Bijal Parikh, MD, PhD

Assistant Professor, Pathology & Immunology

Phone: 314-273-7926
Email: bparikh@wustl.edu

Additional Titles

Medical Director, Molecular Diagnostics Laboratory
Associate Medical Director, Molecular Infectious Disease Laboratory
Associate Medical Director, HLA Laboratory
Associate Program Director, Molecular Genetic Pathology Fellowship

Education

BS: Rutgers University, New Brunswick, NJ (1998)
PhD: Rutgers University, New Brunswick, NJ (2004)
MD: Robert Wood Johnson Medical School-Rutgers University, Piscataway, NJ (2006)
Residency, Clinical Pathology: Washington University, St. Louis, MO (2010)
Fellowship, Molecular Genetic Pathology: Washington University, St. Louis, MO (2018)

Board Certifications

Missouri Medical License
American Board of Pathology in Clinical Pathology, 2011
American Board of Pathology in Molecular Genetic Pathology, 2019

Recognition

Outstanding Research Award in Molecular Pathology/Pharmacogenomics, American Association for Clinical Chemistry Annual Meeting, 2009
Paul E. Strandjord Young Investigator Award, Academy of Clinical Laboratory Physicians and Scientists Annual Meeting, 2009, 2010
Infectious Diseases Training Grant (T32-A1007172), 2010
Rheumatology Training Grant (T32-AR007279), 2011-2012
Chair’s Special Recognition Award, COVID Clinical Hero, Washington University Department of Pathology and Immunology, 2020
Outstanding Achievements in Quality Improvement Award, Washington University Department of Pathology and Immunology, 2020

Research Interests

My clinical research centers on aspects of laboratory testing involving viral, immunologic, and molecular diagnostics, with a specific focus on the implementation of next-generation sequencing approaches. My basic science interests explore mechanisms governing host-pathogen interactions with ongoing research projects around the development of a murine cytomegalovirus model study innate immune control by natural killer cells and trafficking of virus during neonatal infection.

Publications

PubMed Search

Selected Publications:

Raju S., Anderson N.W., Robinson E., Squires C., Wallace M.A., Burnham C.D, and Parikh B.A. Comparison of Six SARS-CoV-2 Molecular Methods and Correlation with the Cycle Threshold Distribution in Clinical Specimens. J Appl Lab Med. 2021 Jul 20:jfab086.

Parikh, B.A. and Farnsworth W.C. Laboratory evaluation of SARS-CoV-2 in the COVID-19 pandemic. Best Pract Res Clin Rheumatol, 2021. 101660. doi: 10.1016/j.berh.2021.101660. PMID: 33518410

Tahan S., Parikh B.A., Droit L, Wallace M., Burnham C.D., and Wang D. SARS-CoV-2 E gene variant alters analytical sensitivity characteristics of viral detection using a commercial RT-PCR assay. J. Clin. Microbiol. 2021. 59(7):e0007521. PMID: 33903167

Parikh B.A., Bern M.D., Piersma S.J., Yang L., Beckman D.L., Poursine-Laurent J., Plougastel-Douglas B., and Yokoyama W.M. Control of viral infection by natural killer cell inhibitory receptors. Cell Rep. 2020. 32:107969. PMID: 32726632

Parikh B.A., Love-Gregory L., Duncavage E.J., and Heusel J.W. Identification of challenges and a framework for implementation of the AMP/ASCO/CAP classification guidelines for reporting somatic variants. 2020. Pract Lab Med. 21:e00170. PMID: 32548229

Liu C., Duffy B.F., Weimer E.T., Montgomery M.C., Jennemann J.E., Hill R., Phelan D., Lay L., Parikh B.A. Performance of a multiplexed amplicon-based next-generation sequencing assay for HLA typing. PLoS One. 2020;15:e0232050. PMID: 32324777

Parikh B.A., Piersma S.J., Pak-Wittel M.A., Yang L., Schreiber R.D., and Yokoyama W.M. Dual requirement of cytokine and activation receptor triggering for cytotoxic control of murine cytomegalovirus by NK cells. PLoS Pathog. 2015 11:e1005323. PMID: 26720279

Parikh, B.A., Beckman, D.L., Patel, S.J., White, J.M., and Yokoyama, W.M. Detailed phenotypic and molecular analyses of genetically modified mice generated by CRISPR-Cas9-mediated editing. PLoS One. 2015; 10:e0116484. PMID: 25587897

Assistant
Christine Berry
314-362-2207
berryc@wustl.edu
Office Location: LGM, Suite 5806