
Marina Cella, MD
Professor, Pathology & Immunology
Contact
- Email: mcella@wustl.edu
Division: Immunobiology
Education
MD, University of Genova, Italy, Medicine and Surgery, 1989
University of Genova, Italy, specialization in Medical Microbiology and Virology, 1993
Research Fellow, Laboratory of Immunogenetics, National Institute for Cancer Research, Genova, Italy, 1989-1994
Visiting Scientist, Basel Institute for Immunology, Basel, Switzerland, 1994
Member of The Basel Institute for Immunology, Basel, Switzerland, 1995-2001
DBBS Affiliation
Immunology Program
Editorial Responsibilities
Section Editor, Journal of Immunology, 2020-present
Editor, Frontiers in HIV: 2007-present
Reviewer, Nature, Nature Immunology, Journal of Experimental Medicine, Journal of Immunology, European Journal of Immunology: Ad hoc
Service to the Department
Director of the Pathology & Immunology Flow Cytometry Core Facility: 2006-present
Research Interests
My interest in the last 20 years has been to study how innate immune cells, in particular Dendritic Cells (DCs), NK cells and emerging subsets of Innate Lymphoid Cells (ILCs), respond to pathogens and how these responses are altered or can be manipulated in human diseases. My research focuses on 3 fields: 1) plasmacytoid DCs (pDCs) as a primary source of Type I interferon in response to viruses and implication of pDCs in human autoimmune diseases; 2) regulation of NK cell function by activating and inhibitory receptors; 3) ILC diversity in mucosal tissues.
Selected Publications
Rorγt-positive dendritic cells are required for the induction of peripheral regulatory T cells in response to oral antigens
Publication
Tissue-resident CCR2<sup>+</sup> macrophage TREM-1/3 signaling is necessary for monocyte and neutrophil recruitment to injured hearts
Publication
Mapping of RORγt<sup>+</sup> dendritic cells in human tissues establishes their preferential niche in adult lymph nodes
Publication
Mucosal Single-Cell Profiling of Crohn's-Like Disease of the Pouch Reveals Unique Pathogenesis and Therapeutic Targets
Publication
Assistant

Lab Phone: 314-362-0368
Office Location: BJC-IH Building, Office Suite B 8210