The Department of Pathology & Immunology maintains a number of core facilities that support the research, diagnostic and training missions of the department and the school. Together, they are full-service centers that provide state-of-the-art technology in support of basic and translational research, as well as diagnostic activities of the Medical Campus.
Some of these facilities provide services to outside customers on a contractual basis. However, all are generally available to Washington University School of Medicine faculty.
- AMP Core Labs: The Anatomic and Molecular Pathology Core Labs (AMP Labs) is a CAP/CLIA certified resource that provides clinical and research services in anatomic pathology.
- Cytogenetics Core: The Cytogenetics Core provides a comprehensive menu of cytogenetic tests for human and mouse tissues. The core also offers consultation and support for clinical trials/studies for which CAP/CLIA certification is needed.
- Digital Imaging Center: The Digital Imaging Center is a joint resource of the Department of Pathology & Immunology and Barnes Jewish Hospital. The center specializes in digital imaging for clinical, teaching and research applications.
- Electron Microscopy Facility: The Electron Microscopy Facility (CAP/CLIA certified) provides a variety of electron microscopy services for clinical and research use, including: Tissue processing and embedding and routine transmission electron microscopy for cell culture and tissue specimens.
- Flow Cytometry Core: The Flow Cytometry Core provides investigators with instrumentation and support for cell sorting as well as assistance with experimental design, acquisition and analysis of flow cytometry data.
- Hybridoma Center: With over 35 years of experience, the Hybridoma Center assists investigators in the generation of custom monoclonal antibody-producing B cell hybridomas.
- Immunomonitoring Lab: The Immunomonitoring Lab offers a comprehensive suite of state-of-the-art instrumentation and expert support in the areas of multiplex imaging, mass cytometry, immunoassays, and tetramer development. Researchers from both within Washington University as well as external academic and industry institutions are welcomed.
- Transgenic, Knockout and Micro-Injection Core: The Transgenic, Knockout and Micro-Injection Core offers a wide array of mouse embryo manipulation techniques, including cryopreservation of mouse lines, cryopreservation/storage of mouse sperm, embryo rederivation, embryos thawing and IVF.
A variety of relevant core facilities are available elsewhere in the institution. A list of all core facilities for the university can be found in the Office of the Vice Chancellor of Research.