
Aayushi Uberoi, PhD
Assistant Professor, Pathology & Immunology
Contact
- Email: uberoi@wustl.edu
- Phone: Office 314-273-8682 // Lab 314-273-8683
Division: Laboratory and Genomic Medicine
Office Location: 7749 Clinical Science Research Building (CSRB)
Lab Location: 7746 Clinical Science Research Building (CSRB)
Education
B.Tech (Hons): SRM School of Engineering, SRM University, Chennai, India (2011)
Ph.D. (Cancer Biology): University of Wisconsin-Madison, U.S.A. (2017)
Recognition
Society of Investigative Dermatology Type II Innovator Award (2024)
Thermo Fisher Scientific-Applied Biosciences 40th Anniversary:40 Innovative scientists worldwide (2023)
National Institutes of Health K99/R00: Pathway to Independence Award (2022-Present)
Career Development Award, Dermatology Foundation (2021)
Awesome Games Done Quick Fellow of Prevent Cancer Foundation (2020-2021)
Young Investigator Award, Wound Healing Society (2020)
Joshua Neimark Research Award, American Association for Advancement of Science (2016)
Dr. Hargobind Khorana Award by the Indo-US Science and Technology Forum (2010)
Research fellow, Indian Academy of Sciences, Govt. of India (2009)
Research fellow, Jawaharlal Nehru Centre for Advanced Scientific Research (2008)
Research Interests
The skin provides the first line of defense for all vertebrates. An effective skin barrier is essential to life and protects the underlying organs from dehydration, inflammation, environmental exposure, and infections. The skin houses the skin microbiome which is unique and distinct in its composition and plays a critical role in educating the skin barrier defenses. My lab’s research program aims to identify molecular and biochemical mechanisms that mediate microbial symbiosis with host skin. In this context we are interested in understanding how microbiome impacts skin barrier repair and regeneration in state of homeostasis and disease (e.g., chronic wounds, atopic dermatitis and cancer).
Selected Publications
Commensal-derived tryptophan metabolites fortify the skin barrier: Insights from a 50-species gnotobiotic model of human skin microbiome
Publication
Deficiency in Ever2 does not increase susceptibility of mice to pathogenesis by the mouse papillomavirus, MmuPV1
Publication
Microbiome-Based Diagnostics for Disease: Where Are We Now and Where Are We Headed?
Publication
Alcaligenes faecalis corrects aberrant matrix metalloproteinase expression to promote reepithelialization of diabetic wounds
Publication
Assistant
