
Hussein Sultan, PhD
Assistant Professor, Pathology & Immunology
Contact
- Email: hsultan@wustl.edu
- Phone: 314-273-2077
Titles
Office of Faculty Development Representative
Research Interests
My utmost motivation lies in enhancing the safety and effectiveness of cancer immunotherapy, with specific emphasis on personalized neoantigen cancer vaccines.
My research focuses on two main areas:
Define the intrinsic and extrinsic factors that lead to the induction/development of type 1 regulatory T cells and unravel the mechanisms involved in their suppressive activity.
Develop novel vaccination strategies that promote the induction of effector anti-tumor T cells while avoiding the generation of suppressive T-cell responses that promote tumor progression.
Selected Publications
CD4<sup>+</sup> T Cells Play Distinct Roles during the Priming versus Effector Phases of Immune Checkpoint Therapy–Dependent Tumor Elimination by CD8<sup>+</sup> T Cells
Publication
mRNA vaccines engage unconventional pathways in CD8<sup>+</sup> T cell priming
Publication
Cancer Neoantigen Vaccines Emerge Efficacious
Publication
STAT5 Activation Enhances Adoptive Therapy Combined with Peptide Vaccination by Preventing PD-1 Inhibition
Publication
Assistant

Lab Phone: 314-362-8746
Office Location: BJC-IH Building, Office Suite C 8417