Kyunghee Choi, PhD

Professor, Pathology & Immunology

Divisions

Immunobiology

Division: Immunobiology

Education

BS, Seoul National University, Korea

MS, Seoul National University, Korea

PhD, University of Illinois at Chicago, Chicago, IL

DBBS Affiliations

Developmental, Regenerative and Stem Cell Biology Program

Immunology Program

Cancer Biology Program

Molecular Cell Biology Program

Research Interests

Hematopoietic and endothelial development 
We study hematopoietic and endothelial cell development. We focus on the molecular mechanisms that control mesoderm commitment to the hematopoietic and endothelial cell lineages. Particularly, we investigate the interaction among VEGF, Flk1, and an ETS transcription factor ETV2, as these three factors play a deterministic role in the formation of hematopoietic and endothelial cells. We have expertise in hematopoietic, vascular, and stem cell biology and stem cell applications.

Hematopoiesis and angiogenesis in cancer
We study hematopoiesis and angiogenesis in the context of cancer. Particularly, we investigate mechanisms that lead to hematopoietic stem and progenitor changes in the tumor.  We also investigate mechanisms by which tumor angiogenesis affects tumor immunity. We hope to apply the knowledge obtained from these studies to ultimately modulate tumor immunity and tumor growth.

Selected Publications

WashU Medicine Profile

Assistant

Randi Lee

Administrative Professional

Lab Phone: 314-362-9045
Office Location: BJC-IH Building, Room 8215