Mark A. Zaydman, MD, PhD

Mark A. Zaydman, MD, PhD

Assistant Professor, Pathology & Immunology

 

Division

  • Laboratory & Genomic Medicine

Education

  • BSE, Biomedical Engineering (Summa Cum Laude): Case Western Reserve University, Cleveland, Ohio (2007)
  • MD, Washington University School of Medicine, St. Louis, Missouri (2016)
  • PhD, Biomedical Engineering: Washington University in St. Louis, St. Louis, MO (2016)
  • Residency, Clinical Pathology: Barnes Jewish Hospital (2019)

Subspecialization

  • Clinical Pathology

Recognition

  • Presidential Scholarship Award, Case Western Reserve University (2003-2007)
  • Alumni Association Scholarship Award, Case Western Reserve University (2004-2007)
  • Deans Honor List, Case Western Reserve University (2003-2006)
  • Outstanding Sophomore Award, Case School of Engineering, Case Western Reserve University (2005)
  • Outstanding Junior Award, Case School of Engineering, Case Western Reserve University (2006)
  • Undergraduate Research Fellowship, American Heart Association (2006)
  • Chairman Award, Department of Biomedical Engineering, Case Western Reserve University (2007)
  • Best Talk Award, Medical Scientist Training Program, Annual Retreat, Washington University in St. Louis (2011)
  • Predoctoral Research Fellowship, American Heart Association (2011)
  • Best Poster Award, Department of Biochemistry and Biophysics, Annual Retreat, Washington University in St. Louis (2013)
  • T32 Appointment, NIH Training Grant, Washington University in St. Louis (2013-2014) Best Poster Award (Predoctoral Category), School of Medicine, Cardiovascular Research Day, Washington University in St. Louis (2013)
  • Spencer T. and Ann W. Olin Fellowship, “For past achievement and the promise of a distinguished career in the biomedical sciences”, Medical Scientist Training Program, Washington University in St. Louis (2015)
  • Best Trainee Oral Presentation Award, Division of Lab and Genomic Medicine, Grand Rounds, Washington University in St. Louis (2017)
  • Paul. E. Strandjord Young Investigator Award, Academy of Clinical Laboratory Physicians and Scientists (2017, 2019, 2020)
  • Distinguished Abstract Award, American Association for Clinical Chemistry, Annual Meeting (2019)
  • William Roberts Young Investigator Award with Distinction, Academy of Clinical Laboratory Physicians and Scientists (2021)
  • Outstanding Junior Faculty Paper of the Year Award (Laboratory Medicine), Department of Pathology and Immunology, WashU Medicine, Saint Louis, Missouri (2023)
  • Outstanding Scientific Achievements by a Young Investigator, Association for Diagnostic and Laboratory Medicine, Washington, DC (2024)
  • Outstanding Achievements in Quality Improvement Award, Department of Pathology and Immunology, WashU Medicine, Saint Louis, Missouri (2024)

Clinical Interests

  • Clinical informatics
  • Clinical decision support
  • Data analytics
  • Laboratory test utilization

Research Interests

  • Applications of data analytics in laboratory medicine
  • Responsible use of artificial intelligence in laboratory medicine
  • Detection and prevention of errors in laboratory testing
  • Measurement and benchmarking of laboratory test value
  • Fairness and equity in laboratory medicine

Selected Publications

Azimi V, Zaydman MA. Optimizing Equity: Working towards Fair Machine Learning Algorithms in Laboratory Medicine. J Appl Lab Med. 2023 Jan 4;8(1):113-128. doi:10.1093/jalm/jfac085. PMID: 36610413. 
Spies NC, Hubler Z, Azimi V, Zhang R, Jackups R Jr, Gronowski AM, Farnsworth CW,Zaydman MA. Automating the Detection of IV Fluid Contamination Using UnsupervisedMachine Learning. Clin Chem. 2023 Dec 12:hvad207. doi: 10.1093/clinchem/hvad207. Epubahead of print. PMID: 38084963. 
Spies NC, Militello L, Farnsworth CW, El-Khoury JM, Durant TJS, Zaydman MA. Prospective and External Validation of an Ensemble Learning Approach to Sensitively Detect Intravenous Fluid Contamination in Basic Metabolic Panels, Clinical Chemistry, 2024;, hvae168
Azimi V, Slade M, Fiala M, Fortier JM, Stockerl-Goldstein K, Frater JL, Brestoff JR, Jackups R, Zaydman MA. A Single Reference Interval for Interpreting Serum Free Light Chains across Patients with Varying Renal Function. Clin Chem. 2023 May 6:hvad043. doi: 10.1093/clinchem/hvad043. Epub ahead of print. PMID: 37147848.
Azimi V, Fiala M, and Zaydman MA. Use of the Current Standard of Practice Serum Free Light Chains (sFLC) Reference Interval Puts Black Patients at 5 Times Higher Odds for Light Chain Monoclonal Gammopathy of Undetermined Significance (LC-MGUS), Clinical Chemistry, 2023;, hvad083, https://doi.org/10.1093/clinchem/hvad083
Zaydman MA, Little AS, Haro F, Aksianiuk V, Buchser WJ, DiAntonio A, Gordon JI, Milbrandt J, Raman AS. Defining hierarchical protein interaction networks from spectral analysis of bacterial proteomes. Elife. 2022 Aug 17;11:e74104. doi: 10.7554/eLife.74104. PMID: 35976223; PMCID: PMC9427106.

Assistant
Dionne Brierton
314-362-3186
bdionne@wustl.edu
BJCIH Room 4410