
Yang Cao, PhD
Assistant Professor, Pathology & Immunology
Director, LGG Fellowship
- Phone: 314-273-3225
- Email: cao.yang@wustl.edu
Division
- Laboratory & Genomic Medicine
Additional Titles
- Associate Medical Director, Cytogenetics & Molecular Pathology Laboratory
- Program Director, ABMGG Fellowship in Laboratory Genetics and Genomics
Education
- PhD, Genetics: University of Wisconsin-Madison, Madison, WI
- Fellow, ABMGG Clinical Cytogenetics and Genomics: Mayo Clinic, Rochester, MN
- Fellow, ABMGG Clinical Molecular Genetics and Genomics: Mayo Clinic, Rochester, MN
Board Certifications
- ABMGG Clinical Cytogenetics and Genomics
- ABMGG Clinical Molecular Genetics and Genomics
Recognition
- Fellow, American College of Medical Genetics
Clinical Interests
Dr. Cao’s clinical interests include new assay development and implementation as well as convergence and integration of a variety of methodologies into the next generation of clinical laboratory genomics. Dr. Cao also dedicates her efforts to fellowship training, molecular and genetic education, as well as career and professional development.
Selected Publications
Cao Y, Chtarbanova S, Petersen A, Ganetzky B. Dnr1 mutations cause neurodegeneration in Drosophila by activating the innate immune response in the brain Proc Natl Acad Sci U S A. 2013;110(19):E1752-1760. PMID:23613578 |
Cao Y, Mitchell E, Gorski J, Hollinger C, Hoppman N. Two cases with de novo 3q26.31 microdeletion suggest a role for FNDC3B in human craniofacial development Am J Med Genet A. 2016;170(12):3276-3281. PMID:27541078 |
Cao Y, Aypar U. A novel Xq22.1 deletion in a male with multiple congenital abnormalities and respiratory failure Eur J Med Genet. 2016;59(5):274-277. PMID:26995686 |
Cao Y, Hoppman N, Kerr S, Sattler C, Borowski K, Wick M, Highsmith W, Aypar U. False Negative Cell-Free DNA Screening Result in a Newborn with Trisomy 13 Case Rep Genet. 2016;2016:7397405. PMID:26998368 |
Cao Y, AlHumaidi S, Faqeih E, Pitel B, Lundquist P, Aypar U. A novel deletion of SNURF/SNRPN exon 1 in a patient with Prader-Willi-like phenotype Eur J Med Genet. 2017;60(8):416-420. doi:10.1016/j.ejmg.2017.05.003 PMID:28554868 |
Kounatidis I, Chtarbanova S, Cao Y, Hayne M, Jayanth D, Ganetzky B, Ligoxygakis P. NF-κB Immunity in the Brain Determines Fly Lifespan in Healthy Aging and Age-Related Neurodegeneration Cell Rep. 2017;19(4):836–848. PMID:28445733 (International collaboration) |
McNulty S, Evenson M, Corliss M, Love-Gregory L, Schroeder M, Cao Y, Lee Y, Drolet B, Neidich J, Cottrell C, Heusel J. Diagnostic Utility of Next-Generation Sequencing for Disorders of Somatic Mosaicism: A Five-Year Cumulative Cohort Am J Hum Genet. 2019;105(4):734-746. doi:10.1016/j.ajhg.2019.09.002. PMID:31585106 |
Uguen K, Krysiak K, Audebert-Bellanger S, Redon S, Benech C, Viora-Dupont E, Mau-Them F, Rondeau S, Elsharkawi I, Granadillo J, Neidich J, Soares C, Tkachenko N, Amudhavalli S, Engleman K, Boland A, Deleuze J, Bezieau S, Odent S, Toutain A, Bonneau D, Gilbert-Dussardier B, Faivre L, Rio M, Marechal C, Ferec C, Repnikova E, Cao Y. Heterozygous HMGB1 loss-of-function variants are associated with developmental delay and microcephaly Clin Genet. 2021. doi:10.1111/cge.14015 PMID:34164801 ( International collaboration) |
Sams E, Ng J, Tate V, Hou Y, Cao Y, Antonacci-Fulton L, Belhassan K, Neidich J, Mitra R, Cole F, Dickson P, Milbrandt J, Turner T. From karyotypes to precision genomics in 9p deletion and duplication syndromes. HGG Adv. 2021 Dec 24;3(1):100081. doi: 10.1016/j.xhgg.2021.100081. PMID: 35047865 |
Lai A, Soucy A, Achkar C, Barkovich A, Cao Y, DiStefano M, Evenson M, Guerrini R, Knight D, Lee Y, Mefford H, Miller D, Mirzaa G, Mochida G, Rodan L, Patel M, Smith L, Spencer S, Walsh C, Yang E, Yuskaitis C, Yu T, Poduri A. The ClinGen Brain Malformation Variant Curation Expert Panel: Rules for Somatic Variants in AKT3, MTOR, PIK3CA and PIK3R2. Genet Med. 2022 Aug 22;S1098-3600(22)00871-1. doi: 10.1016/j.gim.2022.07.020. PMID: 35997716 |
Belhassan K, Saadalla A, Hoppman N, Lee Y, Abboud C, Webley M, Koon S, Neidich J, Cao Y. ETV6/FLT3 fusion gene detected in a patient with T-cell lymphoblastic lymphoma. CAP TODAY. Case Report, 2022 April. |
Hou Y, Evenson M, Corliss M, Mahapatra L, Aldawood A, Krysiak K, Schroeder M, Heusel J, Neidich J, Cao Y. A Comparative Analysis of RAS Variants in Patients with Disorders of Somatic Mosaicism. Genet Med. 2022 Nov 29;S1098-3600(22)01036-X. doi: 10.1016/j.gim.2022.11.016. PMID: 36571464 |
Assistant
Dani Salazar
314-362-2975
sdaniela@wustl.edu