
Alexey Sergushichev, PhD
Assistant Professor, Pathology and Immunology
Contact
- Email: asergushichev@wustl.edu
- Phone: 314-273-8620
Division: Immunobiology
Titles
Adjunct Professor, ITMO University, St. Petersburg, Russia
Education
BSc in Computer Science (with honors), ITMO University, Saint Petersburg, Russia (2011)
MSc in Computer Science (with honors), ITMO University, Saint Petersburg, Russia (2013)
PhD in Bioinformatics, ITMO University, Saint Petersburg, Russia (2016)
Boards
Board title e.g. American Board of Pathology (Anatomic Pathology), 2014
Board title e.g. American Board of Pathology (Anatomic Pathology), 2014
Recognition
Skoltech Systems Biology Fellowship (2017-2019)
Research Interests
My general research interest lies in developing computational approaches for analysis of high-throughput data to help uncover novel biology. More specifically, there are three major directions my lab focuses on.
- Pathway analysis: we maintain and improve the FGSEA package (https://bioconductor.org/packages/fgsea) for pathway analysis, with recent developments targeted towards working with single-cell and spatial data.
- Network analysis: our lab works on a set of network analysis approaches with a focus on applications in the immunometabolism field (https://artyomovlab.wustl.edu/shiny/gatom/).
- Public data mining: we facilitate access to public transcriptomics data with gene expression analysis web-tools like Phantasus (https://alserglab.wustl.edu/phantasus).
Selected Publications
Analysis of Variants Induced by Combined Ex Vivo Irradiation and In Vivo Tumorigenesis Suggests a Role for the ZNF831 p.R1393Q Variant in Cutaneous Melanoma Development
Publication
CR1 variants contribute to FSGS susceptibility across multiple populations
Publication
GEODES: Geometric Descriptors for the Assessment of Global and Local Flexibility of Proteins during Molecular Dynamics Simulation
Publication
Complex trait susceptibilities and population diversity in a sample of 4,145 Russians
Publication
Assistant

Elizabeth Moore
Administrative Office Supervisor
Contact
- Email: melizabeth@wustl.edu
- Phone: 314-362-9103