Marianna Ruzinova, MD, PhD

Marianna Ruzinova, MD, PhD

Professor, Pathology & Immunology
Section Head, Hematopathology
Director, Immunohistochemistry

Division

  • Anatomic & Molecular Pathology

Additional Titles

  • Director, Immunohistochemistry

Clinical Interests

  • Autopsy
  • GI & Pancreatic Pathology
  • Hematopathology
  • Liver Pathology

Selected Publications

DUSP6 mediates resistance to JAK2 inhibition and drives leukemic progression. Kong T, Laranjeira ABA, Yang K, Fisher DAC, Yu L, Poittevin De La Frégonnière L, Wang AZ, Ruzinova MB, Fowles JS, Fulbright MC, Cox MJ, Celik H, Challen GA, Huang S, Oh ST.Nat Cancer. 2023 Jan;4(1):108-127. doi: 10.1038/s43018-022-00486-8. Epub 2022 Dec 29.PMID: 36581736
SOX9 Expression Is Superior to Other Stem Cell Markers K19 and EpCAM in Predicting Prognosis in Hepatocellular Carcinoma. Ruzinova MB, Ma C, Brunt EM, Goss CW, Vachharajani N, Chapman WC, Liu TC.Am J Surg Pathol. 2023 Jan 1;47(1):1-11. doi: 10.1097/PAS.0000000000001990. Epub 2022 Nov 3.PMID: 36322988
Distinct clonal identities of B-ALLs arising after lenolidomide therapy for multiple myeloma. Barnell EK, Skidmore ZL, Newcomer KF, Chavez M, Campbell KM, Cotto KC, Spies NC, Ruzinova MB, Wang T, Abro B, Kreisel F, Parikh BA, Duncavage EJ, Frater JL, Lee YS, Hassan A, King JA, Kohnen DR, Fiala MA, Welch JS, Uy GL, Vij K, Vij R, Griffith M, Griffith OL, Wartman LD.Blood Adv. 2023 Jan 24;7(2):236-245. doi: 10.1182/bloodadvances.2022007496.PMID: 36251745
IRAK4 Signaling Drives Resistance to Checkpoint Immunotherapy in Pancreatic Ductal Adenocarcinoma. Somani VK, Zhang D, Dodhiawala PB, Lander VE, Liu X, Kang LI, Chen HP, Knolhoff BL, Li L, Grierson PM, Ruzinova MB, DeNardo DG, Lim KH.Gastroenterology. 2022 Jun;162(7):2047-2062. doi: 10.1053/j.gastro.2022.02.035. Epub 2022 Mar 7.PMID: 35271824
Decitabine salvage for TP53-mutated, relapsed/refractory acute myeloid leukemia after cytotoxic induction therapy. Ferraro F, Gruszczynska A, Ruzinova MB, Miller CA, Percival ME, Uy GL, Pusic I, Jacoby MA, Christopher MJ, Kim MY, Westervelt P, Cashen AF, Schroeder MA, DiPersio JF, Abboud CN, Wartman LD, Gao F, Link DC, Ley TJ, Welch JS.Haematologica. 2022 Jul 1;107(7):1709-1713. doi: 10.3324/haematol.2021.280153.PMID: 35236053
The MK2/Hsp27 axis is a major survival mechanism for pancreatic ductal adenocarcinoma under genotoxic stress. Grierson PM, Dodhiawala PB, Cheng Y, Chen TH, Khawar IA, Wei Q, Zhang D, Li L, Herndon J, Monahan JB, Ruzinova MB, Lim KH.Sci Transl Med. 2021 Dec;13(622):eabb5445. doi: 10.1126/scitranslmed.abb5445. Epub 2021 Dec 1.PMID: 34851698

Assistant
Jill Guess
314-362-0108
jill.guess@wustl.edu
BJCIH Room 3422