Molecular Genetic Pathology Fellowship

The Molecular Genetic Pathology fellowship program is a joint undertaking between the Divisions of Anatomic and Molecular Pathology, Laboratory and Genomic Medicine, and Neuropathology.

The fellowship is a one year position accredited by the ACGME, and is designed to meet the needs of trainees interested in a careers focused on the application of molecular genetic techniques to translational science and the clinical laboratory.

For applicants interested in basic science careers, additional research years may be available through the physician scientist-training program (PSTP) within the department.  During training fellows will learn how to design and validate molecular assays, interpret molecular testing results (including NGS based sequencing), and to best use the results of molecular testing to improve patient care.  The overall fellowship training is flexible and allows trainees to spend additional time focused on key sub-specialty areas of interest within molecular diagnostics.

History

Fellowship approved by Accreditation Council for Graduate Medical Education (ACGME) to begin July 1, 2008. The fellowship has graduated 19 fellows to date.

Curriculum

The Washington University School of Medicine and Barnes-Jewish Hospital provides the clinical material for the program. The fellowship includes laboratory rotations through the clinical Molecular Diagnostic Laboratory, Microbiology Laboratory, HLA Laboratory, and FISH Laboratory of Barnes-Jewish Hospital; the Cytogenetics Laboratory, Microarray Laboratory of the Department of Pathology; Genomics and Pathology Services at Washington University (GPS @ WU); and the Bioinformatics section of the Department of Pathology. The fellowship also includes clinical rotations through the general pediatric genetics clinic and the general adult genetics clinic (as well as elective rotations through the neurogenetics, Down syndrome, or Beckwith-Wiedemann clinics). The fellowship provides a strong emphasis on the application of high throughput technologies to molecular oncology, and fellows will spend considerable time in our state of the art next generation sequencing laboratory (GPS @ WU) learning all aspects of the process including specimen intake, panel design, data analysis, and case sign-out.  Fellows will be active in the Washington University genomics tumor board held in conjunction with the McDonnell Genome Institute.  Fellows will also participate in regular didactic teaching sessions with faculty, and contribute to departmental conferences and journal clubs.  Fellows are encouraged to present research findings at national meetings.

The fellowship maintains 3 fully funded, ACGME-accredited one-year positions, is among the largest MGP fellowship training programs in the country, and was the first to offer clinical NGS based training.  Trainees will interact directly with ordering physicians, geneticists, bioinformaticians,  research faculty providing full breadth of training.  The program is especially focused on the application of a full range of sequencing based assays to improve patient care through more accurate diagnostics, improved risk stratification, and better tumor monitoring.   Pervious fellows have pursued successful careers in NIH funded-research basic science research, clinical academics, private practice, and industry.

Facilities

Training for the fellowship occurs in the state of the art facilities of Washington University School of Medicine/Barnes Jewish Hospital/St. Louis Children’s Hospital. The Molecular Genetic Pathology section is located in the 680,000 square-foot BJC Institute of Health (BJCIH) at Washington University School of Medicine which is an 11-story research building housing laboratories and support facilities and is Washington University’s largest building. Additional training is held in the state-of-the-art Cortex building on the edge of the medical campus known as the CORTEX District (Center of Research, Technology and Entrepreneurial Exchange).

Application

Applicants must be Board certified/Board eligible in Anatomic and/or Clinical Pathology, or Medical Genetics, and meet the requirements for medical licensure in Missouri.

Deadline for completed applications is November 1st.

The following information should be sent by email as pdf documents to Sue Pagano, Fellowship Coordinator at spagano@path.wustl.edu.

  1. Completed Fellowship Application
  2. Personal statement
  3. CV
  4. Copy of official USMLE transcripts
  5. Three recommendation letters directly emailed by your references or program coordinator

Faculty and trainees

Faculty

All
by Last Name
Filtered by

Current trainees

All
by Last Name
Filtered by

Past trainees

All
by Last Name
Filtered by

Yumei Chen, MD, PhD
Mohammad Hussaini, MD
Jochen Lennerz, MD, PhD
Amir Mohammadi, MD
Cecilia Yeung, MD


For further information please contact Sue Pagano.
Phone: (314) 747-0687
spagano@path.wustl.edu