Education
BS: Tehran University
MS: Tehran University
PhD: Weill Cornell Medicine
Recognition
NIH K99/R00 Awardee, NIA 2023
Jumpstart Career Development Award, Weill Cornell Medicine 2022-2023
Alzheimer’s Disease Research postdoctoral fellowship, BrightFocus Foundation 2020-2022
Research Interests
Our research investigates the role of the innate immune system in the pathogenesis of neurodegenerative diseases and the processes of brain aging, employing stem cell–based platforms and transgenic mouse models to study mechanisms of neuroimmune interactions in the brain.
Selected Publications
A single-cell, long-read, isoform-resolved case–control study of frontotemporal dementia reveals cell-type specific and broad splicing dysregulation in post-mortem human brain.
Alzheimer’s disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model.
Autophagy prevents microglial senescence.
Tau activation of microglial cGAS-IFN reduces MEF2C-mediated cognitive resilience.
Deriving Schwann cells from hPSCs enables disease modeling and drug discovery for diabetic peripheral neuropathy.
New insights and therapeutic opportunities for progranulin-deficient frontotemporal dementia.
Assistant
