Chieh-Yu Lin, MD, PhD

Chieh-Yu Lin, MD, PhD

Associate Professor, Pathology & Immunology
Section Head, Autopsy

 

Division

  • Anatomic & Molecular Pathology

Education

  • MD: National Taiwan University, Taipei, Taiwan (2009)
  • PhD: Stanford University, Stanford, CA (2014)
  • Residency, Anatomic Pathology : Stanford University, Stanford, CA (2017)
  • Fellowship, Breast Pathology: Stanford University, Stanford, CA (2017)
  • Fellowship, Molecular Genetic Pathology : Stanford University, Stanford, CA (2018)

Board Certifications

  • Anatomic Pathology, American Board of Pathology, 2017
  • Molecular Genetic Pathology, American Board of Pathology, 2018

Recognition

  • Alpha Omega Alpha Honor Medical Society
  • Department of Pathology & Immunology Faculty Teacher of the Year (2019-2020

Professional Society

  • Chair, Education Committee, Society for Cardiovascular Pathology (SCVP)
  • Member, Education Committee, The United States and Canadian Academy of Pathology (USCAP) 
  • Member, Membership Committe, International Society for Heart and Lung Transplantation (ISHLT)

Clinical Interests

  • Cardiothoracic Pathology
  • Molecular Genetic Pathology
  • Breast Pathology

Research Interests

My main research interest is to understand the pathogenesis of myocarditis and heart transplant rejection, and to develop clinically-applicable tools with a multi-disciplinary approach to provide better diagnostic, prognostic and predicative value.  

Selected Publications

Wein AN, Liu J, Lin CY*. Evolution of pathological findings in surveillance biopsies of lung transplant recipients infected with SARS-CoV-2. Transplant Infectious Disease, 2022 Jun;24(3):e13823
Moreno JD, Verma AK, Kopecky BJ, Dehner C, Kostelecky N, Vader JM, Lin CY*, Schilling JD, Angiotensin II type 1 receptor antibody mediated rejection following orthotopic heart transplant: a single center experience. Transplantation. 2022 Feb 1;106(2):373-380
Liu J, Ma P, Lai L, Villanueva A, Koenig A, Bean GR, Bowles DE, Glass C, Watson M, Lavine KJ, Lin CY* (2022). Transcriptional and Immune Landscape of Cardiac Sarcoidosis. Circulation research, 131(8), 654–669
Verma A, Lavine K, Lin CY*, Myocarditis after Covid-19 mRNA Vaccination. New England Journal of Medicine. 2021 Sep 30;385(14):1332-1334. 
Bailey A, Dmytrenko O, Greenberg L, Bredemeyer A, Ma P, Liu J, Penna V, Winkler ES, Sviben S, Brooks E, Nair AP, Heck KA, Rali AS, Simpson L, Saririan M, Hobohm D, Stump WT, Fitzpatrick JA, Xie X, Shi PY, Hinson JT, GI WT, Schmidt C, Leuschner F, Lin CY*, Diamond MS, Greenberg MJ, Lavine KJ. SARS-CoV-2 Infects Human Engineered Heart Tissues and Models COVID-19 Myocarditis. JACC: Basic to Translational Science, in press
English S, Sastriques S, Detering L, Sultan D, Luehmann H, Arif B, Heo G, Zhang X, Laforest R, Zheng J, Lin CY, Gropler R, and Liu Y. CCR2 positron emission tomography for the assessment of abdominal aortic aneurym inflammation and rupture prediction. Circulation: Cardiovascular Imaging. 2020 Mar;13(3):e009889. doi: 10.1161/CIRCIMAGING.119.009889
Adamo L, Rocha-Resende C, Lin CY, Evans S, Williams JW, Dun H, Li W, Mpoy C, Andhey P, Rogers BE, Lavine K, Kreisel D, Artyomov MN, Randolph GJ, Mann D. Myocardial B cells are a subset of circulating lymphocytes with delayed transit through the heart. JCI Insight. 2020 Feb 13;5(3).
Hoffmann JC, Lin CY, Bhattacharyya S, Weinberg OK, Chisholm KM, Bayerl M, Cascio M, Venkataraman G, Allison K, Troxell M, Chang CC, Bagg A, George TI, O’Malley D, Ohgami RS. Rosai-Dorfman Disease of the Breast with Variable IgG4+ Plasma Cells: A Diagnostic Mimicker of Other Malignant and Reactive Entities. American Journal of Surgical Pathology. 2019 Dec;43(12):1653-1660
Lin CY*, Saleem A, Stehr H, Zehnder JL, Pinsky BA, Kunder CA. Molecular profiling of clear cell adenocarcinoma of the urinary tract. Virchows Archiv. 2019 Dec;475(6):727-734
Lin CY, Vennam S, Purington N, Lin E, Varma S, Han S, Desa M, Seto T, Wang NJ, Stehr H, Troxell ML, Kurian KW, West RB. Genomic landscape of ductal carcinoma in situ and association with progression. Breast Cancer Research and Treatment. 2019 Nov;178(2):307-316 
Lin CY, Mooney K, Choy W, Yang SR, Barry-Holson K, Horst K, Wapnir I, Allison H. Will Oncotype Dx DCIS Testing Guide Therapy? A Single Institution Correlation of Oncotype Dx DCIS Results with Histopathologic Findings and Clinical Management Decisions. Modern Pathology, 2018 Apr;31(4):562-568.
Yang SR, Lin CY, Stehr H, Long SR, Kong CS, Berry G, Zehnder JL, Kunder CA. Comprehensive genomic profiling of malignant effusions in patients with metastatic lung adenocarcinoma. Journal of Molecular Diagnostics. 2018 Mar;20(2):184-194.
Zhang BM, Aleshin A, Lin CY, Ford J, Zehnder JL, Suarez C. IDH2 mutation in a patient with metastatic colon cancer. New England Journal of Medicine. 2017; 376:1991-1992.
Lin CY, Carneal EE, Lichtensztajn DY, Gomez SL, Clarke CA, Jensen KC, Kurian AW, Allison KH. Regional variability in percent of breast cancers reported as positive for HER2 in California: implications of patient demographics on laboratory benchmarks. American Journal of Clinical Pathology. 2017 Sep 1;148(3):199-207.

Assistant:
Keli Morris
314-362-1329
kelibeckett@wustl.edu
BJCIH Room 3422