Pavel Zakharov, PhD
Instructor, Pathology & Immunology
Contact
- Email: pzakharov@wustl.edu
Division: Immunobiology
Education
MS: Biophysics, Lomonosov Moscow State University, School of Physics, Moscow, Russia (2010)
PhD: Biophysics, Lomonosov Moscow State University, School of Physics, Moscow, Russia (2016)
Research Interests
Autoimmune diabetes
Systems biology
Bioinformatics
Selected Publications
CXCL16-dependent scavenging of oxidized lipids by islet macrophages promotes differentiation of pathogenic CD8<sup>+</sup> T cells in diabetic autoimmunity
Publication
Rapid unleashing of macrophage efferocytic capacity via transcriptional pause release
Publication
Cytocidal macrophages in symbiosis with CD4 and CD8 T cells cause acute diabetes following checkpoint blockade of PD-1 in NOD mice
Publication
Single-cell RNA sequencing of murine islets shows high cellular complexity at all stages of autoimmune diabetes
Publication