Professor, Pathology & Immunology

Division: Immunobiology

Education

MD, University of Genova, Italy, Medicine and Surgery, 1989

University of Genova, Italy, specialization in Medical Microbiology and Virology, 1993

Research Fellow, Laboratory of Immunogenetics, National Institute for Cancer Research, Genova, Italy, 1989-1994

Visiting Scientist, Basel Institute for Immunology, Basel, Switzerland, 1994

Member of The Basel Institute for Immunology, Basel, Switzerland, 1995-2001

DBBS Affiliation

Immunology Program

Editorial Responsibilities

Section Editor, Journal of Immunology, 2020-present

Editor, Frontiers in HIV: 2007-present

Reviewer, Nature, Nature Immunology, Journal of Experimental Medicine, Journal of Immunology, European Journal of Immunology: Ad hoc

Service to the Department

Director of the Pathology & Immunology Flow Cytometry Core Facility: 2006-present

Research Interests

My interest in the last 20 years has been to study how innate immune cells, in particular Dendritic Cells (DCs), NK cells and emerging subsets of Innate Lymphoid Cells (ILCs), respond to pathogens and how these responses are altered or can be manipulated in human diseases. My research focuses on 3 fields: 1) plasmacytoid DCs (pDCs) as a primary source of Type I interferon in response to viruses and implication of pDCs in human autoimmune diseases; 2) regulation of NK cell function by activating and inhibitory receptors; 3) ILC diversity in mucosal tissues.


Selected Publications


Assistant

Administrative Professional

Lab Phone: 314-362-0368
Office Location: BJC-IH Building, Office Suite B 8210