Education
B.Sc. Biotechnology, University of Pune, India
M.Sc. Biotechnology, University of Pune, India
Ph.D. Biology, Indian Institute of Science Education and Research Bhopal, India
Research Interests
My research focuses on understanding how T cells regulate neuroinflammation and neurodegeneration in the context of ALS. I am interested in applying omics-based approaches, including single-cell and spatial transcriptomics, to dissect immune cell states and their interactions with the central nervous system. My broader interests span innate and adaptive immunity, functional genomics, and host-immune interactions.
- Neuroinflammation
- Single-cell transcriptomics
- Functional genomics
- CRISPR-based screens
Selected Publications
The neonatal Fc receptor is a cellular receptor for human astrovirus
IFN-λ derived from nonsusceptible enterocytes acts on tuft cells to limit persistent norovirus
Murine astrovirus tropism for goblet cells and enterocytes facilitates an IFN-λ response in vivo and in enteroid cultures
Viral complementation of immunodeficiency confers protection against enteric pathogens via interferon-λ
Assistant