Cheryl Lichti, PhD
Associate Professor, Pathology & Immunology
Contact
- Email: clichti@wustl.edu
- Phone: 314-273-1736
Division: Immunobiology
Education
BA, Chemistry, Hendrix College, Conway, AR
PhD, Organic Chemistry, Duke University, Durham, NC
Postdoctoral Research Associate, Organic Chemistry, University of Colorado, Boulder, CO
Recognition
2021 Outstanding Paper of the Year Award, Department of Pathology and Immunology
Research Interests
My work is focused in the unbiased sequence characterization of major histocompatibility complex (MHC)-bound ligands by mass spectrometry, with a specific focus on post-translationally modified neoantigens. My work is collaborative in nature and currently involves studies of type 1 diabetes, tumor immunology, and neurodegenerative diseases.
Selected Publications
A microenvironment-driven HLA-II-associated insulin neoantigen elicits persistent memory T cell activation in diabetes
Publication
Massively parallel immunopeptidome by DNA sequencing provides insights into cancer antigen presentation
Publication
Itaconate modulates immune responses via inhibition of peroxiredoxin 5
Publication
Endogenous self-peptides guard immune privilege of the central nervous system
Publication