Division
- Anatomic & Molecular Pathology
Education
- BS: McGill University, Montreal, Quebec, Canada
- MD/PhD: Washington University School of Medicine in St. Louis
- Residency: Anatomic Pathology, Washington University School of Medicine in St. Louis
- Molecular Genetic Pathology Fellowship: Washington University School of Medicine in St. Louis
- Gynecologic and Breast Pathology Fellowship: Washington University School of Medicine in St. Louis
Board Certifications
- Anatomic Pathology
- Molecular Genetic Pathology
Subspecialization
- Breast Pathology
- Gynecologic Pathology
- Molecular Pathology
Research Interests
My clinical interests are in gynecologic, breast, and molecular pathology. My research interests are in the genetic pathways that lead to gynecologic malignancy and applying sequencing technologies to personalized cancer profiling and treatment.
Selected Publications
| Compadre A, Van Biljon L, Valentine M, Llop-Guevara A, Graham E, Fashemi B, Herencia-Ropero A, Kotnik EN, Cooper I, Harrington SP, Kuroki L, McCourt C, Hagemann A, Thaker P, Mutch DG, Powell M, Sun L, Mosammaparast N, Serra V, Zhao P, Lomonosova E, Khabele D, Mullen M. RAD51 foci as a biomarker predictive of platinum chemotherapy response in ovarian cancer. Clinical Cancer Research. 2023; 29 (13):2466-2479. PMID 37097615. |
| Chen L, Shi V, Wang S, Freeman R, Ruiz F, Jayachandra K, Zhang J, Cosper P, Sun L, Luke CJ, Spina C, Grigsby PW, Schwarz JK, Markovina S. SCCA/SERPINB3 suppresses antitumor immunity and blunts therapy-induced T cell responses via STAT-dependent chemokine production. Journal of Clinical Investigation. 2023; 133(15):e163841. PMID 37279067. |
| Chapagain U, Krigman HR, Hagemann IS, Weiss MC, Sun L. COL1A1::PDGFB fusion-associated uterine sarcoma and response to imatinib: A case report. Gynecologic Oncology Reports. 2023; 49. |
| Almajnooni A, Laharwani H, Wu A, Young AL, Lin CY, Sun L. Predictive and prognostic biomarker testing in invasive breast cancer. Diagnostic Histopathology. Epub. 2023 |
| Sun L, Schroeder MC, Hagemann IS, Pfeifer JD, Schwarz JK, Grigsby PW, Markovina S, Lin AJ. Expression of Potential Biomarker Targets by Immunohistochemistry in Cervical Carcinomas. International Journal of Gynecological Pathology. 2022. PMID: 35067601. |
| Sun L, Petrone JS, McNulty SN, Evenson MJ, Zhu X, Robinson J, Chernock RD, Duncavage EJ, Pfeifer JD. Comparison of Gene Fusion Detection Methods in Salivary Gland Tumors. Hum Pathol. 2022 Feb 17;123:1019. PMID: 35183572 |
| Sun L, Dehner C, Kenney J, McNulty SM, Zhu X, Pfeifer JD, Maluf HM, Chrisinger JSA. Clinicopathologic and molecular features of six cases of phosphaturic mesenchymal tumor. Virchows Arch. 2021;478(4):757-765. PMID: 33151412 |
| Sun L, Wu A, Bean GR, Hagemann IS, Lin CY. Molecular Testing in Breast Cancer: Current Status and Future Directions. J Mol Diagn. 2021. PMID: 34454106 |
| Sun L, McNulty SN, Evenson MJ, Zhu X, Robinson J, Mann PR, Duncavage EJ, Pfeifer JD. Clinical Implications of a Targeted RNA Sequencing Panel in the Detection of Gene Fusions in Solid Tumors. J Mol Diagn. 2021. PMID: 34562614 |
| Sun L, Dehner C, Kenney J, McNulty SM, Zhu X, Pfeifer JD, Maluf HM, Chrisinger JSA. Clinicopathologic and molecular features of six cases of phosphaturic mesenchymal tumor. Virchows Arch. 2021 Apr;478(4):757-765. doi: 10.1007/s00428-020-02963-w. Epub 2020 Nov 5. PubMed PMID: 33151412. |
| Sun L, Marsh JN, Matlock MK, Chen L, Gaut JP, Brunt EM, Swamidass SJ, Liu TC. Deep learning quantification of percent steatosis in donor liver biopsy frozen sections. EBioMedicine. 2020 Oct;60:103029. doi: 10.1016/j.ebiom.2020.103029. Epub 2020 Sep 24. PubMed PMID: 32980688; PubMed Central PMCID: PMC7522765. |
| Sun L, Pfeifer JD. Pitfalls in molecular diagnostics. Semin Diagn Pathol. 2019 Sep;36(5):342-354. doi: 10.1053/j.semdp.2019.06.002. Epub 2019 Jun 4. Review. PubMed PMID: 31182318. |
| Sun L, Cliften PF, Duncavage EJ, Lewis JS Jr, Chernock RD. UV Signature Mutations Reclassify Salivary High-grade Neuroendocrine Carcinomas as Occult Metastatic Cutaneous Merkel Cell Carcinomas. Am J Surg Pathol. 2019 May;43(5):682-687. doi: 10.1097/PAS.0000000000001231. PubMed PMID: 30986802. |
| Sun L, Zhang L, Krigman HR, Hagemann IS. p16 Immunohistochemistry Is Not Always Required For Accurate Diagnosis of Grade 2 Squamous Intraepithelial Lesions. J Low Genit Tract Dis. 2018 Apr;22(2):104-109. doi: 10.1097/LGT.0000000000000370. PubMed PMID: 29570565; PubMed Central PMCID: PMC5868428. |
| Steed AL, Christophi GP, Kaiko GE, Sun L, Goodwin VM, Jain U, Esaulova E, Artyomov MN, Morales DJ, Holtzman MJ, Boon ACM, Lenschow DJ, Stappenbeck TS. The microbial metabolite desaminotyrosine protects from influenza through type I interferon. Science. 2017 Aug 4;357(6350):498-502. doi: 10.1126/science.aam5336. PubMed PMID: 28774928; PubMed Central PMCID: PMC5753406. |
| Sun L, Miyoshi H, Origanti S, Nice TJ, Barger AC, Manieri NA, Fogel LA, French AR, Piwnica-Worms D, Piwnica-Worms H, Virgin HW, Lenschow DJ, Stappenbeck TS. Type I interferons link viral infection to enhanced epithelial turnover and repair. Cell Host Microbe. 2015 Jan 14;17(1):85-97. doi: 10.1016/j.chom.2014.11.004. Epub 2014 Dec 4. PubMed PMID: 25482432; PubMed Central PMCID: PMC4297260. |
Assistant
Charlsey Robison
314-454-8462
charlsey.robinson@wustl.edu
BJCIH Room 3422