Division
- Anatomic & Molecular Pathology
Education
- MD, Shanghai Jiao Tong University, School of Medicine, China
- PhD, Cellular and Molecular Biology, Karolinska Institute, Sweden
- Residency, Anatomic Pathology, University of Massachusetts School of Medicine
- Fellowship, Oncologic Surgical Pathology, Memorial Sloan Kettering Cancer Center
- Fellowship, Genitourinary Pathology, Indiana University
Board Certifications
- Anatomic Pathology
Clinical Interest
- Genitourinary Pathology
Research Interests
- Prostate Cancer; Kidney Cancer; Bladder Cancer; Other Common Urological Diseases
Selected Publications
| Ge R, Wang Z, Cheng L. Tumor microenvironment heterogeneity an important mediator of prostate cancer progression and therapeutic resistance. Nature NPJ Precis Oncol. 2022 May 4;6(1):31. |
| Ge R, Wang Z, Montironi R., Jiang Z., Cheng M., Santoni M., Huang K., Massari F., Lu X., Cimadamore A., Lopez-Beltran A., Cheng L. Epigenetic modulations and lineage plasticity in advanced prostate cancer. Ann Oncol. 2020 Apr;31(4):470-479 |
| Wang Z. Deng T., Long X, Lin X, Wu S., Wang H., Ge R., Zhang Z., Wu C., Taplin M., Olumi AF. Methylation of SRD5A2 promoter predicts a better outcome for castration-resistant prostate cancer patients undergoing androgen deprivation therapy. PLoS One. 2020 Mar 5;15(3): |
| Wang Z, Hu L, Salari K, Bechis S, Ge R, Wu S, Rassoulian C, Pham J, Wu CL, Tabatabaei S, Douglas SW, Olumi AF. Androgenic to estrogenic switch in human adult prostate gland is regulated by epigenetic silencing of steroid 5α-reductase 2. J Pathol. 2017 Sep 20. |
| Olumi AF, Wang, Z, Ge R, Wu S, Wu CJ. Epigenetic silencing and variable expression of SRD5A2 in specific compartmenrs of human prostate. Journal of Clinical Oncology 34 (2_suppl):38-38 · January 2016 |
| Ge R, Wang Z, Wu S, Zhuo Y, Otsetov A, Cai C, Zhong W, Wu C, Olumi A. Metformin represses cancer cells via alternate pathways in N-Cadherin Expressing vs. N-Cadherin deficient cells. Oncotarget 2015 Oct 6;6(30):28973-87. |
| Ge R, Wang Z, Bechis SK, Otsetov AG, Hua S, Wu S, Wu CL, Tabatabaei S, Olumi AF. DNA Methyl Transferase 1 Reduces Expression of 5-alpha Reductase 2 in the Aging Adult Prostate, American Journal of Pathology. 2015; 185:870-82. |
| Preston MA, Wilson KM, Markt SC, Ge R, Morash C, Stampfer MJ, Loda M, Giovannucci E, Mucci LA, Olumi AF. 5α-Reductase inhibitors and risk of high-grade or lethal prostate cancer. JAMA Intern Med. 2014 Aug; 174(8):1301-7. |
| Wang Z, Cheng Z, Cristofaro V, Li J, Xiao X, Gomez P, Ge R, Gong E, Strle K, Sullivan MP, Adam RM, White MF, Olumi AF. Inhibition of TNF-α improves the bladder dysfunction that is associated with type 2 diabetes. Diabetes, 2012; 61(8):2134-45. |
| Ge R, Wang Z, Zeng Q, Xu X, Olumi AF. F-box protein 10, an NF-κB-dependent anti- apoptotic protein, regulates TRAIL-induced apoptosis through modulating c-Fos/c-FLIP pathway. Cell Death Differ. 2011 Jul;18(7):1184-95. |
Assistant
Charlsey Robinson
charlsey.robinson@wustl.edu
314-454-8462
BJC-IOH Room 3422