Laura Campisi, PhD

Division

• Immunobiology

Additional Titles

• Assistant Professor, Center for Brain Immunology and Glia

Education

• Ph.D. in Immunology, University of Nice-Sophia Antipolis  
• Master in Genetic, Development and Immunity, University of Nice-Sophia Antipolis 
• B.S. in Biochemistry, School of Life Sciences, University of Nice-Sophia Antipolis 

Recognition

• Post-doctoral Recognition Award, Office of Postdoctoral Affairs, Icahn School of Medicine at Mount Sinai, New York, USA (2013)
• Arthritis Foundation Post-doctoral Award, USA (2011-2014)
• FRM (Fondation pour la recherché medicale) Fellowship, France (2008-2009)
• French Minister of Research and Education (MENRT) Fellowship, France (2005-2008)

Research Interests

The overall goal of my research is to understand how T-cell responses are regulated in homeostatic conditions and how perturbations (genetic, environmental, parasitic) alter their effect. By studying T cell responses using genetic models we can learn not only about a specific disorder, but also discover unknown factors that regulate the immune system and reveal molecular and cellular mechanisms for T cell therapy in multiple settings: neurodegeneration, autoimmunity, cancer, infection. 

Selected Publications

Campisi, L., Chizari, S., Ho, J.S.Y. et al. Clonally expanded CD8 T cells characterize amyotrophic lateral sclerosis-4. Nature 606, 945–952 (2022). https://doi.org/10.1038/s41586-022-04844-5

Rialdi A, Campisi L, Zhao N, Lagda AC, Pietzsch C, Ho JSY, Martinez-Gil L, Fenouil R, Chen X, Edwards M, Metreveli G, Jordan S, Peralta Z, Munoz-Fontela C, Bouvier N, Merad M, Jin J, Weirauch M, Heinz S, Benner C, van Bakel H, Basler C, García-Sastre A, Bukreyev A, Marazzi I. Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation. Science. 2016 May 27;352(6289):aad7993. doi: 10.1126/science.aad7993

Campisi, L., Barbet, G., Ding, Y. et al. Apoptosis in response to microbial infection induces autoreactive TH17 cells. Nat Immunol 17, 1084–1092 (2016). https://doi.org/10.1038/ni.3512

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Assistant
Elizabeth Moore
melizabeth@wustl.edu
314-362-9103