
Simone Brioschi, PhD
Assistant Professor, Pathology & Immunology
Contact
- Email: s.brioschi@wustl.edu
- Phone: 314-362-0368
Division: Immunobiology
Education
MS: Biotechnology, University of Milano-Bicocca, Italy
PhD: Biology, University of Freiburg, Germany
Specializations
Neuroimmunology
Recognition
Alzheimer’s Association Research Grant (AARG-24-1292984)
2023 O’Leary Prize Competition
Research Interests
My research focuses on CNS-resident immune cells in the brain parenchyma, meninges, and choroid plexus. I aim to elucidate their origin, developmental mechanisms, and interactions with other brain cells in homeostasis, as well as their phenotypic changes and immune responses in disease.
Selected Publications
Drivers and shapers of macrophages specification in the developing brain
Publication
Mechanisms and environmental factors shaping the ecosystem of brain macrophages
Publication
Neoantigen-specific cytotoxic Tr1 CD4 T cells suppress cancer immunotherapy
Publication
An inducible genetic tool to track and manipulate specific microglial states reveals their plasticity and roles in remyelination
Publication