
Jacqueline Payton, MD, PhD
Associate Professor, Pathology & Immunology
Contact
- Email: jpayton@wustl.edu
Titles
Co-Director, Pathology Physician Scientist Training Program
Associate Medical Director, Molecular Diagnostics Laboratory
Education
BS: Bradley University, Peoria, IL (1996)
PhD: University of Illinois Urbana-Champaign, Urbana, IL (2002)
MD with Honors: University of Illinois Chicago College of Medicine (2004)
Clinical Pathology Residency: Washington University and Barnes-Jewish Hospital, St. Louis, MO (2008)
Boards
Diplomate, American Board of Pathology, Clinical Pathology, 2008
Recognition
Ellis Benson Award, Academy of Clinical Laboratory Physicians and Scientists (ACLPS), 2017
Distinguished Investigator Award, Washington University School of Medicine, 2016
College of American Pathologists Foundation Research Scholar Award, 2008
Paul E. Strandjord Young Investigator Award, Academy of Clinical Laboratory Physicians & Scientists, 2007
American Medical Women’s Association Janet M. Glasgow Memorial Citation, University of Illinois at Chicago College of Medicine at Urbana-Champaign, 2004
Scholar Award from P.E.O. Sisterhood, a philanthropic educational organization, 2003
Otto Saphir Award for Excellence in Pathology, University of Illinois at Chicago College of Medicine, 2003
Summa Cum Laude, Bradley University, Peoria, IL, 1996
DBBS Affiliations
Biomedical Informatics and Data Science
Cancer Biology
Molecular Genetics and Genomics
Molecular Microbiology and Microbial Pathogenesis
Research Interests
Lymphoma, epigenetics, gene regulation, host-pathogen interface
The overarching goal of my research program is to elucidate regulatory mechanisms in the immune system, with a focus on infection and malignancy. The foundation of our work is the discovery of novel pathogenic gene regulatory processes, which we experimentally test using molecular, cellular, and animal models to dissect underlying mechanisms and identify potential therapeutic strategies. Throughout these studies, we apply cutting edge multi-omics approaches and develop innovative bioinformatic tools to reveal novel gene regulatory processes1-4. As a molecular pathologist, I develop and optimize clinical molecular assays for precision medicine approaches to diagnosis and disease monitoring. My translational and clinical research thus incorporates diverse approaches from molecular pathology, informatics, immunology, and systems biology.
Selected Publications
Molecular basis for human respiratory syncytial virus transcriptional regulator NS1 interactions with MED25
Publication
Evaluation of Long-Read Genome Sequencing for Genomic Profiling of Myeloid Cancers
Publication
ACLY promotes NK cell effector function by regulating glycolysis and histone acetylation
Publication
Ebola virus VP35 NNLNS motif modulates viral RNA synthesis and MIB2-mediated signaling
Publication
Assistant

Jennifer Schwierjohn
Administrative Professional
Contact
- Email: j.schwierjohn@wustl.edu
- Phone: 314-273-1743