
Nidhi Rohatgi, PhD
Assistant Professor, Pathology & Immunology
Contact
- Email: nidhirohatgi@wustl.edu
- Phone: 314-454-5085
Division: Anatomic & Molecular Pathology
Education
BS: Delhi University, New Delhi, India
Masters, Biotechnology: Hamdard University, New Delhi, India
PhD, Biochemistry: All India Institute of Medical Sciences, New Delhi, India
Recognition
ASBMR Young Investigator Award, American Society for Bone and Mineral Research, 2014
Travel Award, Musculoskeletal Research Symposium, Washington University-School of Medicine, 2016
Best Investigator Award, American Society for Bone and Mineral Research, 2016
Travel Award, American Society for Bone and Mineral Research, 2017
Investigator Award, Musculoskeletal Research Symposium, Washington University-School of Medicine, 2019
Travel Award, American Society for Bone and Mineral Research, 2021
Travel Award, American Society for Bone and Mineral Research, 2023
Mid-Career Faculty Travel Grant, American Society for Bone and Mineral Research, 2024
Research Interests
My research aims to exploring how cellular immune-metabolism regulates obesity and skeletal health. Specifically investigating how chromatin modifications influence the metabolic state of macrophages to adopt a homeostatic or inflammatory role in various diseases, including obesity and inflammatory arthritis. By integrating metabolomics and genomics, my work seeks to elucidate how the epigenetic-metabolic axis regulates macrophage inflammatory functions. This research will provide new insights into how macrophage metabolic states are controlled and could lead to the identification of effective therapeutic targets for inflammatory diseases.
Selected Publications
Depletion of marrow adipo-CAR cells in mice enhances bone formation by activating bone morphogenetic protein receptor (BMPR) in pre-osteoblasts
Publication
Tmem178 Negatively Regulates IL-1β Production Through Inhibition of the NLRP3 Inflammasome
Publication
BAP1 promotes osteoclast function by metabolic reprogramming
Publication
ThPOK inhibits osteoclast formation via NFATc1 transcription and function
Publication