
Nicholas Borcherding, MD, PhD
Assistant Professor, Pathology and Immunology
Contact
- Email: borcherding.n@wustl.edu
Division: Laboratory and Genomic Medicine
Titles
Fellow, Histocompatibility and Immunogenetics
Education
BS, Nutritional Sciences: Iowa State University (2012)
MS, Pathology: University of Iowa (2014)
PhD, Cancer Biology: University of Iowa (2020)
MD: University of Iowa (2020)
Clinical Pathology Residency: Washington University School of Medicine (2023)
Boards
Clinical Pathology
Board title e.g. American Board of Pathology (Anatomic Pathology), 2014
Recognition
Emerging Generation Award, The American Society for Clinical Investigation (2022)
Paul E. Strandjord Young Investigator Award, Academy of Laboratory Physicians and Scientists (2022)
Williams L. Roberts Young Investigator Award with Distinction, Academy of Laboratory Physicians and Scientists (2021)
Special Achievement in Pathology, Iowa Pathology Society (2020)
Hancher-Finkbine Medallion, University of Iowa (2019)
Related Links
Research Interests
The adaptive immune system is a central node in the molecular pathogenesis across all diseases. Encoded within our genome is the ability to respond to the vast array of pathogens and, if improperly regulated, ourselves. My research has focused on developing computational approaches to distilling and deciphering adaptive immune receptor sequences and tracking immune cell interaction through intracellular mitochondria transfer.
Selected Publications
Myelin-reactive CD8<sup>+</sup> T cells influence conventional dendritic cell subsets towards a mature and regulatory phenotype in experimental autoimmune encephalomyelitis
Publication
Somatic CRISPR tumorigenesis and multiomic analysis reveal a pentose phosphate pathway disruption vulnerability in MPNSTs
Publication
Antigen and eplet coverage by representative solid-phase immunoassays for anti-HLA antibody screen
Publication
scRepertoire 2: Enhanced and efficient toolkit for single-cell immune profiling
Publication
Assistant
