webpage
- Opportunity to host a table at the event
Diamond Sponsor Level
- Distinguished-tier logo placement in during-event slideshow
- Recognition before featured scientific speaker as a sponsor of that segment
- Logo placement on in-person programs or signage
- Name listed on email invitations and the event webpage
- Opportunity to host a table at the event
Please contact our Events Manager Randi Lee for more information at lee.r@wustl.edu
Past Langerhans Cell Workshops
1984 Oslo, Norway
1988 Lyon, France
1991 Dallas, TX, USA
1995 Scheveningen, The Netherlands
1997 Fuschl / Salzburg, Austria
1999 New York, USA
2001 Stresa, Italy
2003 Tokyo, Japan
2005 Funchal, Madeira, Portugal
2007 Berne, Switzerland
2009 Funchal, Madeira, Portugal
2011 Innsbruck, Austria
2013 Amsterdam, The Netherlands
2015 Kyoto, Japan
2017 New York, USA
2019 Mainz, Germany
2023 Paris, France
Contact the Conference Coordinator
Randi Lee
Administrative Professional – Pathology and Immunology
314-273-1733
lee.r@wustl.edu