Anjum Hassan, MD
Associate Professor, Pathology & Immunology
- Phone:
- Email: ahassan22@nospam.wustl.edu
Division
- Anatomic & Molecular Pathology
Additional Titles
- Medical Director FFPE FISH in Anatomic and Molecular Pathology
Clinical Interests
- Hematopathology
Research Interests
My past research involved work on small lymphocytic leukemia, a project that eventually involved setting up the system for direct sequencing of immunoglobulin genes from paraffin sections. Another focus of my previous research involved studying the pathogenesis of Multiple Myeloma, a pilot study to optimize PCR detection of ras mutations in archival material in the Department of Pathology and Immunology and correlating that with t(4;14) and t(11;14) in established myeloma cases. For additional information on my papers, please refer to my portfolio. My current research focuses mainly of translational projects with a focus on B- cell Non-Hodgkin lymphoma and research related to reviews and updates of previously authored book chapters.
Service to the University
| 2015 – 2019 | Fellowship Director, Section of Hematopathology |
| 2014 – Present | Coarse Director, WUSM hematopathology electives |
| 2010 – Present | Medical Director FFPE FISH in Cytogenomics and Molecular Pathology |
| 2008 – Present | Member, Committee on Admissions, Washington Univ. School of Medicine |
| 2006 – 2009 | Assistant Director, Fluorescent in-situ Hybridization Lab in Anatomic Pathology |
| 2005 – 2008 | Second-year Adrenal pathology course |
| 2005 – Present | Second-year medical student Hematopathology Lab curriculum |
Selected Publications
| Xiao J , Nguyen T, Frater J.L, Kreisel F, Hassan A. Evolution of Mantle Cell Lymphoma “in situ†Contributing to Immune Thrombocytopenia.. Leukemia and lymphoma., 2014 |
| Klein J.L, Nguyen T.T., Bien-Willner G, Chen L, Foyil K.V,Bartlett N, Duncavage E.J, Hassan A, Frater J.L, Kreisel F. CD163 is a more useful immunohistochemical stain than CD68 in predicting outcome of patients with classical Hodgkin lymphoma.. Am J Clin Pathol, 2014 |
| Gru AA, Kreisel F, Duncavage E, Nguyen TT, Hassan A, Frater J. Acute EBV infection masquerading as “in-situ follicular lymphoma”: A pitfall in the differential diagnosis of this entity. Diagn Pathol, 2013 |
| Xiandong X, Hassan A. Hairy cell leukemia misdiagnosed as Large cell lymphoma: Immunohistochemical studies aiding differential diagnosis.. J applied hematol, 2013 |
| Hussaini MO, Klein J, Xiao J, Frater J.L, Kreisel F, Hassan A. Richter Syndrome: an Unusual Report of Concurrent Small Lymphocytic Lymphoma, Hodgkin Lymphoma, and Anaplastic Plasmacytoma.. J applied hematol, 2013 |
| Xiandong X, Hassan A. Extranodal marginal zone lymphoma arising in a patient with chronic myelogenous leukemia on long term decitabine therapy. Leukemia and lymphoma, 2013 |
| Gru A.A, Hussaini M, Nguyen T, Frater J.L, Kreisel F, Hassan A. High prevalence of 1p36 microdeletions in B-cell non-Hodgkin lymphomas associated with PAX7 loss. Int J Lab Hematol, 2013 |
| Pittman M, Treese S, Chen L, Frater J.L, Nguyen TT, Hassan A. Utility of flow cytometry of cerebrospinal fluid as a screening tool in the diagnosis of central nervous system lymphoma. Arch Pathol Lab Med, 2012 |
| Wang T, Klein JL, Woodard PK, Hassan A, Joseph SM, Ewald GA, Uy GL. Plasmacytoma-like Posttransplant Lymphoproliferative Disease Occurring in a Cardiac Allograft: A Case Report and Review of Literature.. J Clin Oncol, 2012 |
| Deetz C.O, Scott M.G., Ladenson J.H., Seyoum M., Hassan A, Kreisel F.H, Nguyen T.T, Frater J.L.Use of a United States-based laboratory as a hematopathology reference center for a developing country: logistics and results. Int J Lab Hematol, 2012 |
| Warrick J, Luo J, Robirds D, Branson J, Frater J.L, Kreisel F, Hassan A, Nguyen T.T.Gastrointestinal lymphomas in a North American population: clinicopathologic features from one major Central-Midwestern United states tertiary care medical center. Diagn Pathol, 2012 |
| Yeung C.C, Mills JC, Hassan A, Kreisel F.H, Nguyen T.T, Frater J.L. A novel marker of plasmacytic differentiation. Appl Immunohistochem Mol Morphol, 2012 |
| Hussaini M, Kreisel F , Hassan A. Impact of proliferative indices and tumor suppressor genes on treatment response in marginal zone lymphomas. comp clin pathol, 2012 |
| Welch J S, Klco J M, Gao F, Cashen A. F, Uy G. L, Stockerl-Goldstein K. E, Abboud C.M , Westervelt P, DiPersio J.F , Hassan A, Vij R. . Combination Decitabine, Arsenic trioxide and Ascorbic Acid for the Treatment of Myelodysplastic syndrome and Acute Myeloid Leukemia:a phase I study. Am J Hematol, 2011 |
| Amador-Ortiz C, Hurley M.Y, Ghahramani G.K, Frisch S, Klco J.M, Lind A.C, Nguyen T.T, Hassan A, Kreisel F.H, Frater J.L. Use of classic and novel immunohistochemical markers in the diagnosis of cutaneous myeloid sarcoma. J Cutan Path, 2011 |
| Klco J.M, Welch J.S, Nguyen T.T, Hurley M.Y, Kreisel F, Hassan A, Lind A.C, Frater J.L. State of art in myeloid sarcoma. Int J Lab Hematol, 2011 |
| Kreisel F, Kulkarni S, Kerns R. T, Hassan A , Deshmukh H, Nagarajan R , Frater J. L, Cashen A.High-resolution array comparative genomic hybridization (aCGH) identifies copy number alterations in diffuse large B-cell lymphoma that predict response to immuno-chemotherapy. Cancer Genet, 2011 |
| Amador-Ortiz C, L. Chen, A. Hassan, J.L. Frater, R. Burack, T.T. Nguyen, F. Kreisel. Combined core needle biopsy and fine needle aspiration with ancillary Studies correlate highly with traditional techniques in the diagnosis of nodal-based lymphoma. Am J Clin Pathol., 2011 |
| Klco J.M,Kulkarni S, Kreisel F.H, Nguyen T.T, Hassan A, Frater J.L. Immunohistochemical analysis of monocytic leukemias: utility of CD14 and Krüppel-like factor 4, a novel monocytic marker. Am J Clin Pathol, 2011 |
| Nanua S, Bartlett N, Hassan A, Robirds D, Brawson J, Frater J. L, Nguyen T.T, Kreisel. Composite diffuse large B-cell lymphoma and precursor B lymphoblastic lymphoma presenting as a double-hit lymphoma with MYC and BCL2 translocation.. J clin pathol, 2011 |
| Yeung C CS, Powers MLE, Kreisel F.H, Frater J. L, Zehnbauer B. A, Burack R, Hassan A.Relevance of Somatic Hypermutation and Interphase Cytogenetics in Lymphomatous Presentation of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL). Int J Surg Pathol, 2011 |
| Hassan A. Minimal residual disease testing in acute leukemia. J app hematol, 2011 |
| Ansstas G, Mosley J.C, Bryant G, Hassan A, Amador-Ortiz C, Procknow E, Vij R. Efficacy and Tolerability of PTK787/ZK 222584 in a Phase II Study of Post-Transplant Maintenance Therapy in Patients with Multiple Myeloma Following High-Dose Chemotherapy and Autologous Stem Cell Transplant. Leukemia and Lymphoma, 2010 |
| Klco J.M, Vij R, Kreisel F.H, Hassan A, Frater J.L. Molecular pathology of myeloproliferative neoplasms. Am J Clin Pathol, 2010 |
| Kreisel F.H, Frater J, Hassan A, El-Mofty S.K. Cystic lymphoid hyperplasia of the parotid gland in HIV-positive and HIV-negative patients. Quantitative Immunopathology, 2010 |
| Cai S F., Cao X, Hassan A, Fehniger TA., and Ley TJ. Granzyme B is not required for regulatory T cell mediated suppression of graft-versus-host Disease. Blood, 2010 |
| Klco J. M, Geng B, Brunt E. M, Hassan A, Nguyen T. D, Kreisel F. H, Lisker-Melman M, Frater J. L.Bone marrow biopsy in patients with hepatitis C virus infection: Spectrum of findings and diagnostic utility. Am J Hematol, 2010 |
| Krishmurthy S, Hassan A, Frater J. L, Paessler M. E, Kreisel F. Pathologic and clinical features of Hodgkin lymphoma-like post transplant lymphoproliferative disease. Int J Surg Pathol, 2010 |
| O’Neal J, Molitoris A, Gao F, Hassan A, Monahan R, Barrios S, Weilbaecher K, Vij R, Tomasson M. Neurobeachin (NBEA) is a target of recurrent interstitial deletions at 13q13 in patients with MGUS and multiple myeloma. Experimental Hematology, 2009 |
| Klco JM, Kreisel FH, Zehnbauer BA, Kulkarni S, Hassan A, Frater JL. The spectrum of adult B-lymphoid leukemias with BCR-ABL: molecular diagnostic, cytogenetic, and clinical laboratory perspectives.. Am J Hematol, 2008 |
| Powers M LE, Watson BW, Frater JL, Kreisel F, Hassan A. Peripheral Eosinophilia Camouflaging Anaplastic Large Cell Lymphoma. Int J. Surg. Pathol, 2008 |
| Zhao, XF, Hassan A, Perry A, Ning Y, Stass SA, Dehner LP. B-cell lymphomas with atypical morphology and c-myc rearrangements. Int J clin exp pathol 1(1): 65-74,2008 ., 2008 |
| Hassan A, Kreisel F, Lewis J, Gardner L, El-Mofty S.. Plasmablastic lymphoma of head and neck: report of two new cases and correlation with c-myc and IgVH gene mutation status. Head and Neck pathology, Oct 2007, available on line. DOI 10.1007/s12105-007-00060-5., 2007 |
| Kaleem Z, Hassan A. Pathologic Quiz Case: Multiple lytic bone lesions in an 85-year-old man.. Arch Pathol Lab Med 129:e148-150, 2005 Abstract |
| Hassan A, Yerian LM, Kuan SF, Xiao SY, Hart J, Wang HL. Immunohistochemical evaluation of adenomatous polyposis coli, beta-catenin, c-Myc, cyclin D1, p53, and retinoblastoma protein expression in syndromic and sporadic fundic gland polyps.. Hum Pathol 35:328-334, 2004 Abstract |
| Kaleem Z, Hassan A, Pathan MH, White G. Flow Cytometric Evaluation of Posttransplant B-Cell Lymphoproliferative Disorders.. Arch Pathol Lab Med 128:181-186, 2004 Abstract |
| Hassan A, Bennet A, Bhalla S, Ylagan LR, Mutch D, Dehner LP. Paraganglioma of the vagina: Ultrastructural and immunohistochemical study.. Int J Gynecol Pathol, 22:404-406, 2003 Abstract |
| Liapis H, Hassan A. Idiopathic light chain deposition disease without clinical evidence of Multiple Myeloma. Int Urol Nephrol 35:579-580, 595-596, 2003 Abstract |
| Coopersmith CA, Lowell JA, Hassan A, Howard TK. Hepatocellular carcinoma in a patient with focal nodular hyperplasia.. Arch Pathol Lab Med 128:181-186, 2002 |
Assistant
Jill Guess
314-362-0108
jill.guess@wustl.edu
BJCIH Room 3422