
Paul Buttars, DO
Assistant Professor, Pathology & Immunology
Contact
- Email: buttars@wustl.edu
- Phone: 314-273-7204
- Fax: 314-747-2662
Titles
Associate Director, Anatomical Pathology Residency Program
Education
DO – A.T. Still University, Kirksville College of Osteopathic Medicine
MS – A.T. Still University, Kirksville College of Osteopathic Medicine
BS – Weber State University
Boards
College of American Pathologists – Diplomat
Clinical Interests
I specialize in breast pathology with a focus on spindle cell lesions, prognostic markers across breast carcinoma subtypes, and the evaluation of lobular neoplasia and papillary lesions. My practice also includes general bone and soft tissue pathology, integrating morphologic, immunohistochemical, and molecular approaches to support accurate diagnosis and patient care.
Research Interests
My research focuses on the characterization of stromal components in both carcinomas and sarcomas, with an emphasis on their prognostic and predictive significance. I am also interested in expanding diagnostic capabilities through the application of polychromatic and uncommon histochemical stains. In addition, my work explores uncommon molecular alterations in high‑grade tumors, contributing to a deeper understanding of tumor biology and potential therapeutic targets. A parallel focus is the integration of digital pathology and artificial intelligence to enhance diagnostic precision, streamline workflows, and bridge morphologic, molecular, and computational approaches in translational pathology.
Related Links
Selected Publications
Alexiev BA, Vormittag-Nocito ER, Lorch J, Yeldandi A, Buttars PR, Jennings LJ. Uncommon molecular alterations in follicular-derived thyroid carcinoma: A single institution study. Pathol Res Pract. 2024 Jun;258:155355. doi: 10.1016/j.prp.2024.155355. Epub 2024 May 17. PMID: 38763089.
Ardor, Gokce Deniz, et al. “113 A Comparison Between HER2 Amplification by Fluorescent In-Situ Hybridization (FISH), Next Generation Sequencing (NGS), and Correlation with ERBB2 Mutations.” Laboratory Investigation 105.3 (2025).
Assistant

Charlsey Robinson
Administrative Assistant II
Contact
- Email: charlsey.robinson@wustl.edu
- Phone: 314-454-8462