Joseph C. Corbo, MD, PhD

Professor, Pathology & Immunology

Divisions

Neuropathology

Corbo Lab

Division: Neuropathology

Research Interests: The development, diseases, and evolution of photoreceptors

Titles

Professor, Genetics
Professor, Ophthamology and Visual Sciences

Education

PhD, Biology: U.C. San Diego, La Jolla, CA (1997)

Medical Degree: U.C. San Diego, La Jolla, CA (1999)

Resident in Anatomic Pathology: Brigham and Women’s Hospital, Boston, MA (2001)

Clinical Fellow in Neuropathology: Brigham and Women’s Hospital, Boston, MA (2003)

Research Post-doctoral Fellow, Department of Genetics: Harvard Medical School, Boston, MA (2005)

Boards

Neuropathology: Board Certified

Anatomic Pathology: Board Certified

Recognition

Japan Society for Promotion of Science, short-term fellowship (Kyoto, Japan), 1997

Medical Scientist Training Program, U. C. San Diego, 1992 – 1999

Regents Scholarship, University of California, 1991

Lucille P. Markey Charitable Trust Fellowship, 1992 – 1996

Firestone Medal for Outstanding Undergraduate Honors Thesis, Stanford University, 1990

Award for Academic Excellence in the Freshman Year, Stanford University, 1987

Red Bird

Research Interests

We are poised on the threshold of a new era in medicine in which whole-genome sequencing will be a clinical reality. One of our lab’s major goals is to leverage this revolution in sequencing technology to predict and prevent disease. Up to now, our approach has been to elucidate the architecture of the transcriptional networks of the retina, with a particular focus on photoreceptors. We utilize this knowledge to build new technologies for mapping genotype onto phenotype and to devise cellular reprogramming strategies and optogenetic approaches to treat retinal disease. These translational strategies for retinal disease are complemented by other studies in the lab that focus on the basic biology of photoreceptors. Our research is strongly interdisciplinary and collaborative, with current projects that lie at the intersection of photoreceptor biology with chemistry and physics. By combining both basic and translational approaches, our lab aims to achieve a systems-level understanding of the development, diseases, function, evolution, and diversity of photoreceptors, and to extend this approach to other organ systems.

Selected Publications

WashU Medicine Profile

Assistant

Jaden Mocumbi

Administrative Professional