Anjum Hassan, MD

Anjum Hassan, MD

Professor, Pathology and Immunology

Division

  • Anatomic & Molecular Pathology

Clinical Interests

  • Hematopathology

Research Interests

My past research involved work on small lymphocytic leukemia, a project that eventually involved setting up the system for direct sequencing of immunoglobulin genes from paraffin sections. Another focus of my previous research involved studying the pathogenesis of Multiple Myeloma, a pilot study to optimize PCR detection of ras mutations in archival material in the Department of Pathology and Immunology and correlating that with t(4;14) and t(11;14) in established myeloma cases. For additional information on my papers, please refer to my portfolio. My current research focuses mainly of translational projects with a focus on B- cell Non-Hodgkin lymphoma and research related to reviews and updates of previously authored book chapters.

Service to the University

2021- Present Inaugural faculty advisor, Washington University School of Medicine
MSA (muslim student association)
2008- PresentMember, Committee of Admissions 
Washington University School of Medicine, St. Louis, MO
2016-2020Member, Selection Committee on University Scholars in Medicine Program; Washington University School of Medicine, St. Louis, MO
2009-2020Member, Hematopathology Program Evaluation Committee, Department of Pathology and Immunology
2016-PresentMember Hematopathology Fellowship Clinical Competency Committee, Department of Pathology and Immunology
2018- PresentMember AP/CP Pathology Residency Clinical Competency Committee, Department of Pathology and Immunology

Department Affiliations

2005-2010Assistant Director, FISH Laboratory, Anatomic Pathology, Washington University School of Medicine
2013-2015Associate Program Director, WASHU/BJH/SLCH, Hematopathology Fellowship
2015-2019Director, WASHU/BHJ/SLCH Hematopathology  Fellowship
2010-2023Director, FISH Laboratory, Cytogenomics and Pathology Services, Washington University School of Medicine
2006-2014Assistant Professor, Division of Anatomic and Molecular Pathology, Washington University School of Medicine
2015-2023Associate Professor, AMP Division , Washington University School of Medicine
2024- Professor, Division of Anatomic and Molecular Pathology, Washington University School of Medicine

Selected Publications

Klein  J.L, Nguyen T.T., Bien-Willner G, Chen L, Foyil K.V,Bartlett  N, Duncavage  E.J, Hassan A, Frater J.L, Kreisel F. CD163 is a more useful immunohistochemical stain than CD68 in predicting outcome of patients with classical Hodgkin lymphoma. Am J Clin Pathol. 2014 Mar;141(3):381-387
Gru A.A, Hussaini M, Nguyen T, Frater J.LKreisel FHassan AHigh prevalence of 1p36 microdeletions in B-cell non-Hodgkin lymphomas associated with PAX7 loss. 
2013         Int J Lab Hematol 35(4):e1-5.
Hussaini MO, Klein J, Xiao J, Frater J.L, Kreisel F, Hassan A. Richter Syndrome: an Unusual Report of Concurrent Small Lymphocytic Lymphoma, Hodgkin Lymphoma, and Anaplastic Plasmacytoma. J applied hematol 2014; 5 (1):23-26.
Xu X, Hassan A.  Extranodal marginal zone lymphoma arising in a patient with chronic myelogenous leukemia on long-term tyrosine kinase inhibitors. Leuk Lymphoma. 2014 Mar; 55(3):715-717.
Foster AE, Nguyen TT, Al-Hammadi N, Frater JL, Hassan A, Kreisel F. Clinical presentation, progression, and outcome of patients with clonal B-cell counts of less than 5 × 10(9)/l, 5 to 10 × 10(9)/l, and more than 10 × 10(9)/l and chronic lymphocytic leukemia immunophenotype. Am J Clin Pathol. 2015 Jan; 143(1):70-77.
Hussaini MO, Kreisel FH, Hassan A, Nguyen TT, Frater JL.  CD4-positive diffuse large B-cell lymphoma: A variant with aggressive clinical potential. World J Methodol 2016; 6(3): 181-186.
Miller CA, Tricarico C, Uy G L , Lee Y , Hassan A, O’Laughlin M, Schmidt H, Tian L, Duncavage E J., Griffith M, Griffith O L, Welch J S, Wartman L D. A case of acute myeloid leukemia with promyelocytic features characterized by expression of a novel RARG-CPSF6 fusion. Blood Adv. 2018 Jun 12; 2(11):1295-1299.
Hussain MO, Yeung C, Zhu X, Mirza AS, Pfeifer J , Hassan A. PRDM1 expression levels in Marginal Zone Lymphoma and Lymphoplasmacytic Lymphoma. Int J Clin Exp Pathol 2017; 10(8):8610-8618.
Persaud SP, Hassan A, Hassan A, Hassan T. Severe Cytomegalovirus Gastritis during Natalizumab-Mediated Immunosuppression. ACG Case Rep J. 2017 Mar 15; 4:e43.
Aqil B, Triska G, Frater J, Hassan A, Ruzinova MB, Cashen A, Reese Y, Kreisel F. Immunophenotypic Variations in Mantle Cell Lymphoma and Their Impact on Clinical Behavior and Outcome. 2018 Oct; 142(10):1268-1274. doi: 10.5858/arpa.2017-0368-OA. Epub 2018 Jun 5. PMID: 29869903
Brestoff JR, Toland A, Afaneh K, Press B, Kresiel F, Westervelt P, Hassan A. Bone marrow biopsy needle type affects core biopsy length and quality. Am J Clin Pathol. 2019 Jan 7; 151(2):185-193. doi: 10.1093/ajcp/aqy126. PMID: 30307478
Poondru S, Joseph A, Harding JC, Mehta-Shah, N, Green P, Hassan A, Rauch DA , Ratner L. Adult T- cell Leukemia-Lymphoma presenting concurrently with myopathy.  Case Rep Oncol 2022;15: 918-926
Barnell EK, Skidmore ZL, Newcomer KF, Chavez M, Campbell KM, Cotto KC, Spies NC, Ruzinova MB, Wang T, Abro B, Kreisel F, Parikh BA, Duncavage EJ, Frater JL, Lee YS, Hassan A, King JA, Kohnen DR, Fiala MA, Welch JS, Uy GL, Vij K, Vij R, Griffith M, Griffith OL, Wartman LD. Distinct clonal identities of B-ALLs arising after lenolidomide therapy for multiple myeloma. Blood Adv. 2023 Jan 24;7(2):236-245. doi: 10.1182/bloodadvances.2022007496. PMID: 36251745; PMCID: PMC9860439.

Book/Book Chapters

Brooj Abro, John D. Pfiefer, Louis P. Dehner, Anjum Hassan
Ed. Washington Manual of Hematopathology. Lippincott Williams & Wilkins, Philadelphia, PA, 2023. In press.
Amna Qureshi, Anjum Hassan, Anne Chen. The Bone marrow. Chapter 23. Pediatric Pathology, Fifth Edition, edited by  Mai (Mike) He, Louis P. Dehner, and Aliya N. Husain. Lippincott Williams & Wilkins, Philadelphia, PA, 2024, in press.
Chen Yang, Anjum Hassan, Lymph Nodes Chapter 43 in Washington Manual of Pathology. Lippincott Williams & Wilkins, Philadelphia, PA, 2018.
Brooj Abro, Chen Yang, Anjum Hassan. Spleen. Chapter 45 in Washington Manual of Pathology. Lippincott Williams & Wilkins, Philadelphia, PA, 2018.
Lily Zhang, Yi-Shan Lee, Anjum Hassan. Florescence-in-situ Hybridization. Chapter 59 in Washington Manual of Pathology. Lippincott Williams & Wilkins, Philadelphia, PA, 2018.

Assistant
Jill Guess
314-362-0108
jill.guess@wustl.edu
BJCIH Room 3422