Author: Gabrielle

WashU Medicine researchers have described how mRNA cancer vaccines engage the immune system, through an unconventional pathway involving two subsets of immune cells called dendritic cells.

Sarah Ackerman, PhD, an assistant professor of pathology & immunology at WashU Medicine, has been named a winner of the Maximizing Innovation in Neuroscience Discovery (MIND) Prize.

The Department of Pathology and Immunology at Washington University School of Medicine is proud to announce that Vahid Azimi, MD and Stephen Roper, PhD were part of a multidisciplinary team that was recently named a Univants of Healthcare Excellence Team of Distinction by Abbott.  The team sought to reduce the barrier in prenatal care for black […]

Two innovative pilot projects led by researchers at Washington University School of Medicine in St. Louis have received funding from the Chan-Zuckerberg Initiative to address critical challenges in the fields of neurodegeneration and neuroscience. The initiative has awarded a total of $12.8 million to more than 60 pilot projects nationwide. Each project receives $200,000 over […]

Physicians treating patients with early-stage lung cancer face a conundrum: choosing potentially helpful yet toxic therapies such as chemotherapy, radiation or immunotherapy to knock out the cancer and lessen the risk of it spreading to the brain, or waiting to see if lung surgery alone proves sufficient. When up to 70% of such patients do […]

A team including scientists from Yale School of Medicine and Scott Handley, PhD, Professor of Pathology and Immunology at Washington University School of Medicine, have received $575,000 from PolyBio Research Foundation to fund long COVID research. The grant will support the team’s efforts to define mechanisms by which the SARS-CoV-2 virus can persist for long […]

Three graduate students affiliated with labs in the Department of Pathology and Immunology have been named Spencer T. and Ann W. Olin Medical Science Fellows. Lucas Adams, an MD/PhD student in the Division of Biology and Biomedical Sciences (DBBS) Immunology program who is completing his thesis work in the labs of Dr. Daved Fremont and […]

There lies a paradox in sleep. Its apparent tranquility juxtaposes with the brain’s bustling activity. The night is still, but the brain is far from dormant. During sleep, brain cells produce bursts of electrical pulses that cumulate into rhythmic waves – a sign of heightened brain cell function. But why is the brain active when we […]

A genetic test that identifies cancer mutations in solid tumors and that was developed by researchers at Washington University School of Medicine in St. Louis has been approved for reimbursement by the Centers for Medicare & Medicaid Services (CMS). The test, known as GatewaySeq, identifies mutations that can be targeted with available drugs, helping advance […]

Jeffrey I. Gordon, MD, of Washington University School of Medicine in St. Louis, has received the 2024 Mechthild Esser Nemmers Prize in Medical Science from Northwestern University. Gordon was selected for the prize by a jury of distinguished U.S. scientists for transforming the understanding of human health and how it is shaped by the gut […]

Scientists at Washington University School of Medicine in St. Louis have found passageways that connect the brain to vessels that carry fluid waste out of and away from the brain. The newly discovered anatomical structures, found in mice and people, are like tiny gates, allowing waste to leave the brain and enter lymphatic vessels, where […]

Cold and flu season is upon us, and thanks to a new report developed by a team in the Department of Pathology and Immunology, individuals in the BJC hospital system and School of Medicine can better track pathogens causing common illnesses.  A collaborative team including members of the BJH Molecular Infectious Disease Laboratory and P&I […]

The Department of Pathology and Immunology at Washington University School of Medicine is pleased to announce 18 physicians have been named Castle Connolly Top Doctors in 2024. “The recognition of these physicians is a testament to the high quality of our entire faculty, whose work benefits patients across our entire region,” said Richard J. Cote, […]

Millions of children in under-resourced parts of the world suffer from malnutrition and, consequently, stunted growth. Protein-based therapeutic foods designed to restore health are lifesavers for many, but a significant number of malnourished children do not respond to available therapies. But now, researchers at Washington University School of Medicine in St. Louis have found that […]

An atomic-level investigation of how Eastern equine encephalitis virus binds to a key receptor and gets inside of cells also has enabled the discovery of a decoy molecule that protects against the potentially deadly brain infection, in mice. The study, from researchers at Washington University School of Medicine in St. Louis, is published Jan. 3 […]

Rocky Giwa, a graduate student in the Brestoff Lab, and Wentong Jia, PhD, a postdoctoral researcher in the Brestoff Lab, have been awarded fellowships from the American Heart Association (AHA). The fellowships recognize the outstanding work Rocky and Dr. Jia contribute to the Brestoff Lab and their potential to become leaders in scientific research. “I’m […]

Three trainees in the Department of Pathology and Immunology have been awarded educational grants from the Association of Pathology Chairs (APC). Patricia Hernandez, MD, Resident in Clinical Pathology; Zita Hubler, MD, PhD, Resident in Clinical Pathology and the Physician Scientist Training Program; and Yanchun Lin, PhD, Clinical Chemistry Fellow, have all received funding for their […]

A clinical trial reported in 2021 and conducted by a team of researchers from Washington University School of Medicine in St. Louis and the International Centre for Diarrhoeal Disease Research in Dhaka, Bangladesh, showed that a newly designed therapeutic food aimed at repairing malnourished children’s underdeveloped gut microbiomes was superior to a widely used standard […]

Alzheimer’s disease has plagued one large Colombian family for generations, striking down half of its members in the prime of life. But one member of that family evaded what had seemed would be fate: Despite inheriting the genetic defect that caused her relatives to develop dementia in their 40s, she stayed cognitively healthy into her […]

Researchers and clinicians at Washington University in St. Louis have found a way to improve the standard of care diagnostic accuracy of potentially cancerous lesions in the ovaries and adnexal regions, or the fallopian tubes, by incorporating functional biomarkers with photoacoustic imaging, a technique that illuminates tissue with near-infrared light at specific wavelengths that are […]

Robert D. Schreiber, PhD, an internationally recognized scientist in cancer immunology at Washington University School of Medicine in St. Louis, has been named the 2024 Senior Scientist Winner of the Innovators in Science Award in Cancer Immunology. The award is given by the New York Academy of Sciences and sponsored by Takeda Pharmaceuticals. Schreiber, the […]

Clarivate, an analytics company, has named more than 50 Washington University in St. Louis researchers to its Highly Cited Researchers 2023 list including several members of the Department of Pathology and Immunology. Researchers from Pathology and Immunology highlighted in Clarivate’s list include: Clarivate’s Highly Cited Researchers list, which was established in 2001, identifies scientists and […]

Researchers at Washington University School of Medicine in St. Louis have found an innovative way to block infection by a variety of alphaviruses, a group of mosquito-borne viruses that can cause joint and brain infections in people. The study, led by Michael S. Diamond, MD, PhD, the Herbert S. Gasser Professor of Medicine, and Daved […]

 Sarah D. Ackerman, Gabor Egervari, MD, PhD and Tao Xie, all of Washington University School of Medicine in St. Louis, have been named 2023 Young Investigator grantees by the Brain & Behavior Research Foundation. This year’s funding will support 150 promising early-career scientists across the field of neuropsychiatry with innovative ideas in mental health research. The two-year grant is expected […]