
Richard J. Perrin, MD, PhD
Associate Professor, Pathology & Immunology
Contact
- Email: rperrin@wustl.edu
- Phone: 314-362-7426
Division: Neuropathology
Education
BS: Yale College, New Haven, CT (1992)
PhD: University of Illinois Urbana-Champaign, Champaign, IL (2001)
Medical Degree: University of Illinois – Chicago, Chicago, IL (2004)
Anatomic Pathology Residency: Washington University School of Medicine, St. Louis, MO (2006)
Neuropathology Fellowship: Washington University School of Medicine, St. Louis, MO (2008)
Boards
Neuropathology: Board Certified
Anatomic Pathology: Board Certified
Recognition
Robert Terry Award, American Association of Neuropathologists, 2013
Alpha Omega Alpha Medical Honor Society, 2003
Affiliations
Research Interests
Translational Human Neurodegenerative Disease Research to Advance Diagnostics, Understanding, and Treatments
I direct the Translational Human Neurodegenerative Disease Research (THuNDR) Laboratory, which serves as the Neuropathology Core of the Charles F. and Joann Knight Alzheimer Disease Research Center, the Dominantly Inherited Alzheimer Network, the Dominantly Inherited Alzheimer Network – Trials Unit, the Alzheimer Disease Neuroimaging Initiative, and the Washington University Movement Disorders Center. In this role, I perform neuropathologic evaluations of research participant brain donations and support collaborative translational research projects with investigators domestic and international, with a focus on understanding and developing biomarkers and treatments for neurodegenerative diseases.
Selected Publications
Integrative multiomics reveals common endotypes across PSEN1, PSEN2, and APP mutations in familial Alzheimer’s disease
Publication
Longitudinal analysis of a dominantly inherited Alzheimer disease mutation carrier protected from dementia
Publication
Safety and efficacy of long-term gantenerumab treatment in dominantly inherited Alzheimer's disease: an open-label extension of the phase 2/3 multicentre, randomised, double-blind, placebo-controlled platform DIAN-TU trial
Publication
Depressive Symptoms and Amyloid Pathology
Publication
Assistant
