Division
- Immunobiology
Lab Affiliation
Education
- BS: Pharmacy, College of Pharmacy, Seoul National University, Korea
- MS: Molecular Pharmacology, College of Pharmacy, Seoul National University, Korea
- PhD: Molecular Pharmacology, College of Pharmacy, Seoul National University, Korea
- Postdoctoral: Molecular Pharmacology, College of Pharmacy, Dongguk University-Seoul, Korea
- Postdoctoral: Pathology-Immunobiology, Washington University School of Medicine in St. Louis
Research Statement
My research focuses on lipoprotein trafficking, organ-to-organ communications, and inflammatory diseases regarding liver and intestinal injury. Specifically, I have studied the HDL trafficking and excretion which is a crucial element in cholesterol homeostasis and its tissue of origin in regulating intestinal adaptation and metabolic responses.
Research Interests
- Pathology
- Metabolism
Publications
| Kim A, Koo JH, Jin X, Kim W, Park SY, Park S, Rhee EP, Choi CS, Kim SG. (2021). Ablation of USP21 in skeletal muscle promotes oxidative fiber phenotype, inhibiting obesity and type 2 diabetes. J Cachexia Sarcopenia Muscle. 12(6),1669-1689. |
| Kim A*, Koo JH*, Lee JM, Joo MS, Kim TH, Kim H, Jun DW, Kim SG. (2022). NRF2-mediated SIRT3 induction protects hepatocytes from ER stress-induced liver injury. FASEB JOURNAL. 36(3), e22170. (*co-first author) |
| Wu HM, Kim TH, Kim A, Koo JH, Joo MS, Kim SG. (2019). Liver X Receptor α-Induced Cannabinoid Receptor 2 Inhibits Ubiquitin-Specific Peptidase 4 Through miR-27b, Protecting Hepatocytes From TGF-β. Hepatol Commun. 3(10):1373-1387 |
| Han CY, Rho HS, Kim A, Kim TH, Jang K, Jun DW, Kim JW, Kim B, Kim SG. (2018). FXR Inhibits Endoplasmic Reticulum Stress-Induced NLRP3 Inflammasome in Hepatocytes and Ameliorates Liver Injury. Cell Rep. 24(11), 2985-2999. |
| Kim A*, Lee CG*, Lee DY, Li H, Jeon R, Ryu JH, Kim SG. Enhanced antioxidant effect of prenylated polyphenols as Fyn inhibitor. Free Radic Biol Med. 2012;53(5):1198-208. (*co-first author) |