Paul Allen, PhD

Emeritus Professor, Pathology and Immunology

  • BS, University of Michigan (1974)
  • MS, University of Michigan (1977)
  • PhD, University of Michigan (1981)

Research Interests

No active research programs

Editorial Responsibilities

2000 – present Associate Editor Immunity
1995 – 2003 Advisory Editor The Journal of Experimental Medicine
1991 – 1993 Section Editor The Journal of Immunology
1987 – 1991 Associate Editor The Journal of Immunology
1979 – 2000 Editor Immunity

Service to the Department

2003 – 2006  Director, Immunology Program

DBBS Graduate Program Affiliation

  • Immunology Program

Publications

Pub Med Search

Shih FF, Racz J, Allen PM. Differential MHC class II presentation of a pathogenic autoantigen during health and disease. J Immunol 176:3438-48, 2006 Abstract
Norian LA, Allen PM. No intrinsic deficiencies in CD8+ T cell-mediated anti-tumor immunity with aging. J Immunol 173:835-844, 2004 Abstract
Wipke BT, Wang Z, Nagengast W, Reichert DE, Allen PM. Staging the initiation of autoantibody induced arthritis: a critical role for immune complexes. J Immunol 172:7694-7702, 2004 Abstract
Hanson HL, Kang SS, Norian LA, Matsui K, O’Mara LA, Allen PM. CD4-directed peptide vaccination augments an antitumor response, but efficacy is limited by the number of CD8+ T cell precursors.. J Immunol 172:4215-4224, 2004 Abstract
Shih FF, Mandik-Nayak L, Wipke BT, Allen PM. Massive thymic deletion results in systemic autoimmunity through elimination of CD4+CD25+ T regulatory cells. J Exp Med 199:323-335, 2004 Abstract
Mandik-Nayak L, Wipke BT, Shih FF, Unanue ER, Allen PM. Despite ubiquitous autoantigen expression, arthritogenic autoantibody response initiates in the local lymph node. Proc Natl Acad Sci USA 99:14368-14373, 2002 Abstract
Hailman E, Burack WR, Shaw AS, Dustin ML, Allen PM. Immature CD4+CD8+ thymocytes form a multifocal immunological synapse with sustained tyrosine phosphorylation. Immunity 16:839-848, 2002 Abstract
Basu D, Horvath S, O’Mara L, Donermeyer D, Allen PM. Two MHC surface amino acid differences distinguish foreign peptide recognition from autoantigen specificity. J Immunol 166:4005-4011, 2001 Abstract
Kersh GJ. Miley MJ, Nelson CA, Grakoui A, Horvath S, Donermeyer DL, Kappler J, Allen PM, and Fremont. Structural and functional consequences of altering a peptide MHC anchor residue. J Immunol 164:5788-5796, 2001 Abstract
Basu D, Horvath S, Matsumoto I, Fremont DH, Allen PM. Molecular basis for recognition of an arthritic peptide and a foreign epitope on distinct MHC molecules by a single TCR. J Immunol 164:5788-5796, 2000 Abstract
Grakoui A, Bromley SK, Sumen C, Davis MM, Shaw AS, Allen PM, Dustin ML. The immunological synapse: A molecular machine controlling T cell activation. Science 285:221-227, 1999 Abstract
Williams CB, Engle DL, Kersh GJ, White JM, Allen PM. A kinetic threshold between negative and positive selection based on the longevity of the T cell receptor-ligand complex. J Exp Med 189:1531-1544, 1999 Abstract
Daniel C, Horvath S, Allen PM. A basis for alloreactivity: MHC helical residues broaden peptide recognition by the TCR. Immunity 8:543-552, 1998 Abstract
Kersh GJ, Kersh EN, Fremont DH, Allen PM. High- and low-potency ligands with similar affinities for the TCR: The importance of kinetics in TCR signaling. Immunity 9:817-826, 1998 Abstract
Kersh EN, Shaw AS, Allen PM. Fidelity of T cell activation through multistep T cell receptor zeta phosphorylation. Science 281:572-575, 1998 Abstract