Susan Gilfillan, PhD

Associate Professor, Pathology & Immunology


  • BA in Biology/English: University of Denver, Denver, Colorado (1982)
  • PhD: Stanford University School of Medicine, Stanford, California (1990)
  • Postdoctoral Fellow: Institut de Chimie Biologique, Strasbourg /I.G.B.M.C. Illkirch, France (1995)
  • Member: Basel Institute for Immunology, Basel, Switzerland (2001)

Research Interests

For most of my research career, I have focused on generating genetically engineered mice. Much of this work has involved gene targeting in embryonic stem (ES) cells, including the generation of germline competent ES cells from C57BL/6J mice as part of ongoing efforts to make the process more efficient in this commonly used inbred strain of mice.

Like most, our lab is now using CRISPR technology to genetically engineer mice; we also generate conventional and BAC transgenic mice and routinely obtain mice from other laboratories, repositories (KOMP), and commercial sources. Given this, a major aspect of my current work in the lab is to design and implement genotyping protocols as well as plan/carry out breeding programs that produce experimental cohorts of mice with the required genotypes that are adequately controlled for environmental factors, particularly the microbiota.

Editorial Responsibilities

Ad hoc Reviewer Journal of Immunology
Ad hoc Reviewer Journal of Experimental Medicine
Ad hoc Reviewer Arthritis & Rheumatology

Service to the Univerity


Lecture on animal (mouse) genetics/transgenics for the Summer Bench Fundamentals class


Kelly Antolik

Lab phone: 314-362-0368
Office location: BJC-IH Building, Office Suite B 8210