Lulu Sun, MD, PhD

Lulu Sun, MD, PhD

Assistant Professor, Pathology & Immunology

Division

  • Anatomic & Molecular Pathology

Education

  • BS: McGill University, Montreal, Quebec, Canada
  • MD/PhD: Washington University School of Medicine in St. Louis
  • Residency: Anatomic Pathology, Washington University School of Medicine in St. Louis
  • Molecular Genetic Pathology Fellowship: Washington University School of Medicine in St. Louis
  • Gynecologic and Breast Pathology Fellowship: Washington University School of Medicine in St. Louis

Board Certifications

  • Anatomic Pathology
  • Molecular Genetic Pathology

Subspecialization

  • Breast Pathology
  • Gynecologic Pathology
  • Molecular Pathology

Research Interests

My clinical interests are in gynecologic, breast, and molecular pathology. My research interests are in the genetic pathways that lead to gynecologic malignancy and applying sequencing technologies to personalized cancer profiling and treatment.

Selected Publications

Sun L, Dehner C, Kenney J, McNulty SM, Zhu X, Pfeifer JD, Maluf HM, Chrisinger JSA. Clinicopathologic and molecular features of six cases of phosphaturic mesenchymal tumor. Virchows Arch. 2021;478(4):757-765. PMID: 33151412
Sun L, Wu A, Bean GR, Hagemann IS, Lin CY. Molecular Testing in Breast Cancer: Current Status and Future Directions. J Mol Diagn. 2021. PMID: 34454106
Sun L, McNulty SN, Evenson MJ, Zhu X, Robinson J, Mann PR, Duncavage EJ, Pfeifer JD. Clinical Implications of a Targeted RNA Sequencing Panel in the Detection of Gene Fusions in Solid Tumors. J Mol Diagn. 2021. PMID: 34562614
Sun L, Schroeder MC, Hagemann IS, Pfeifer JD, Schwarz JK, Grigsby PW, Markovina S, Lin AJ. Expression of Potential Biomarker Targets by Immunohistochemistry in Cervical Carcinomas. International Journal of Gynecological Pathology. 2022. PMID: 35067601.
Sun L, Petrone JS, McNulty SN, Evenson MJ, Zhu X, Robinson J, Chernock RD, Duncavage EJ, Pfeifer JD. Comparison of Gene Fusion Detection Methods in Salivary Gland Tumors. Hum Pathol. 2022 Feb 17;123:1019. PMID: 35183572
Almajnooni A, Laharwani H, Wu A, Young AL, Lin CY, Sun L. Predictive and prognostic biomarker testing in invasive breast cancer. Diagnostic Histopathology. Epub. 2023
Sun L, Dehner C, Kenney J, McNulty SM, Zhu X, Pfeifer JD, Maluf HM, Chrisinger JSA. Clinicopathologic and molecular features of six cases of phosphaturic mesenchymal tumor. Virchows Arch. 2021 Apr;478(4):757-765. doi: 10.1007/s00428-020-02963-w. Epub 2020 Nov 5. PubMed PMID: 33151412.
Sun L, Marsh JN, Matlock MK, Chen L, Gaut JP, Brunt EM, Swamidass SJ, Liu TC. Deep learning quantification of percent steatosis in donor liver biopsy frozen sections. EBioMedicine. 2020 Oct;60:103029. doi: 10.1016/j.ebiom.2020.103029. Epub 2020 Sep 24. PubMed PMID: 32980688; PubMed Central PMCID: PMC7522765.
Sun L, Pfeifer JD. Pitfalls in molecular diagnostics. Semin Diagn Pathol. 2019 Sep;36(5):342-354. doi: 10.1053/j.semdp.2019.06.002. Epub 2019 Jun 4. Review. PubMed PMID: 31182318.
Sun L, Cliften PF, Duncavage EJ, Lewis JS Jr, Chernock RD. UV Signature Mutations Reclassify Salivary High-grade Neuroendocrine Carcinomas as Occult Metastatic Cutaneous Merkel Cell Carcinomas. Am J Surg Pathol. 2019 May;43(5):682-687. doi: 10.1097/PAS.0000000000001231. PubMed PMID: 30986802.
Sun L, Zhang L, Krigman HR, Hagemann IS. p16 Immunohistochemistry Is Not Always Required For Accurate Diagnosis of Grade 2 Squamous Intraepithelial Lesions. J Low Genit Tract Dis. 2018 Apr;22(2):104-109. doi: 10.1097/LGT.0000000000000370. PubMed PMID: 29570565; PubMed Central PMCID: PMC5868428.
Steed AL, Christophi GP, Kaiko GE, Sun L, Goodwin VM, Jain U, Esaulova E, Artyomov MN, Morales DJ, Holtzman MJ, Boon ACM, Lenschow DJ, Stappenbeck TS. The microbial metabolite desaminotyrosine protects from influenza through type I interferon. Science. 2017 Aug 4;357(6350):498-502. doi: 10.1126/science.aam5336. PubMed PMID: 28774928; PubMed Central PMCID: PMC5753406.
Sun L, Miyoshi H, Origanti S, Nice TJ, Barger AC, Manieri NA, Fogel LA, French AR, Piwnica-Worms D, Piwnica-Worms H, Virgin HW, Lenschow DJ, Stappenbeck TS. Type I interferons link viral infection to enhanced epithelial turnover and repair. Cell Host Microbe. 2015 Jan 14;17(1):85-97. doi: 10.1016/j.chom.2014.11.004. Epub 2014 Dec 4. PubMed PMID: 25482432; PubMed Central PMCID: PMC4297260.

Assistant
Charlsey Robison
314-454-8462
charlsey.robinson@wustl.edu
BJCIH Room 3422