
Hussein Sultan, PhD
Assistant Professor, Pathology & Immunology
Contact
- Email: hsultan@wustl.edu
- Phone: 314-273-2077
Division: Immunobiology
Titles
Office of Faculty Development Representative
Research Interests
My utmost motivation lies in enhancing the safety and effectiveness of cancer immunotherapy, with specific emphasis on personalized neoantigen cancer vaccines.
My research focuses on two main areas:
Define the intrinsic and extrinsic factors that lead to the induction/development of type 1 regulatory T cells and unravel the mechanisms involved in their suppressive activity.
Develop novel vaccination strategies that promote the induction of effector anti-tumor T cells while avoiding the generation of suppressive T-cell responses that promote tumor progression.
Selected Publications
STAT5 Activation Enhances Adoptive Therapy Combined with Peptide Vaccination by Preventing PD-1 Inhibition
Publication
Improvement of Tumor Neoantigen Detection by High-Field Asymmetric Waveform Ion Mobility Mass Spectrometry
Publication
Neoantigen-specific cytotoxic Tr1 CD4 T cells suppress cancer immunotherapy
Publication
IL2 Targeted to CD8<sup>+</sup> T Cells Promotes Robust Effector T-cell Responses and Potent Antitumor Immunity
Publication
Assistant

Lab Phone: 314-362-8746
Office Location: BJC-IH Building, Office Suite C 8417