Ian S. Hagemann, MD, PhD

Associate Professor, Pathology & Immunology
Associate Professor, Obstetrics and Gynecology

Additional Titles

  • Associate Director, Selective (Surgical) Pathology Fellowship
  • Program Director, Gynecologic and Breast Pathology Fellowship

Education

  • PhD, Washington University, St. Louis, MO (2008)
  • MD, Washington University, St. Louis, MO (2008)
  • A.B., Princeton University (2000), Chemistry, certificate in French Language and Culture
  • Surgical Pathology Fellowship: Washington University, St. Louis (2012)
  • Molecular Genetic Pathology Fellowship: Washington University, St. Louis (2013)

Board Certifications

  • 2019 – Board Certification in Clinical Informatics
  • 2014 – Certificate of Qualification as Laboratory Director, New York State Department of Health (histopathology—general; oncology—molecular and cellular tumor markers)
  • 2014 – Physician, Illinois State Medical Licensing Board
  • 2011 – Physician and Surgeon, Missouri Board of Healing Arts
  • 2013 – Pathology—Molecular Genetic, American Board of Pathology and American Board of Medical Genetics
  • 2011 – Pathology—Anatomic, American Board of Pathology

Recognition

  • 2019 – Academy of Educators, WUSM
  • 2019 – Distinguished Service Teaching Award from the Class of 2021, WUSM
  • 2018 – Distinguished Service Teaching Award from the Class of 2020, WUSM
  • 2015 – Distinguished Service Teaching Award from the Class of 2017, WUSM
  • 2013 – Distinguished Service Teaching Award from the Class of 2015, WUSM
  • 2011 – Surgical Pathology Innovation Award, Department of Pathology and Laboratory Medicine, University of Pennsylvania
  • 2011 – Leonard Berwick Residency Teaching Award, Department of Pathology and Laboratory Medicine, University of Pennsylvania

Clinical Interests

  • Autopsy
  • Breast Pathology
  • Gynecological Pathology
  • Molecular Genetic Pathology

Research Interests

My research relates to clinicopathologic correlations, prognostic factors and biomarkers in gynecologic, breast, and soft tissue pathology. I serve as the local reference pathologist for Gynecologic Oncology Group and other trials, triaging biospecimens for translational research as well as study qualification. In a collaboration with Ting Wang (Genetics), I am investigating the genetic and epigenetic basis of endometrial cancer and of uterine carcinosarcoma, a variant of endometrial cancer that accounts for a disproportionate share of mortality. Using laser capture microdissection, we have separated the two components of the tumor (carcinomatous and sarcomatous) and identified distinctive epigenetic differences between them. Another concern related to carcinosarcoma is that it is not currently possible to predict which patients will be long-term survivors. We will determine whether testing for specific combinations of mutations and epimutations in the tumor can predict those who will survive or those who will respond to chemotherapy. In a separate set of projects, I am interested in studying the clinical implementation of next-generation sequencing to delineate its role in cancer diagnosis, prognosis, and prediction.

Service to the Department

  • 2018 – Present: Anatomic Pathology didactics organizer
  • 2017 – Present: Chair of the AP/CP Residency Clinical Competency Committee, BJH
  • 2014 – Present: Anatomic and Molecular Pathology Conference Award Committee
  • 2014 – 2017: Serve as clinical liaison for soft tissue and bone pathology
  • 2014 – 2019: Serve as supervisor of pathologists’ assistants
  • 2013 – Present: Associate director of Selective (Surgical) Pathology fellowship program (5 trainees/year)
  • 2013 – Present: Reference pathologist for gynecologic oncology trial eligibility, WUSM
  • 2012 – Present: Section head for gynecologic pathology in WUMS 2 pathology course (teach 8.5 lecture hours, 3 lab hours/year)

Service to the University

  • 2013 – Present: Member, Committee on Admissions, WUSM; 2016 – Present, Chair of the South Subcommittee
  • 2014 – 2015: Research and Graduate Education Committee, WUSM LCME Self-Study
  • 2014 – 2017: Member, Executive Council of the Washington University Medical Center Alumni Association
  • 2014 – 2019: Serve as supervisor of pathologists’ assistants (four)
  • 2014 – 2017: Clinical liaison for bone & soft tissue
  • 2020-2021: Gateway Curriculum Content Expert for the Basic-Clinical Science Integration Curriculum Design Team

Publications


Assistant
Charlsey Robinson
314-454-8462
charlsey.robinson@wustl.edu