Erika C. Crouch, MD, PhD

Professor, Pathology & Immunology

Divisions

Anatomic and Molecular Pathology

Titles

Carol B. and Jerome T. Loeb Professor of Medical Education
Vice Chair for Education
Gateway Histology and Pathology Thread Leader
Gateway Module 2 Phase 1 Co-leader

Education

MD/PhD: University of Washington, Seattle, Washington (1978-79)

Postdoctoral Research Fellow, Department of Biochemistry: University of Washington, Seattle, Washington (1979)

Resident in Anatomic Pathology, Department of Pathology: University of Washington, Seattle, Washington (1982)

Parker B. Francis Fellow in Pulmonary Pathology, Department of Pathology: University of British Columbia, Vancouver, Canada (1983)

Boards

Anatomic Pathology, American Board of Pathology with recertification

Recognition

Gateway Distinguished Service Awards: 2022, 2023
Gateway Thread Leader of the Year Award: 2024

WUSM Second Century Award: 2016

Preclinical Professor of the Year Award: 2011, 2014, 2018, 2019

Goldstein Leadership Award in Medical Student Education (awarded by faculty): 2002

WUSM Academy of Educators: 2019

Distinguished Faculty Award from WU Alumni Association (awarded by alumni): 2001

Birthplace of Surfactant Protein D – Former Lab Website

WashU Medicine Research Profile

Service to the University

2021- present
Histology and Pathology Thread Leader, Gateway Curriculum

2020-present
Phase 1 Module 2 Co-Leader (Defense and Response to Injury), Gateway Curriculum

2010-2020
Founding Director of Anatomic and Molecular Core Labs (CAP-CLIA certified)

2009-2010
President of WUSM Chapter of AOA

2004-2020
Chair, Goldstein Leadership in Education Committee (Appointed by Dean)

DBBS Graduate Program Affiliations

Biochemistry
Developmental, Regenerative and Stem Cell Biology Developmental
Molecular Cell Biology

Research Interests

Our past research focused on the structure and function of collagenous carbohydrate-binding proteins known as collectins. We identified and subsequently characterized the structure, biosynthesis, tissue localization, genomic regulation, and functions of Surfactant Protein D (SP-D) – a collectin that plays important roles in the innate pulmonary host defense against a wide variety of important bacterial, fungal, and viral pathogens. Most recently, the laboratory employed site-directed mutagenesis and crystallographic analysis to examine mechanisms of viral pattern recognition, including interactions with the hemagglutinin of influenza A. This lead to the creation of mutants with enhanced anti-IAV activity in animal models.

Selected Publications

WashU Medicine Profile

Assistant

Charlsey Robinson

Administrative Assistant II