Aydan Szeto, PhD

Assistant Professor, Pathology and Immunology

Divisions

Immunobiology

Szeto Lab

Office Location: BJC Institute of Health, 8th Floor, Office 8822

Education

PhD in Immunology, University of Cambridge

BA in Natural Sciences (Biological), University of Cambridge

Recognition

MRC Career Development Fellow (2020-2025)

Croucher Cambridge International Scholar (2016-2020)

St. John’s College Lister Scholar (2013-2016)

Research Interests

We investigate the biology of type 2 immune cells with a particular focus on fundamental discovery and molecular regulation. We employ in vitro high-throughput genetic screens and in vivo models of immunity to discover and understand the contribution of novel factors to tissue and organismal homeostasis, immune diseases (autoimmunity and allergy) and cell therapy (neurodegeneration and cancer).

Selected Publications

Mef2d potentiates type-2 immune responses and allergic lung inflammation (Science 2024)

Publication

An αvβ3 integrin checkpoint is critical for efficient TH2 cell cytokine polarization and potentiation of antigen-specific immunity (Nature Immunology 2023)

Publication

Neuroprotective protein ADNP-dependent histone remodeling complex promotes T helper 2 immune cell differentiation (Immunity 2023)

Publication

Molecular mechanisms regulating T helper 2 cell differentiation and function (Current Opinion in Immunology 2024)

Publication

Assistant

Randi Lee

Administrative Professional