Bridgit Crews, PhD

Bridgit Crews, PhD

Associate Professor, Pathology & Immunology

Division

  • Laboratory & Genomic Medicine

Additional Titles

  • Medical Director of Mass Spectrometry and Clinical Toxicology

Education

  • BA, Chemistry: University of California Davis (2001)
  • PhD, Chemistry: University of California Santa Barbara (2007)
  • Postdoctoral Research Fellow: The Scripps Center for Mass Spectrometry and Metabolomics, La Jolla, California (2008)
  • Fellowship, Clinical Chemistry: Washington University School of Medicine, St. Louis, Missouri (2013)

Board Certifications

Diplomate, American Board of Clinical Chemistry: Chemistry (2013), Toxicology (2016)

Clinical Interests

  • Clinical Mass Spectrometry Applications
  • Therapeutic Drug Monitoring
  • Urine Drug Testing
  • Endocrinology

Research Interests

My research focuses on the development and clinical application of mass spectrometry (MS) technologies, including liquid chromatography tandem MS, high-resolution MS, and inductively coupled plasma MS to detect and quantify drugs, steroid hormones, metals, and other clinically relevant biomarkers that may be used to diagnose or monitor disease.  

Selected Publications

Commentary. Crews BO. Clin Chem. 2018 Sep;64(9):1294-1295. doi: 10.1373/clinchem.2017.286161.PMID: 30154198 
A Patient in Need of a Red Cell Exchange? Perez-Alvarez I, Crews BO, Woo JS, Rezk S, Tran MH. J Appl Lab Med. 2021 Jul 7;6(4):1057-1061. doi: 10.1093/jalm/jfaa159.PMID: 33241416 
Advances in detection of hemoglobinopathies. Greene DN, Vaughn CP, Crews BO, Agarwal AM. Clin Chim Acta. 2015 Jan 15;439:50-7. doi: 10.1016/j.cca.2014.10.006. Epub 2014 Oct 12.
A Striking Contrast. Mkhikian H, Crews BO. Clin Chem. 2018 Aug;64(8):1265-1266. doi: 10.1373/clinchem.2017.284224.PMID: 30054304 
Age- and Sex-Associated Variations in the Sensitivity of Serological Tests Among Individuals Infected With SARS-CoV-2. Vashisht R, Patel A, Crews BO, Garner OB, Dahm L, Wilson C, Butte AJ.JAMA Netw Open. 2021 Feb 1;4(2):e210337. doi: 10.1001/jamanetworkopen.2021.0337.PMID: 33576815
Data-driven quality assurance to prevent erroneous test results. Crews BO, Drees JC, Greene DN.Crit Rev Clin Lab Sci. 2019 Nov 2:1-15. doi: 10.1080/10408363.2019.1678567. Online ahead of print.PMID: 31680585
The Lines That Held Us: Assessing Racial and Socioeconomic Disparities in SARS-CoV-2 Testing. Hsiao CJ, Patel AGM, Fasanya HO, Stoffel MR, Beal SG, Winston-McPherson GN, Campbell ST, Cotten SW, Crews BO, Kuan K, Lapedis CJ, Mathias PC, Peck Palmer OM, Greene DN.J Appl Lab Med. 2021 Sep 1;6(5):1143-1154. doi: 10.1093/jalm/jfab059.PMID: 34240171
Infection prevention strategies are highly protective in COVID-19 units while main risks to healthcare professionals come from coworkers and the community. Gohil SK, Quan KA, Madey KM, King-Adelsohn S, Tjoa T, Tifrea D, Crews BO, Monuki ES, Khan S, Schubl SD, Bittencourt CE, Detweiler N, Chang W, Willis L, Khusbu U, Saturno A, Rezk SA, Figueroa C, Jain A, Assis R, Felgner P, Edwards R, Hsieh L, Forthal D, Wilson WC, Stamos MJ, Huang SS.Antimicrob Resist Infect Control. 2021 Nov 22;10(1):163. doi: 10.1186/s13756-021-01031-5.PMID: 34809702 
Recent trends in designer drug abuse. Crews BO, Petrie MS.Clin Chem. 2015 Jul;61(7):1000-1. doi: 10.1373/clinchem.2015.240416.PMID: 26322357 
Evaluation of Commercially Available High-Throughput SARS-CoV-2 Serologic Assays for Serosurveillance and Related Applications. Stone M, Grebe E, Sulaeman H, Di Germanio C, Dave H, Kelly K, Biggerstaff BJ, Crews BO, Tran N, Jerome KR, Denny TN, Hogema B, Destree M, Jones JM, Thornburg N, Simmons G, Krajden M, Kleinman S, Dumont LJ, Busch MP.Emerg Infect Dis. 2022 Mar;28(3):672-683. doi: 10.3201/eid2803.211885.PMID: 35202525

Assistant
Susan Keen
keen@wustl.edu
314-273-8136