Hao-Wei Chang, PhD

Instructor, Pathology and Immunology

Divisions

Immunobiology

Education

PhD: Washington University in St. Louis

MS: National Yang Ming University, Taiwan

BS: National Chung Hsing University, Taiwan

Research Interests

The quest to understand what we should eat to remain healthy has been a long-standing search, dating back to the dawn of civilization. Today, despite numerous advancements, we still face significant challenges, such as childhood undernutrition, obesity, and related diseases. My long-term research interest is to explore the intricate relationship between nutrition science, microbiology, and immunology.

Selected Publications

Effects of microbiota-directed therapeutic foods in gnotobiotic mice, gnotobiotic piglets, and undernourished children.

Publication

Prevotella copri and microbiota members mediate the beneficial effects of a therapeutic food for malnutrition

Publication

Gut microbiome contributions to altered metabolism in a pig model of undernutrition

Publication

A sparse covarying unit that describes healthy and impaired human gut microbiota development

Publication

Bioactive glycans in a microbiome-directed food for children with malnutrition

Publication

TREM2 deficiency reprograms intestinal macrophages and microbiota to enhance anti–PD-1 tumor immunotherapy

Publication

Deficiency of IL-22-binding protein enhances the ability of the gut microbiota to protect against
enteric pathogens

Publication